about
Lipid rafts are primary mediators of amyloid oxidative attack on plasma membrane.Nucleophosmin contains amyloidogenic regions that are able to form toxic aggregates under physiological conditions.Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomers.Oleuropein aglycone induces autophagy via the AMPK/mTOR signalling pathway: a mechanistic insight.TDP-43 inclusion bodies formed in bacteria are structurally amorphous, non-amyloid and inherently toxic to neuroblastoma cells.Effect of molecular chaperones on aberrant protein oligomers in vitro: super-versus sub-stoichiometric chaperone concentrations.Single molecule experiments emphasize GM1 as a key player of the different cytotoxicity of structurally distinct Aβ1-42 oligomers.Plasma membrane injury depends on bilayer lipid composition in Alzheimer's disease.S-linolenoyl glutathione intake extends life-span and stress resistance via Sir-2.1 upregulation in Caenorhabditis elegans.Novel S-acyl glutathione derivatives prevent amyloid oxidative stress and cholinergic dysfunction in Alzheimer disease models.Lipid rafts mediate amyloid-induced calcium dyshomeostasis and oxidative stress in Alzheimer's disease.Neuronal differentiation of human mesenchymal stromal cells increases their resistance to Aβ42 aggregate toxicity.Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers.Toxicity of protein oligomers is rationalized by a function combining size and surface hydrophobicity.Transthyretin suppresses the toxicity of oligomers formed by misfolded proteins in vitro.Extracellular chaperones prevent Aβ42-induced toxicity in rat brains.Allele specific Taqman-based real-time PCR assay to quantify circulating BRAFV600E mutated DNA in plasma of melanoma patientsOxidative Stress in Neurodegenerative Diseases: From a Mitochondrial Point of View.Proteostasis Failure in Neurodegenerative Diseases: Focus on Oxidative StressPartial Failure of Proteostasis Systems Counteracting TDP-43 Aggregates in Neurodegenerative DiseasesOxidative Stress and Mitochondrial Damage in Neurodegenerative Diseases: From Molecular Mechanisms to Targeted Therapies
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Q33539215-2DE62DDF-2719-4198-BF9D-AA344EBC63D0Q34044015-5B622C9C-8913-4078-9A81-320FAA34C202Q36140162-DC560EA8-7778-4F13-8559-05E816F71215Q36546347-19C83CC0-CDDB-4FBA-A172-FE1DF01D9C6EQ37534690-7C7AD6B9-1EFC-415D-B096-6A0B955AABC4Q38799326-1ADDE28E-421F-4862-BCC7-1255959CF5BEQ38812631-D6EB8F7C-73F6-4BDC-9376-3175A2633ABDQ39016766-1ED0E03F-037E-4EEC-B7D5-1B23455A123DQ39191008-36FED00B-F330-4DFC-8631-3527C87AAF34Q39397930-100BADD9-9056-461E-8916-BAD27E2E3EBBQ43916351-09D8CA8B-5DAC-4953-A5B7-6000B5485DBDQ44397990-E54D64B0-E2B9-4176-94F4-B6EE72761541Q46241023-267D3223-3F55-4B62-B29C-FA71EBBC77FCQ46858479-9044DC7F-9858-42DF-82E3-C007E42B7936Q46989286-84095462-78AD-4028-BCB8-D46C3FA449C2Q50747899-24665C7E-8FA3-41AB-9551-A824119668F4Q57975214-169279EC-F485-4EA6-B00E-048744EF972AQ64982512-B1D90475-3A2E-4DD9-AA97-FCDC341CC436Q92063917-FA9BE8E7-8DAA-4883-B8F3-EC458A80B66EQ92258049-AB338366-DE69-4B44-AA86-D9E7DA7D2999Q95856487-BFBB97BC-EA02-4947-A60A-16064234EABB
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description
hulumtuese
@sq
researcher
@en
ricercatrice
@it
wetenschapper
@nl
հետազոտող
@hy
name
Roberta Cascella
@ast
Roberta Cascella
@en
Roberta Cascella
@es
Roberta Cascella
@nl
Roberta Cascella
@sl
type
label
Roberta Cascella
@ast
Roberta Cascella
@en
Roberta Cascella
@es
Roberta Cascella
@nl
Roberta Cascella
@sl
prefLabel
Roberta Cascella
@ast
Roberta Cascella
@en
Roberta Cascella
@es
Roberta Cascella
@nl
Roberta Cascella
@sl
P214
P1053
K-5122-2016
P106
P1153
35726651400
P21
P214
P31
P3829
P396
IT\ICCU\CFIV\281056
P496
0000-0001-9856-6843
P569
1983-01-01T00:00:00Z
P735
P7859
viaf-307346879