Increased neocortical expression of the P2X7 receptor after status epilepticus and anticonvulsant effect of P2X7 receptor antagonist A-438079.
about
P2X receptors as targets for the treatment of status epilepticusRole of P2X7 and P2Y2 receptors on α-secretase-dependent APP processing: Control of amyloid plaques formation "in vivo" by P2X7 receptorAltered morphological dynamics of activated microglia after induction of status epilepticus.Critical Evaluation of P2X7 Receptor Antagonists in Selected Seizure ModelsActivation of P2X7 receptor and NLRP3 inflammasome assembly in hippocampal glial cells mediates chronic stress-induced depressive-like behaviorsRNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis.Purinergic system dysfunction in mood disorders: a key target for developing improved therapeutics.ATP as a multi-target danger signal in the brain.microRNA targeting of the P2X7 purinoceptor opposes a contralateral epileptogenic focus in the hippocampus.Adenosine A2A receptor and ecto-5'-nucleotidase/CD73 are upregulated in hippocampal astrocytes of human patients with mesial temporal lobe epilepsy (MTLE).P2X and P2Y receptors—role in the pathophysiology of the nervous system.Seizures Due to a KCNQ2 Mutation: Treatment with Vitamin B6.Inhibition of P2X7 receptors improves outcomes after traumatic brain injury in rats.Neuroinflammatory targets and treatments for epilepsy validated in experimental models.Silencing of P2X7R by RNA interference in the hippocampus can attenuate morphological and behavioral impact of pilocarpine-induced epilepsy.Microglia-Neuron Communication in Epilepsy.The microglial ATP-gated ion channel P2X7 as a CNS drug target.The ATP-Gated P2X7 Receptor As a Target for the Treatment of Drug-Resistant EpilepsyInvolvement of P2X7 receptor in neuronal degeneration triggered by traumatic injury.Macrophage-Inducible C-Type Lectin/Spleen Tyrosine Kinase Signaling Pathway Contributes to Neuroinflammation After Subarachnoid Hemorrhage in Rats.Evaluation of the Anticonvulsant Effect of Brilliant Blue G, a Selective P2X7 Receptor Antagonist, in the iv PTZ-, Maximal Electroshock-, and 6 Hz-Induced Seizure Tests in MiceAntagomirs targeting microRNA-134 increase hippocampal pyramidal neuron spine volume in vivo and protect against pilocarpine-induced status epilepticus.Extracellular ATP Activates the NLRP3 Inflammasome and Is an Early Danger Signal of Skin Allograft Rejection.Inhibition of P2X7 Receptor Ameliorates Nuclear Factor-Kappa B Mediated Neuroinflammation Induced by Status Epilepticus in Rat Hippocampus.Novel Therapeutic Targets Against Spreading Depression.LKB1/AMPK-Mediated Regulation by Gentiopicroside Ameliorates P2x7R-Dependent Alcoholic Hepatosteatosis.Up-regulation of P2X7 receptor-mediated inhibition of GABA uptake by nerve terminals of the human epileptic neocortex.Pilocarpine-Induced Status Epilepticus Increases the Sensitivity of P2X7 and P2Y1 Receptors to Nucleotides at Neural Progenitor Cells of the Juvenile Rodent Hippocampus.Increased Expression and Cellular Localization of P2X7R in Cortical Lesions of Patients With Focal Cortical Dysplasia.Microglia after Seizures and in Epilepsy.Persistent Protection Against Pathology and Paroxysms by P2X7R Antagonism.Complex spectrum of phenobarbital effects in a mouse model of neonatal hypoxia-induced seizuresRe-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody
P2860
Q26823175-037C493B-E2EA-4E27-95F2-FA093A627E74Q26824248-EB9887CD-5984-4A12-ACC1-11C7D99994EAQ27303510-D2A26820-E465-4F7C-8361-177C5B27A183Q27342573-3332E2E2-C2C6-4807-8466-7A091D12BDAEQ29994732-1AB68BA2-D38C-47EE-ADB0-A699ACB55FB5Q30836611-238CADC6-ADB1-4686-8463-83F5E05F9DA0Q34674792-D0581D86-895C-471E-AC5B-88107DF5DBA2Q35545478-641D46BE-DF04-4684-BD68-723940D7AEEEQ36343295-03FF176A-03B2-40D1-A26C-50210B3D58CBQ37442082-E7BAE28C-9D98-4CCC-9894-21B0DAB9F1E7Q38296527-8FD550C5-BF72-456E-86E6-F4F5D87ACC1BQ38601707-1594CD03-BE97-410F-B538-7C46F1CF988BQ38617347-AADE9833-32F9-49F2-B3C8-4FD73795FE32Q38662997-06217FA7-B264-488C-85B9-C3A607F89609Q38679789-3C7A3EC5-A19C-4E69-B594-3C7C0DB9ACA8Q38836935-0FD06733-A7A8-4FCB-8E64-652D0A734DD2Q38843107-5505032D-5F13-4738-A885-8F4B6C69FA1EQ38956264-C9F1354C-8654-4BEC-AE1D-EDDDAAB3B6F7Q41969599-A8962C8F-2D77-46AA-92CD-64BFCA899C02Q42020457-2F515096-7E77-446D-8A51-39E4DF17ECD9Q42727469-4EE82E7F-C840-413B-948A-C26A32E1D345Q44393750-56E4CE1D-8316-4EE4-8AB9-CF89A759BAD1Q47112090-A0ED1FFF-654D-4F61-8DCE-FA4935FF473DQ47736252-BE039DE5-80B5-4DFB-AECE-D1C9B776ED61Q47787596-6364F611-7AFE-4FE1-9F40-D525571D6781Q48234896-B98E5D78-7D21-45DF-9A38-9DA6D8D08715Q48272726-EBF373AE-CAA8-4EEE-8D26-CBC827690D9BQ48657250-CF29C1F5-7707-4D27-A3D3-489487ED2FA9Q49143369-37CF97F4-689B-4ACD-9786-9AFCF3CEAA51Q52337757-D04A8C7C-0FD1-4132-A5D5-4DD4ACC415EAQ54989642-839B6491-4A83-462F-B90B-631AA63804C6Q57793911-08D6E7DB-EB3F-46CB-A527-74938CA42817Q58451239-D0025B9B-8F91-4492-B1F7-3D08C778B9B0
P2860
Increased neocortical expression of the P2X7 receptor after status epilepticus and anticonvulsant effect of P2X7 receptor antagonist A-438079.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh-hant
name
Increased neocortical expressi ...... receptor antagonist A-438079.
@en
Increased neocortical expressi ...... receptor antagonist A-438079.
@nl
type
label
Increased neocortical expressi ...... receptor antagonist A-438079.
@en
Increased neocortical expressi ...... receptor antagonist A-438079.
@nl
prefLabel
Increased neocortical expressi ...... receptor antagonist A-438079.
@en
Increased neocortical expressi ...... receptor antagonist A-438079.
@nl
P2093
P2860
P50
P356
P1433
P1476
Increased neocortical expressi ...... 7 receptor antagonist A-438079
@en
P2093
Alba Jimenez-Pacheco
Amaya Sanz-Rodriguez
Claire Mooney
Guillaume Mesuret
Katsuhiro Tanaka
P2860
P304
P356
10.1111/EPI.12257
P577
2013-06-28T00:00:00Z