Cytochrome P450 omega-hydroxylase pathway of tocopherol catabolism. Novel mechanism of regulation of vitamin E status. - Wikidata - awgldk - TriplyDB

Cytochrome P450 omega-hydroxylase pathway of tocopherol catabolism. Novel mechanism of regulation of vitamin E status.

Cytochrome P450 omega-hydroxylase pathway of tocopherol catabolism. Novel mechanism of regulation of vitamin E status.

http://www.wikidata.org/entity/Q43984576

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Common variants of cytochrome P450 4F2 exhibit altered vitamin E-{omega}-hydroxylase specific activity CYP4F2 is a vitamin K1 oxidase: An explanation for altered warfarin dose in carriers of the V433M variant Cytochrome P450-dependent catabolism of vitamin K: ω-hydroxylation catalyzed by human CYP4F2 and CYP4F11 Vitamin E, antioxidant and nothing more Vitamin E function and requirements in relation to PUFA Intracellular transport of fat-soluble vitamins A and E Effect of Vitamin E on Glutathione-Dependent Enzymes Complexity of vitamin E metabolism Genetic Variations Involved in Vitamin E Status Synergistic Anticancer Effect of Tocotrienol Combined with Chemotherapeutic Agents or Dietary Components: A Review Insig-dependent ubiquitination and degradation of 3-hydroxy-3-methylglutaryl coenzyme a reductase stimulated by delta- and gamma-tocotrienols Influence of major structural features of tocopherols and tocotrienols on their omega-oxidation by tocopherol-omega-hydroxylase The Concise Guide to PHARMACOLOGY 2013/14: enzymes.Use of genetic data to guide therapy in arterial disease.Efficient dibutyltin (DBT) elimination by the microscopic fungus Metarhizium robertsii under conditions of intensive aeration and ascorbic acid supplementation.In vitro stable isotope labeling for discovery of novel metabolites by liquid chromatography-mass spectrometry: Confirmation of gamma-tocopherol metabolism in human A549 cell.PPAR/RXR Regulation of Fatty Acid Metabolism and Fatty Acid omega-Hydroxylase (CYP4) Isozymes: Implications for Prevention of Lipotoxicity in Fatty Liver Disease Analysis of multiple metabolites of tocopherols and tocotrienols in mice and humans.Cancer-preventive activities of tocopherols and tocotrienols.Vitamin E status and metabolism in adult and aged aryl hydrocarbon receptor null mice.The revised human liver cytochrome P450 "Pie": absolute protein quantification of CYP4F and CYP3A enzymes using targeted quantitative proteomics.Natural forms of vitamin E: metabolism, antioxidant, and anti-inflammatory activities and their role in disease prevention and therapy Fatty acid omega-oxidation as a rescue pathway for fatty acid oxidation disorders in humans.CYP4F2 rs2108622: a minor significant genetic factor of warfarin dose in Han Chinese patients with mechanical heart valve replacement Association of 1347 G/A cytochrome P450 4F2 (CYP4F2) gene variant with hypertension and stroke.Deuterium-labeled phylloquinone fed to α-tocopherol-injected rats demonstrates sensitivity of low phylloquinone-containing tissues to menaquinone-4 depletion Gamma-tocopherol--an underestimated vitamin?Serum α-tocopherol and γ-tocopherol concentrations and prostate cancer risk in the PLCO Screening Trial: a nested case-control study.Vitamin E transporters in cancer therapy.Increased vitamin E intake is associated with higher alpha-tocopherol concentration in the maternal circulation but higher alpha-carboxyethyl hydroxychroman concentration in the fetal circulation.Nutrigenomics of extra-virgin olive oil: A review.Nutraceutical functions of sesame: a review.Regulation of human cytochrome P450 4F2 expression by sterol regulatory element-binding protein and lovastatin.PharmGKB summary: very important pharmacogene information for CYP4F2 CYP4F2 genetic variant alters required warfarin dose δ-tocopherol is more active than α - or γ -tocopherol in inhibiting lung tumorigenesis in vivo Genetic polymorphism of cytochrome P450 4F2, vitamin E level and histological response in adults and children with nonalcoholic fatty liver disease who participated in PIVENS and TONIC clinical trials.Genome-wide association study identifies common variants associated with circulating vitamin E levels.α-Tocopherol injections in rats up-regulate hepatic ABC transporters, but not cytochrome P450 enzymes Why tocotrienols work better: insights into the in vitro anti-cancer mechanism of vitamin E.

P2860

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P2860

Cytochrome P450 omega-hydroxylase pathway of tocopherol catabolism. Novel mechanism of regulation of vitamin E status.

http://www.wikidata.org/entity/Q43984576

description

2002 nî lūn-bûn

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2002年の論文

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年學術文章

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2002年學術文章

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2002年學術文章

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name

Cytochrome P450 omega-hydroxyl ...... egulation of vitamin E status.

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Cytochrome P450 omega-hydroxyl ...... egulation of vitamin E status.

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type

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Cytochrome P450 omega-hydroxyl ...... egulation of vitamin E status.

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Cytochrome P450 omega-hydroxyl ...... egulation of vitamin E status.

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prefLabel

Cytochrome P450 omega-hydroxyl ...... egulation of vitamin E status.

@en

Cytochrome P450 omega-hydroxyl ...... egulation of vitamin E status.

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Journal of Biological Chemistry

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Cytochrome P450 omega-hydroxyl ...... egulation of vitamin E status.

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P2093

Robert S Parker

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Timothy J Sontag

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P2860

Role of human CYP4F2 in hepatic catabolism of the proinflammatory agent leukotriene B4

Formation of 20-hydroxyeicosatetraenoic acid, a vasoactive and natriuretic eicosanoid, in human kidney. Role of Cyp4F2 and Cyp4A11

Cloning and expression of a novel form of leukotriene B4 omega-hydroxylase from human liver

Identification of CYP4A11 as the major lauric acid omega-hydroxylase in human liver microsomes

Increased atherosclerosis in hyperlipidemic mice deficient in alpha -tocopherol transfer protein and vitamin E

Purification and characterization of recombinant rat hepatic CYP4F1

Molecular mechanisms of vitamin E transport.

Expression of the CYP4F3 gene. tissue-specific splicing and alternative promoters generate high and low K(m) forms of leukotriene B(4) omega-hydroxylase.

Inhibition and induction of human cytochrome P450 (CYP) enzymes.

gamma-tocopherol and its major metabolite, in contrast to alpha-tocopherol, inhibit cyclooxygenase activity in macrophages and epithelial cells

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25290-25296

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10.1074/JBC.M201466200

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277

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