Potentially functional polymorphism in the promoter region of prodynorphin gene may be associated with protection against cocaine dependence or abuse.
about
Ancient and recent positive selection transformed opioid cis-regulation in humansA genetic polymorphism of the endogenous opioid dynorphin modulates monetary reward anticipation in the corticostriatal loopMicroarray studies of psychostimulant-induced changes in gene expression.Implications of genome wide association studies for addiction: are our a priori assumptions all wrong?Poststress block of kappa opioid receptors rescues long-term potentiation of inhibitory synapses and prevents reinstatement of cocaine seeking.Pharmacotherapy of addictions.Morphine enhances Tat-induced activation in murine microglia.When the DREAM is gone: from basic science to future prospectives in pain management and beyond.Alcohol dependence, disinhibited behavior and variation in the prodynorphin geneGenetics and drug use as a complex phenotype.Role of mu, delta and kappa opioid receptors in ethanol-reinforced operant responding in infant rats.Opioid neuropeptide genotypes in relation to heroin abuse: dopamine tone contributes to reversed mesolimbic proenkephalin expression.Perspectives on current directions in the neurobiology of addiction disorders relevant to genetic risk factors.Candidate genes for antidepressant response to selective serotonin reuptake inhibitorsDynorphin and the pathophysiology of drug addiction.The genetics of the opioid system and specific drug addictionsSearch for genetic markers and functional variants involved in the development of opiate and cocaine addiction and treatment.Opiate and cocaine addiction: from bench to clinic and back to the bench.Association of variants in MANEA with cocaine-related behaviors.A functional haplotype implicated in vulnerability to develop cocaine dependence is associated with reduced PDYN expression in human brain.The dynorphin/κ-opioid receptor system and its role in psychiatric disorders.Genomic variations and transcriptional regulation of the human mu-opioid receptor gene.Cell-specific effects of variants of the 68-base pair tandem repeat on prodynorphin gene promoter activity.Kappa opioid receptors regulate stress-induced cocaine seeking and synaptic plasticity.Association between VNTR Polymorphism in Promoter Region of Prodynorphin (PDYN) Gene and Methamphetamine Dependence.Corticotropin-releasing factor testing reveals a dose-dependent difference in methadone maintained vs control subjects.Prodynorphin gene promoter repeat associated with cocaine/alcohol codependence.Genetic association analyses of PDYN polymorphisms with heroin and cocaine addiction.
P2860
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P2860
Potentially functional polymorphism in the promoter region of prodynorphin gene may be associated with protection against cocaine dependence or abuse.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
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name
Potentially functional polymor ...... t cocaine dependence or abuse.
@en
Potentially functional polymor ...... t cocaine dependence or abuse.
@nl
type
label
Potentially functional polymor ...... t cocaine dependence or abuse.
@en
Potentially functional polymor ...... t cocaine dependence or abuse.
@nl
prefLabel
Potentially functional polymor ...... t cocaine dependence or abuse.
@en
Potentially functional polymor ...... t cocaine dependence or abuse.
@nl
P2093
P2860
P356
P1476
Potentially functional polymor ...... t cocaine dependence or abuse.
@en
P2093
Andrew C H Chen
K Steven LaForge
Kathy Bell
Pauline F McHugh
Rosemary P Schluger
Scott Kellogg
Suzanne M Leal
P2860
P304
P356
10.1002/AJMG.10362
P577
2002-05-01T00:00:00Z