450K-array analysis of chronic lymphocytic leukemia cells reveals global DNA methylation to be relatively stable over time and similar in resting and proliferative compartments.
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Genomic and epigenomic heterogeneity in chronic lymphocytic leukemiaGenome-wide DNA methylation profiling integrated with gene expression profiling identifies PAX9 as a novel prognostic marker in chronic lymphocytic leukemiaDifferential Analysis of Genetic, Epigenetic, and Cytogenetic Abnormalities in AMLValidation of ZAP-70 methylation and its relative significance in predicting outcome in chronic lymphocytic leukemia.Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemiaDifferential methylation in CN-AML preferentially targets non-CGI regions and is dictated by DNMT3A mutational status and associated with predominant hypomethylation of HOX genes.Characteristic DNA methylation profiles in peripheral blood monocytes are associated with inflammatory phenotypes of asthma.Locally disordered methylation forms the basis of intratumor methylome variation in chronic lymphocytic leukemia.Genetic and epigenetic profiling of CLL disease progression reveals limited somatic evolution and suggests a relationship to memory-cell developmentmiR-155 targets histone deacetylase 4 (HDAC4) and impairs transcriptional activity of B-cell lymphoma 6 (BCL6) in the Eμ-miR-155 transgenic mouse modelDistinct transcriptional control in major immunogenetic subsets of chronic lymphocytic leukemia exhibiting subset-biased global DNA methylation profiles.Inter- and intra-patient clonal and subclonal heterogeneity of chronic lymphocytic leukaemia: evidences from circulating and lymph nodal compartments.Metabolism pathways in chronic lymphocytic leukemia.Intratumoral Heterogeneity of the Epigenome.Epigenetic silencing of miR-26A1 in chronic lymphocytic leukemia and mantle cell lymphoma: Impact on EZH2 expressionChronic lymphocytic leukemia: molecular heterogeneity revealed by high-throughput genomicsPrognostic impact of epigenetic classification in chronic lymphocytic leukemia: The case of subset #2.DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemiaANGPT2 promoter methylation is strongly associated with gene expression and prognosis in chronic lymphocytic leukemia.Global DNA methylation profiling reveals new insights into epigenetically deregulated protein coding and long noncoding RNAs in CLL.Pro-apoptotic TP53 homolog TAp63 is repressed via epigenetic silencing and B-cell receptor signalling in chronic lymphocytic leukaemia.Uncovering the DNA methylome in chronic lymphocytic leukemia.Do age-related changes in DNA methylation play a role in the development of age-related diseases?Evolving understanding of the CLL genome.Epigenetic roots of immunologic disease and new methods for examining chromatin regulatory pathways.Molecular pathogenesis of CLL and its evolution.The molecular pathogenesis of chronic lymphocytic leukaemia.RPPA-based protein profiling reveals eIF4G overexpression and 4E-BP1 serine 65 phosphorylation as molecular events that correspond with a pro-survival phenotype in chronic lymphocytic leukemia.Genome-wide methylation analyses identify a subset of mantle cell lymphoma with a high number of methylated CpGs and aggressive clinicopathological features.IL-10 production by CLL cells is enhanced in the anergic IGHV mutated subset and associates with reduced DNA methylation of the IL10 locus.CD18 (ITGB2) expression in chronic lymphocytic leukaemia is regulated by DNA methylation-dependent and -independent mechanismsGlobal measures of peripheral blood-derived DNA methylation as a risk factor in the development of mature B-cell neoplasms.MCPH1 maintains long-term epigenetic silencing of ANGPT2 in chronic lymphocytic leukemia.DNA methylation profiles of long- and short-term glioblastoma survivorsGenome-wide DNA methylation assay reveals novel candidate biomarker genes in cervical cancer.Alterations in DNA methylation/demethylation intermediates predict clinical outcome in chronic lymphocytic leukemiaChromatin marks shape mutation landscape at early stage of cancer progression.Combining cytogenetic and epigenetic approaches in chronic lymphocytic leukemia improves prognosis prediction for patients with isolated 13q deletion.Gene-body hypermethylation controlled cryptic promoter and miR26A1-dependent EZH2 regulation of TET1 gene activity in chronic lymphocytic leukemia.Promoter methylation patterns in Richter syndrome affect stem-cell maintenance and cell cycle regulation and differ from de novo diffuse large B-cell lymphoma.
P2860
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P2860
450K-array analysis of chronic lymphocytic leukemia cells reveals global DNA methylation to be relatively stable over time and similar in resting and proliferative compartments.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
450K-array analysis of chronic ...... nd proliferative compartments.
@en
450K-array analysis of chronic ...... nd proliferative compartments.
@nl
type
label
450K-array analysis of chronic ...... nd proliferative compartments.
@en
450K-array analysis of chronic ...... nd proliferative compartments.
@nl
prefLabel
450K-array analysis of chronic ...... nd proliferative compartments.
@en
450K-array analysis of chronic ...... nd proliferative compartments.
@nl
P2093
P2860
P921
P356
P1433
P1476
450K-array analysis of chronic ...... nd proliferative compartments.
@en
P2093
C Sundström
G Juliusson
H Göransson-Kultima
K E Smedby
L Mansouri
P2860
P2888
P304
P356
10.1038/LEU.2012.245
P577
2012-08-27T00:00:00Z
P5875
P6179
1049183927