Insulin signaling in the transcriptional and posttranscriptional regulation of CYP2E1 expression. - Wikidata - awgldk - TriplyDB

Insulin signaling in the transcriptional and posttranscriptional regulation of CYP2E1 expression.

Insulin signaling in the transcriptional and posttranscriptional regulation of CYP2E1 expression.

http://www.wikidata.org/entity/Q43875818

about

Diallyl Sulfide: Potential Use in Novel Therapeutic Interventions in Alcohol, Drugs, and Disease Mediated Cellular Toxicity by Targeting Cytochrome P450 2E1 Mechanisms of mitochondrial targeting of cytochrome P450 2E1: physiopathological role in liver injury and obesity Dopamine D2-Receptor Antagonists Down-Regulate CYP1A1/2 and CYP1B1 in the Rat Liver Predominant role of peripheral catecholamines in the stress-induced modulation of CYP1A2 inducibility by benzo(alpha)pyrene Global phosphoproteomics identifies a major role for AKT and 14-3-3 in regulating EDC3 Increased cytochrome P4502E1 expression and altered hydroxyeicosatetraenoic acid formation mediate diabetic vascular dysfunction: rescue by guanylyl-cyclase activation.The worker honeybee fat body proteome is extensively remodeled preceding a major life-history transition.Decreased exposure of simvastatin and simvastatin acid in a rat model of type 2 diabetes.Chronic ethanol feeding potentiates Fas Jo2-induced hepatotoxicity: role of CYP2E1 and TNF-alpha and activation of JNK and P38 MAP kinase.Regulation of the effects of CYP2E1-induced oxidative stress by JNK signaling.Pathogenesis of alcoholic liver disease: role of oxidative metabolism.Non-alcoholic steatohepatitis: definitions and pathogenesis.Role of CYP2E1 in ethanol-induced oxidant stress, fatty liver and hepatotoxicity.The role of intracellular signaling in insulin-mediated regulation of drug metabolizing enzyme gene and protein expression.Diabetes mellitus increases the in vivo activity of cytochrome P450 2E1 in humans.Organotypic liver culture models: meeting current challenges in toxicity testing.Alcohol steatosis and cytotoxicity: the role of cytochrome P4502E1 and autophagy Review article: role of oxidative stress in the progression of non-alcoholic steatosis.CYP2E1 and oxidative liver injury by alcohol.CYP2E1-dependent oxidative stress and toxicity: role in ethanol-induced liver injury.Sex steroid hormones regulate constitutive expression of Cyp2e1 in female mouse liver.Mechanisms and outcomes of drug- and toxicant-induced liver toxicity in diabetes.Molecular mechanisms of alcoholic fatty liver Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and JNK MAPK.High fat diet induced obesity alters ovarian phosphatidylinositol-3 kinase signaling gene expression.Nrf2 and antioxidant defense against CYP2E1 toxicity.Human placental lactogen induces CYP2E1 expression via PI 3-kinase pathway in female human hepatocytes.Cytochrome P450 2E1 and hyperglycemia-induced liver injury.Toxicological implications of modulation of gene expression by microRNAs.Drug disposition in pathophysiological conditions.Identification of a 16-nucleotide sequence that mediates post-transcriptional regulation of rat CYP2E1 by insulin.S-allylcysteine Improves Streptozotocin-Induced Alterations of Blood Glucose, Liver Cytochrome P450 2E1, Plasma Antioxidant System, and Adipocytes Hormones in Diabetic Rats Histone modification-mediated CYP2E1 gene expression and apoptosis of HepG2 cells.Gene copy number variation analysis reveals dosage-insensitive expression of CYP2E1.Regulatory sequence responsible for insulin destabilization of cytochrome P450 2B1 (CYP2B1) mRNA.Metabolic liver disease of obesity and role of adipose tissue in the pathogenesis of nonalcoholic fatty liver disease.Cytochrome P450 2E1 contributes to ethanol-induced fatty liver in mice.Reduced susceptibility of muscle-specific insulin receptor knockout mice to colon carcinogenesis.Hepatotoxicity associated with acarbose therapy.Progressive obesity alters ovarian insulin, phosphatidylinositol-3 kinase, and chemical metabolism signaling pathways and potentiates ovotoxicity induced by phosphoramide mustard in mice.

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P2860

Insulin signaling in the transcriptional and posttranscriptional regulation of CYP2E1 expression.

http://www.wikidata.org/entity/Q43875818

description

2002 nî lūn-bûn

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2002年の論文

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年學術文章

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2002年學術文章

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name

Insulin signaling in the trans ...... gulation of CYP2E1 expression.

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type

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Insulin signaling in the trans ...... gulation of CYP2E1 expression.

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Insulin signaling in the trans ...... gulation of CYP2E1 expression.

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Kimberley J Woodcroft

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Mikehl S Hafner

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Raymond F Novak

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P2860

Identification of a sequence in the PEPCK gene that mediates a negative effect of insulin on transcription

Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability

Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling

Excess risk of primary liver cancer in patients with diabetes mellitus.

Risk assessment: toxicity from chemical exposure resulting from enhanced expression of CYP2E1.

Assessment of the roles of mitogen-activated protein kinase, phosphatidylinositol 3-kinase, protein kinase B, and protein kinase C in insulin inhibition of cAMP-induced phosphoenolpyruvate carboxykinase gene transcription.

The induction of a specific form of cytochrome P-450 (P-450j) by fasting.

The hsp90-based chaperone system: involvement in signal transduction from a variety of hormone and growth factor receptors.

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

Effects of fatty acids and ketone bodies on cytochromes P450 2B, 4A, and 2E1 expression in primary cultured rat hepatocytes.

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