Novel substrates and inhibitors of peptidylglycine alpha-amidating monooxygenase.
about
Amidation of Bioactive Peptides: The Structure of the Lyase Domain of the Amidating EnzymeCoordination of peroxide to the CuM center of peptidylglycine α-hydroxylating monooxygenase (PHM): structural and computational studyEvidence for substrate preorganization in the peptidylglycine α-amidating monooxygenase reaction describing the contribution of ground state structure to hydrogen tunnelingKinetic and stereochemical studies on novel inactivators of C-terminal amidationComparative effects of 4-phenyl-3-butenoic acid and vorinostat on cell growth and signalingUbiquitin and ubiquitin-derived peptides as substrates for peptidylglycine alpha-amidating monooxygenaseThiorphan, tiopronin, and related analogs as substrates and inhibitors of peptidylglycine alpha-amidating monooxygenase (PAM)Copper active sites in biologyImino-oxy acetic acid dealkylation as evidence for an inner-sphere alcohol intermediate in the reaction catalyzed by peptidylglycine alpha-hydroxylating monooxygenase.A bioactive peptide amidating enzyme is required for ciliogenesisInhibition of JNK and p38 MAPK phosphorylation by 5-(acetylamino)-4-oxo-6-phenyl-2-hexenoic acid methyl ester and 4-phenyl-butenoic acid decreases substance P-induced TNF-α upregulation in macrophagesSubstituted hippurates and hippurate analogs as substrates and inhibitors of peptidylglycine alpha-hydroxylating monooxygenase (PHM).p38 MAPK activation, JNK inhibition, neoplastic growth inhibition, and increased gap junction communication in human lung carcinoma and Ras-transformed cells by 4-phenyl-3-butenoic acid.Amidation inhibitors 4-phenyl-3-butenoic acid and 5-(acetylamino)-4-oxo-6-phenyl-2-hexenoic acid methyl ester are novel HDAC inhibitors with anti-tumorigenic properties.Inactivation of peptidylglycine α-hydroxylating monooxygenase by cinnamic acid analogs.Reaction mechanism of the bicopper enzyme peptidylglycine α-hydroxylating monooxygenaseKinetic and inhibition studies on substrate channelling in the bifunctional enzyme catalysing C-terminal amidationNN-dimethyl-1,4-phenylenediamine as an alternative reductant for peptidylglycine alpha-amidating mono-oxygenase catalysisStructure-activity relationships among inhibitors of peptidylglycine amidating monooxygenase.Role for an essential tyrosine in peptide amidation.Absence of an essential thiol in human glutaminyl cyclase: Implications for mechanism
P2860
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P2860
Novel substrates and inhibitors of peptidylglycine alpha-amidating monooxygenase.
description
1990 nî lūn-bûn
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1990年の論文
@ja
1990年学术文章
@wuu
1990年学术文章
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1990年学术文章
@zh-cn
1990年学术文章
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1990年学术文章
@zh-my
1990年学术文章
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1990年學術文章
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1990年學術文章
@zh-hant
name
Novel substrates and inhibitors of peptidylglycine alpha-amidating monooxygenase.
@en
Novel substrates and inhibitors of peptidylglycine alpha-amidating monooxygenase.
@nl
type
label
Novel substrates and inhibitors of peptidylglycine alpha-amidating monooxygenase.
@en
Novel substrates and inhibitors of peptidylglycine alpha-amidating monooxygenase.
@nl
prefLabel
Novel substrates and inhibitors of peptidylglycine alpha-amidating monooxygenase.
@en
Novel substrates and inhibitors of peptidylglycine alpha-amidating monooxygenase.
@nl
P356
P1433
P1476
Novel substrates and inhibitors of peptidylglycine alpha-amidating monooxygenase.
@en
P2093
P304
P356
10.1021/BI00471A006
P407
P577
1990-05-01T00:00:00Z