Substrate specificity for rat cytochrome P450 (CYP) isoforms: screening with cDNA-expressed systems of the rat.
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Drug-Induced Liver Toxicity and Prevention by Herbal Antioxidants: An OverviewPharmGKB summary: very important pharmacogene information for cytochrome P-450, family 2, subfamily A, polypeptide 6Virtual Experiments Enable Exploring and Challenging Explanatory Mechanisms of Immune-Mediated P450 Down-RegulationDevelopment of an optimized procedure for the preparation of rat intestinal microsomes: comparison of hepatic and intestinal microsomal cytochrome P450 enzyme activities in two rat strainsChanges in maternal liver Cyp2c and Cyp2d expression and activity during rat pregnancyComputational Identification of the Paralogs and Orthologs of Human Cytochrome P450 Superfamily and the Implication in Drug DiscoveryIsoform-specific regulation of cytochrome P450 expression and activity by estradiol in female rats.Cytochromes P450 and experimental models of drug metabolism.Interactions of herbs with cytochrome P450.Induction of cytochromes P450 1A1 and 1A2 suppresses formation of DNA adducts by carcinogenic aristolochic acid I in rats in vivoInhibitory Effects of Baicalin on the Expression and Activity of CYP3A Induce the Pharmacokinetic Changes of Midazolam in RatsInfluence of dietary fat type on benzo(a)pyrene [B(a)P] biotransformation in a B(a)P-induced mouse model of colon cancer.Treprostinil Improves Hepatic Cytochrome P450 Activity during Rat Liver Transplantation.Pharmacokinetic changes of drugs in a rat model of liver cirrhosis induced by dimethylnitrosamine, alone and in combination with diabetes mellitus induced by streptozotocin.The effect of fenofibric acid on the pharmacokinetics and pharmacodynamics of warfarin in rats.HepG2 cells as an in vitro model for evaluation of cytochrome P450 induction by xenobiotics.Trans-chromosomic mice containing a human CYP3A cluster for prediction of xenobiotic metabolism in humans.Does CYP2E1 play a major role in the aggravation of isoniazid toxicity by rifampicin in human hepatocytes?Increased exposure of vitamin A by Chrysanthemum morifolium Ramat extract in rat was not via induction of CYP1A1, CYP1A2, and CYP2B1.Long-term stability of primary rat hepatocytes in micropatterned cocultures.Age-related changes in hepatic activity and expression of detoxification enzymes in male rats.Effect of triacontanol on the pharmacokinetics of docetaxel in rats associated with induction of cytochrome P450 3A1/2.Study of the upregulation of the activity of cytochrome P450 3A isoforms by Astragalus injection and Astragalus granules in rats and in cells.Plasma pharmacokinetics of midazolam in chickens, turkeys, pheasants and bobwhite quail.The herbicide metolachlor induces liver cytochrome P450s 2B1/2 and 3A1/2, but not thyroxine-uridine dinucleotide phosphate glucuronosyltransferase and associated thyroid gland activity.Demethylation of radiolabelled dextromethorphan in rat microsomes and intact hepatocytes.Phenacetin and chlorzoxazone biotransformation in aging male Fischer 344 rats.Cryopreserved rat, dog and monkey hepatocytes: measurement of drug metabolizing enzymes in suspensions and cultures.Role of CYP3A enzymes in the biotransformation of triazolam in rat liver.Cytochrome P450-dependent metabolism of midazolam in hepatic microsomes from chickens, turkeys, pheasant and bobwhite quail.Effect of ursodeoxycholic acid on the pharmacokinetics of midazolam and CYP3A in the liver and intestine of rats.Age-specific pulmonary cytochrome P-450 3A1 expression in postnatal and adult rats.Hepatic and intestinal CYP3A expression and activity in broilers.An inhibition study of beauvericin on human and rat cytochrome P450 enzymes and its pharmacokinetics in rats.Species-related exposure of phase II metabolite gemfibrozil 1-O-β-glucuronide between human and mice: A net induction of mouse P450 activity was revealed.Effect of methamphetamine on cytochrome P450 activity.Pregnane X receptor and constitutive androstane receptor modulate differently CYP3A-mediated metabolism in early- and late-stage cholestasis.siRNA-mediated knockdown of P450 oxidoreductase in rats: a tool to reduce metabolism by CYPs and increase exposure of high clearance compounds.Comparative study on altered hepatic metabolism of CYP3A substrates in rats with glycerol-induced acute renal failure.Effects of Phyllanthus amarus on the pharmacokinetics of midazolam and cytochrome P450 activities in rats.
P2860
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P2860
Substrate specificity for rat cytochrome P450 (CYP) isoforms: screening with cDNA-expressed systems of the rat.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Substrate specificity for rat ...... -expressed systems of the rat.
@en
Substrate specificity for rat cytochrome P450
@nl
type
label
Substrate specificity for rat ...... -expressed systems of the rat.
@en
Substrate specificity for rat cytochrome P450
@nl
prefLabel
Substrate specificity for rat ...... -expressed systems of the rat.
@en
Substrate specificity for rat cytochrome P450
@nl
P2093
P1476
Substrate specificity for rat ...... -expressed systems of the rat.
@en
P2093
Kaoru Kobayashi
Kikuko Urashima
Noriaki Shimada
P304
P356
10.1016/S0006-2952(01)00843-7
P407
P577
2002-03-01T00:00:00Z