about
Enhanced anxiety, depressive-like behaviour and impaired recognition memory in mice with reduced expression of the vesicular glutamate transporter 1 (VGLUT1)Interactions between age, stress and insulin on cognition: implications for Alzheimer's diseaseStress-induced anhedonia is associated with an increase in Alzheimer's disease-related markers.Serotonergic therapies for cognitive symptoms in Alzheimer's disease: rationale and current status.Shared changes in gene expression in frontal cortex of four genetically modified mouse models of depression.Revealing the cerebral regions and networks mediating vulnerability to depression: oxidative metabolism mapping of rat brain.New 1-aryl-3-(4-arylpiperazin-1-yl)propane derivatives, with dual action at 5-HT1A serotonin receptors and serotonin transporter, as a new class of antidepressants.Neonatal stress affects vulnerability of cholinergic neurons and cognition in the rat: involvement of the HPA axis.Regulation of markers of synaptic function in mouse models of depression: chronic mild stress and decreased expression of VGLUT1.Sustained stress-induced changes in mice as a model for chronic depression.Antidepressant-like activity of VN2222, a serotonin reuptake inhibitor with high affinity at 5-HT1A receptors.Synthesis and molecular modeling of new 1-aryl-3-[4-arylpiperazin-1-yl]-1-propane derivatives with high affinity at the serotonin transporter and at 5-HT(1A) receptors.Altered expression of neuronal tryptophan hydroxylase-2 mRNA in the dorsal and median raphe nuclei of three genetically modified mouse models relevant to depression and anxiety.Nrf2 participates in depressive disorders through an anti-inflammatory mechanism.Effect of different 5-HT1A receptor antagonists in combination with paroxetine on expression of the immediate-early gene Arc in rat brain.Use of Arc expression as a molecular marker of increased postsynaptic 5-HT function after SSRI/5-HT1A receptor antagonist co-administration.Regulation of serotonin (5-HT) function by a VGLUT1 dependent glutamate pathway.Antidepressant drug treatment induces Arc gene expression in the rat brain.Glutamate receptor activation is involved in 5-HT2 agonist-induced Arc gene expression in the rat cortex.Increased vulnerability to depressive-like behavior of mice with decreased expression of VGLUT1.Effects of maternal separation on hypothalamic-pituitary-adrenal responses, cognition and vulnerability to stress in adult female rats.Evidence for increased expression of the vesicular glutamate transporter, VGLUT1, by a course of antidepressant treatment.Long-lasting behavioral effects and recognition memory deficit induced by chronic mild stress in mice: effect of antidepressant treatment.Chronic mild stress and imipramine treatment elicit opposite changes in behavior and in gene expression in the mouse prefrontal cortex.SIRT2 inhibition reverses anhedonia in the VGLUT1+/- depression model.SIRT2 inhibition modulate glutamate and serotonin systems in the prefrontal cortex and induces antidepressant-like action.Chronic stress and antidepressant induced changes in Hdac5 and Sirt2 affect synaptic plasticity.Venlafaxine reverses decreased proliferation in the subventricular zone in a rat model of early life stress.Cognitive impairment associated to HPA axis hyperactivity after maternal separation in rats.Stress contributes to the development of central insulin resistance during aging: implications for Alzheimer's disease.Social vs. environmental stress models of depression from a behavioural and neurochemical approach.Chronic social defeat stress model: behavioral features, antidepressant action, and interaction with biological risk factors.Sildenafil Decreases BACE1 and Cathepsin B Levels and Reduces APP Amyloidogenic Processing in the SAMP8 Mouse.Effects of neonatal stress on markers of synaptic plasticity in the hippocampus: implications for spatial memory.Down-regulation of glutamatergic terminals (VGLUT1) driven by Aβ in Alzheimer's disease.Long lasting effects of early-life stress on glutamatergic/GABAergic circuitry in the rat hippocampus.Chronic stress and impaired glutamate function elicit a depressive-like phenotype and common changes in gene expression in the mouse frontal cortex.Nucleocytoplasmic export of HDAC5 and SIRT2 downregulation: two epigenetic mechanisms by which antidepressants enhance synaptic plasticity markersDesign, synthesis and biological evaluation of new 3-[(4-aryl)piperazin-1-yl]-1-arylpropane derivatives as potential antidepressants with a dual mode of action: serotonin reuptake inhibition and 5-HT1A receptor antagonismCerebral oxidative metabolism mapping in four genetic mouse models of anxiety and mood disorders
P50
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P50
description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Rosa M Tordera
@ast
Rosa M Tordera
@en
Rosa M Tordera
@es
Rosa M Tordera
@nl
Rosa M Tordera
@sl
type
label
Rosa M Tordera
@ast
Rosa M Tordera
@en
Rosa M Tordera
@es
Rosa M Tordera
@nl
Rosa M Tordera
@sl
prefLabel
Rosa M Tordera
@ast
Rosa M Tordera
@en
Rosa M Tordera
@es
Rosa M Tordera
@nl
Rosa M Tordera
@sl
P1053
K-6353-2017
P106
P21
P31
P3829
P496
0000-0002-3564-4135