Impact of CYP2C9 amino acid polymorphisms on glyburide kinetics and on the insulin and glucose response in healthy volunteers.
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Applications of CYP450 testing in the clinical settingEffects of St John's wort and CYP2C9 genotype on the pharmacokinetics and pharmacodynamics of gliclazideIdentification of the human cytochromes P450 catalysing the rate-limiting pathways of gliclazide eliminationPharmacogenetics in type 2 diabetes: influence on response to oral hypoglycemic agentsDosing Recommendations for Concomitant Medications During 3D Anti-HCV TherapyPharmacogenomics and drug response in cardiovascular disordersPersonalized medicine in Type 2 DiabetesA Common Susceptibility Gene for Type 2 Diabetes Is Associated with Drug Response to a DPP-4 Inhibitor: Pharmacogenomic Cohort in Okinawa JapanGlibenclamide induces collagen IV catabolism in high glucose-stimulated mesangial cells.Pharmacogenomics of Drug Response in Type 2 Diabetes: Toward the Definition of Tailored Therapies?Individualized therapy for type 2 diabetes: clinical implications of pharmacogenetic data.Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment.Investigating the Role of Plasma Glucose Concentration as a Phenotypic Marker for CYP2C9 Genetic Variants, in the Diabetic Population of GujaratLoss-of-function CYP2C9 variants: finding the correct clinical role for Type 2 diabetes pharmacogenetic testingSulfonylurea pharmacogenomics in Type 2 diabetes: the influence of drug target and diabetes risk polymorphisms.CYP2C9 genotype and pharmacodynamic responses to losartan in patients with primary and secondary kidney diseases.Pharmacogenomics of oral antidiabetic medications: current data and pharmacoepigenomic perspective.Pharmacogenetics of Anti-Diabetes Drugs.Implications of pharmacogenetics for individualizing drug treatment and for study design.Contributions of human cytochrome P450 enzymes to glyburide metabolism.Expansion of a PBPK model to predict disposition in pregnant women of drugs cleared via multiple CYP enzymes, including CYP2B6, CYP2C9 and CYP2C19Regulation of mammalian physiology, development, and disease by the sphingosine 1-phosphate and lysophosphatidic acid receptors.Clinical relevance of genetic polymorphisms in the human CYP2C9 gene.Effect of rifampicin on the pharmacokinetics and pharmacodynamics of nateglinide in healthy subjects.Pharmacogenetics in type 2 diabetes: potential implications for clinical practiceImpact of inter-individual differences in drug metabolism and pharmacokinetics on safety evaluation.Effects of clarithromycin and grapefruit juice on the pharmacokinetics of glibenclamide.Elucidating rifampin's inducing and inhibiting effects on glyburide pharmacokinetics and blood glucose in healthy volunteers: unmasking the differential effects of enzyme induction and transporter inhibition for a drug and its primary metabolite.Sitagliptin, an dipeptidyl peptidase-4 inhibitor, does not alter the pharmacokinetics of the sulphonylurea, glyburide, in healthy subjectsPharmacogenetics of glucose-lowering drug treatment: a systematic review.A note on population analysis of dissolution-absorption models using the inverse Gaussian function.Are we optimizing gestational diabetes treatment with glyburide? The pharmacologic basis for better clinical practiceCYP2C93 variant is associated with antidiabetes efficacy of gliclazide in Chinese type 2 diabetes patientsPharmacogenetics of oral antidiabetic drugs.Pharmacogenetics and personalized treatment of type 2 diabetesCytochrome P450 2C9-CYP2C9.Identification of the major human hepatic and placental enzymes responsible for the biotransformation of glyburide.Genetic polymorphisms in diabetes: influence on therapy with oral antidiabetics.Clinical pharmacokinetics and pharmacodynamics of vildagliptin.CYP2C metabolism of oral antidiabetic drugs--impact on pharmacokinetics, drug interactions and pharmacogenetic aspects.
P2860
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P2860
Impact of CYP2C9 amino acid polymorphisms on glyburide kinetics and on the insulin and glucose response in healthy volunteers.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Impact of CYP2C9 amino acid po ...... esponse in healthy volunteers.
@en
Impact of CYP2C9 amino acid po ...... esponse in healthy volunteers.
@nl
type
label
Impact of CYP2C9 amino acid po ...... esponse in healthy volunteers.
@en
Impact of CYP2C9 amino acid po ...... esponse in healthy volunteers.
@nl
prefLabel
Impact of CYP2C9 amino acid po ...... esponse in healthy volunteers.
@en
Impact of CYP2C9 amino acid po ...... esponse in healthy volunteers.
@nl
P2093
P356
P1476
Impact of CYP2C9 amino acid po ...... esponse in healthy volunteers.
@en
P2093
Christian Meisel
Ingolf Meineke
Ivar Roots
Julia Kirchheiner
Jürgen Brockmöller
Steffen Bauer
Wolfgang Rohde
P304
P356
10.1067/MCP.2002.122476
P407
P577
2002-04-01T00:00:00Z