Negative epistasis between beneficial mutations in an evolving bacterial population.
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Genome features of "Dark-fly", a Drosophila line reared long-term in a dark environmentGenome-scale engineering for systems and synthetic biologyElucidating the molecular architecture of adaptation via evolve and resequence experimentsWhat can we learn from fitness landscapes?The causes of epistasisThe spectrum of adaptive mutations in experimental evolutionTowards the identification of the loci of adaptive evolutionDoes your gene need a background check? How genetic background impacts the analysis of mutations, genes, and evolutionConcerted evolution of life stage performances signals recent selection on yeast nitrogen use.Genomic investigations of evolutionary dynamics and epistasis in microbial evolution experimentsSystems biology of cancer: entropy, disorder, and selection-driven evolution to independence, invasion and "swarm intelligence"Bacterial adaptation through loss of functionRecombination accelerates adaptation on a large-scale empirical fitness landscape in HIV-1Steering Evolution with Sequential Therapy to Prevent the Emergence of Bacterial Antibiotic ResistanceStrong Selection Significantly Increases Epistatic Interactions in the Long-Term Evolution of a ProteinDisentangling genetic and epigenetic determinants of ultrafast adaptationParallel and Divergent Evolutionary Solutions for the Optimization of an Engineered Central Metabolism in Methylobacterium extorquens AM1Should tissue structure suppress or amplify selection to minimize cancer risk?Reverse evolution leads to genotypic incompatibility despite functional and active site convergenceThe Valley-of-Death: reciprocal sign epistasis constrains adaptive trajectories in a constant, nutrient limiting environmentMolecular Clock of Neutral Mutations in a Fitness-Increasing Evolutionary ProcessAdaptation, Clonal Interference, and Frequency-Dependent Interactions in a Long-Term Evolution Experiment with Escherichia coliContingency and entrenchment in protein evolution under purifying selectionThe functional basis of adaptive evolution in chemostatsGenome dynamics during experimental evolutionEpistasis can accelerate adaptive diversification in haploid asexual populationsExperimental evolution of an alternating uni- and multicellular life cycle in Chlamydomonas reinhardtii.The evolutionary time machine: using dormant propagules to forecast how populations can adapt to changing environmentsCancer in light of experimental evolutionThe mystery of missing heritability: Genetic interactions create phantom heritabilityWidespread Genetic Incompatibilities between First-Step Mutations during Parallel Adaptation of Saccharomyces cerevisiae to a Common EnvironmentDetecting High-Order Epistasis in Nonlinear Genotype-Phenotype MapsDeleterious Passengers in Adapting PopulationsCoevolution with bacteriophages drives genome-wide host evolution and constrains the acquisition of abiotic-beneficial mutations.In vitro selection of miltefosine resistance in promastigotes of Leishmania donovani from Nepal: genomic and metabolomic characterization.Adaptive walks on the fitness landscape of musicInteraction-based feature selection and classification for high-dimensional biological dataNetwork-Based Analysis of eQTL Data to Prioritize Driver Mutations.Fisher's geometrical model emerges as a property of complex integrated phenotypic networksEpistatically interacting substitutions are enriched during adaptive protein evolution
P2860
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P2860
Negative epistasis between beneficial mutations in an evolving bacterial population.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh-hant
name
Negative epistasis between beneficial mutations in an evolving bacterial population.
@en
Negative epistasis between beneficial mutations in an evolving bacterial population.
@nl
type
label
Negative epistasis between beneficial mutations in an evolving bacterial population.
@en
Negative epistasis between beneficial mutations in an evolving bacterial population.
@nl
prefLabel
Negative epistasis between beneficial mutations in an evolving bacterial population.
@en
Negative epistasis between beneficial mutations in an evolving bacterial population.
@nl
P2093
P2860
P356
P1433
P1476
Negative epistasis between beneficial mutations in an evolving bacterial population.
@en
P2093
Aisha I Khan
Dominique Schneider
Duy M Dinh
Tim F Cooper
P2860
P304
P356
10.1126/SCIENCE.1203801
P407
P577
2011-06-01T00:00:00Z