Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E.
about
Hedgehog signaling overrides p53-mediated tumor suppression by activating Mdm2The magnitude of hedgehog signaling activity defines skin tumor phenotypeControlling cell division in yeast and animals: does size matter?How are the sizes of cells, organs, and bodies controlled?Differential range and activity of various forms of the Hedgehog proteinTargeted therapy for orbital and periocular basal cell carcinoma and squamous cell carcinomaHedgehog is a positive regulator of FGF signalling during embryonic tracheal cell migrationCyclin L2, a novel RNA polymerase II-associated cyclin, is involved in pre-mRNA splicing and induces apoptosis of human hepatocellular carcinoma cellsp65 Negatively regulates transcription of the cyclin E genepRb-mediated control of epithelial cell proliferation and Indian hedgehog expression in mouse intestinal developmentNovel Acylguanidine Derivatives Targeting Smoothened Induce Antiproliferative and Pro-Apoptotic Effects in Chronic Myeloid Leukemia CellsMice with a targeted mutation of patched2 are viable but develop alopecia and epidermal hyperplasiaIndian hedgehog stimulates periarticular chondrocyte differentiation to regulate growth plate length independently of PTHrPSnail induction is an early response to Gli1 that determines the efficiency of epithelial transformationGranulosa cell-expressed BMPR1A and BMPR1B have unique functions in regulating fertility but act redundantly to suppress ovarian tumor development.Ablation of Indian hedgehog in the murine uterus results in decreased cell cycle progression, aberrant epidermal growth factor signaling, and increased estrogen signalingPattern reorganization occurs independently of cell division during Drosophila wing disc regeneration in situ.Mechanism of G1 arrest in the Drosophila eye imaginal disc.Distinct roles of Shh and Fgf signaling in regulating cell proliferation during zebrafish pectoral fin development.In the absence of Sonic hedgehog, p53 induces apoptosis and inhibits retinal cell proliferation, cell-cycle exit and differentiation in zebrafishGli1 regulates the proliferation and differentiation of HSCs and myeloid progenitors.Evolutionarily conserved transcription factor Apontic controls the G1/S progression by inducing cyclin E during eye development.Targeting Hedgehog--a cancer stem cell pathwayThe Drosophila Netrin receptor frazzled/DCC functions as an invasive tumor suppressor.Gene expression profiling of the hedgehog signaling pathway in human meningiomas.Sonic hedgehog controls growth of external genitalia by regulating cell cycle kinetics.A critical role of autocrine sonic hedgehog signaling in human CD138+ myeloma cell survival and drug resistance.Inhibition of CK2α down-regulates Hedgehog/Gli signaling leading to a reduction of a stem-like side population in human lung cancer cellsSmarter drugs emerging in pancreatic cancer therapy.Differential involvement of Hedgehog signaling in butterfly wing and eyespot development.Activation of the Hedgehog pathway in chronic myelogeneous leukemia patients.A genetic screen for dominant modifiers of a cyclin E hypomorphic mutation identifies novel regulators of S-phase entry in Drosophila.The pineapple eye gene is required for survival of Drosophila imaginal disc cells.Patched homolog 1 gene mutation (p.G1093R) induces nevoid basal cell carcinoma syndrome and non-syndromic keratocystic odontogenic tumors: A case report.Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes.The homeodomain of Eyeless regulates cell growth and antagonizes the paired domain-dependent retinal differentiation functionCharacterization of Drosophila mini-me, a gene required for cell proliferation and survivalProteoglycan interactions with Sonic Hedgehog specify mitogenic responsesEnvironment, phenotype and genetics: risk factors associated with BCC of the skin.Lats2 modulates adipocyte proliferation and differentiation via hippo signaling.
P2860
Q24657777-8BEDE675-7B66-44AA-BE3C-C0AB3B06BA50Q24671053-4680584B-2634-4017-B5D0-F363ACC1184CQ24799131-49476F86-9E84-4A4B-B265-C8E907E53F69Q24800599-F70A78AC-BE9A-42FD-9DAF-FE94DADBC8A7Q24816458-1C3D35CB-B5B5-45C2-AF82-F6C1CC8EEF97Q26995961-8F5D4472-ECF8-4858-A700-E93369CC8218Q27313698-0BE3192E-36F4-4DAB-B0F2-2547AA5DA353Q28235123-A53444E5-A33D-4E6F-A766-23DF6380E249Q28395949-ACEEF26E-60EA-4FD6-A4DD-AE2EAE39C096Q28506890-FDC91EC0-994A-4306-8416-75D605CC6D35Q28550487-2C717170-2D2E-4336-B4A0-E3A111B17A55Q28591134-36142094-163E-4B7C-98CD-70C7A128C75DQ28592577-9D89C5E9-6CD4-45AC-94AF-F9E1D1DE5BC4Q29398901-C78309AD-1A98-4E98-AFF4-3B802DBF754AQ30432180-1A1946E7-A765-4884-AF26-EC1F210D3AAAQ30432806-73519F11-9C5D-4751-89F4-CC4D3CDF0706Q30542636-AB4FCA64-6CA5-49F8-8D4A-AB588CBC84FAQ33276683-47EB2364-9FA9-487A-ABAF-80C79F24CDD1Q33371378-9E2264B2-076E-4356-B8EC-0B70B6010784Q33735813-DDE18998-58C6-4B59-9897-AD8CC94BC682Q33754614-C5C175DB-1640-49B2-BEDB-F666A5F647C8Q33854045-E330219E-6438-4D3A-A803-B91D3992DEE7Q33925257-699B875D-B913-4900-93AB-F1703589EE8FQ33932269-424B1EC3-E63D-46A9-A9A7-4181A026B9F6Q33959137-6A6AE41A-53D9-445A-B04A-B336D77CA5DDQ34242717-9506B625-4C07-4B6D-B411-5DE10EB5CBE1Q34293000-60D5949D-7227-4137-B0EB-87EB37D67F15Q34328051-96573A3C-8DD2-4C4C-822A-2FE6910D25AAQ34410212-8930F0F8-6DC3-44B7-AE6C-01A2BBE89E7AQ34507234-D0B18577-FFE3-4DC0-9050-C021E752817AQ34547402-BD513A33-36F6-4797-AB6C-8E98C006CD3AQ34567130-2E8C2AF1-34F9-4B35-8990-EEEDD55FB029Q34619279-F71D4916-AE74-4E6D-AD81-F24B3B430CE0Q34640943-8E64CDB6-638A-4276-9C96-901CAB313F6FQ34667516-935EDAA5-4F73-4E25-85B3-CF8B39A9D08FQ34864796-2516BA08-FD8C-488A-8DF8-3E7E90203328Q34895638-0D6244A1-8E0F-4117-BF58-2CAD94C9B272Q34962804-36A5134C-909E-4C0E-935E-4EA1B74A9AFDQ34969264-BCA1D4DD-7A0E-449B-9C1C-79EEDAB145F2Q34972918-4C0E23D4-35F4-466E-9B33-DD36FEEDE656
P2860
Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E.
@en
Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E.
@nl
type
label
Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E.
@en
Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E.
@nl
prefLabel
Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E.
@en
Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E.
@nl
P2093
P2860
P356
P1433
P1476
Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E.
@en
P2093
Molly Duman-Scheel
Shijie Xin
P2860
P2888
P304
P356
10.1038/417299A
P407
P577
2002-05-01T00:00:00Z
P6179
1051168891