Hypothiocyanous acid reactivity with low-molecular-mass and protein thiols: absolute rate constants and assessment of biological relevance.
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Protein oxidation and peroxidationKinetics and mechanisms of thiol-disulfide exchange covering direct substitution and thiol oxidation-mediated pathwaysThe cysteine proteomeHypothiocyanous acid oxidation of tubulin cysteines inhibits microtubule polymerization.Small molecular, macromolecular, and cellular chloramines react with thiocyanate to give the human defense factor hypothiocyanite.The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophagesMyeloperoxidase-derived oxidation: mechanisms of biological damage and its preventionSelenium-containing amino acids are targets for myeloperoxidase-derived hypothiocyanous acid: determination of absolute rate constants and implications for biological damageThiocyanate supplementation decreases atherosclerotic plaque in mice expressing human myeloperoxidase.Antiinflammatory and Antimicrobial Effects of Thiocyanate in a Cystic Fibrosis Mouse Model.Inactivation of thiol-dependent enzymes by hypothiocyanous acid: role of sulfenyl thiocyanate and sulfenic acid intermediates.Linking Inflammation and Parkinson Disease: Hypochlorous Acid Generates Parkinsonian PoisonsMyeloperoxidase-derived oxidants inhibit sarco/endoplasmic reticulum Ca2+-ATPase activity and perturb Ca2+ homeostasis in human coronary artery endothelial cells.Biochemical mechanisms and therapeutic potential of pseudohalide thiocyanate in human health.Reactivity of disulfide bonds is markedly affected by structure and environment: implications for protein modification and stability.The role of hypothiocyanous acid (HOSCN) in biological systems.Reactions and reactivity of myeloperoxidase-derived oxidants: differential biological effects of hypochlorous and hypothiocyanous acids.Selenium-containing amino acids as direct and indirect antioxidants.Conditional pharmacology/toxicology V: ambivalent effects of thiocyanate upon the development and the inhibition of experimental arthritis in rats by aurothiomalate (Myocrysin®) and metallic silver.Posttranslational protein modifications by reactive nitrogen and chlorine species and strategies for their prevention and elimination.Detection of the halogenating activity of heme peroxidases in leukocytes by aminophenyl fluorescein.Reaction of low-molecular-mass organoselenium compounds (and their sulphur analogues) with inflammation-associated oxidants.One- and two-electron oxidation of thiols: mechanisms, kinetics and biological fates.Lactoperoxidase as a potential drug target.Role of Hypohalous Acids in Basement Membrane Homeostasis.Exposure of aconitase to smoking-related oxidants results in iron loss and increased iron response protein-1 activity: potential mechanisms for iron accumulation in human arterial cells.Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes.Secreted heme peroxidase from Dictyostelium discoideum: Insights into catalysis, structure, and biological role.Pseudomonas aeruginosa defense systems against microbicidal oxidants.Reactivity toward oxygen radicals and antioxidant action of thiol compounds.Biological Activities and Potential Oral Applications of N-Acetylcysteine: Progress and Prospects.
P2860
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P2860
Hypothiocyanous acid reactivity with low-molecular-mass and protein thiols: absolute rate constants and assessment of biological relevance.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
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2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
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2009年學術文章
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name
Hypothiocyanous acid reactivit ...... sment of biological relevance.
@en
Hypothiocyanous acid reactivit ...... sment of biological relevance.
@nl
type
label
Hypothiocyanous acid reactivit ...... sment of biological relevance.
@en
Hypothiocyanous acid reactivit ...... sment of biological relevance.
@nl
prefLabel
Hypothiocyanous acid reactivit ...... sment of biological relevance.
@en
Hypothiocyanous acid reactivit ...... sment of biological relevance.
@nl
P2860
P356
P1433
P1476
Hypothiocyanous acid reactivit ...... sment of biological relevance.
@en
P2093
David I Pattison
Ojia Skaff
P2860
P304
P356
10.1042/BJ20090276
P407
P577
2009-07-29T00:00:00Z