Low density of sigma1 receptors in early Alzheimer's disease. - Wikidata - awgldk - TriplyDB

Low density of sigma1 receptors in early Alzheimer's disease.

Low density of sigma1 receptors in early Alzheimer's disease.

http://www.wikidata.org/entity/Q44014199

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Recent Advances in Neurogenic Small Molecules as Innovative Treatments for Neurodegenerative Diseases Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity Sigma-1 receptor chaperones in neurodegenerative and psychiatric disorders The oligomeric states of the purified sigma-1 receptor are stabilized by ligands.Roles of sigma-1 receptors in Alzheimer's disease.Targeting ligand-operated chaperone sigma-1 receptors in the treatment of neuropsychiatric disorders.Pharmacological stimulation of sigma-1 receptors has neurorestorative effects in experimental parkinsonism.Fluorescent derivatives of σ receptor ligand 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) as a tool for uptake and cellular localization studies in pancreatic tumor cells.Sigma-1 receptor regulates Tau phosphorylation and axon extension by shaping p35 turnover via myristic acid.The sigma-1 receptor mediates the beneficial effects of pridopidine in a mouse model of Huntington disease Sigma-2 receptor agonist derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) induce cell death via mitochondrial superoxide production and caspase activation in pancreatic cancer.Subcellular localization of the sigma-1 receptor in retinal neurons - an electron microscopy study.The sigma-1 receptor: roles in neuronal plasticity and disease Preface.Myristic acid hitchhiking on sigma-1 receptor to fend off neurodegeneration.Sigma1 receptors inhibit store-operated Ca2+ entry by attenuating coupling of STIM1 to Orai1 Modulation of the endoplasmic reticulum-mitochondria interface in Alzheimer's disease and related models.Insights into the Sigma-1 receptor chaperone's cellular functions: a microarray report.Sigma receptors [σRs]: biology in normal and diseased states Structure activity relationship study of benzo[d]thiazol-2(3H)one based σ receptor ligands Steroid hormones affect binding of the sigma ligand 11C-SA4503 in tumour cells and tumour-bearing rats The pharmacology of sigma-1 receptors.Development of PET radiopharmaceuticals and their clinical applications at the Positron Medical Center.The development of radiotracers for imaging sigma (σ) receptors in the central nervous system (CNS) using positron emission tomography (PET).Pharmacokinetic and pharmacodynamic evaluation of donepezil for the treatment of Alzheimer's disease.Role of Sigma-1 Receptor in Cocaine Abuse and Neurodegenerative Disease.Sigma-1 Receptors and Neurodegenerative Diseases: Towards a Hypothesis of Sigma-1 Receptors as Amplifiers of Neurodegeneration and Neuroprotection.Role of σ1 Receptors in Learning and Memory and Alzheimer's Disease-Type Dementia.Mitochondria-Associated Membranes (MAMs): Overview and Its Role in Parkinson's Disease.Sigma-1 receptor agonist PRE084 is protective against mutant huntingtin-induced cell degeneration: involvement of calpastatin and the NF-κB pathway.Sigma-1 (σ1) Receptor in Memory and Neurodegenerative Diseases.2-Aminopyridine derivatives as potential σ(2) receptor antagonists.Loss of Sigma-1 Receptor Chaperone Promotes Astrocytosis and Enhances the Nrf2 Antioxidant Defense.A direct interaction between the sigma-1 receptor and the hERG voltage-gated K+ channel revealed by atomic force microscopy and homogeneous time-resolved fluorescence (HTRF®).New positron emission tomography (PET) radioligand for imaging σ-1 receptors in living subjects.Chiral resolution of serial potent and selective σ1 ligands and biological evaluation of (-)-[18F]TZ3108 in rodent and the nonhuman primate brain.Are sigma receptor modulators a weapon against multiple sclerosis disease?Quantification of highly selective sigma-1 receptor antagonist CM304 using liquid chromatography tandem mass spectrometry and its application to a pre-clinical pharmacokinetic study.Beyond symptomatic effects: potential of donepezil as a neuroprotective agent and disease modifier in Alzheimer's disease.Synthesis and evaluation of a (18) F-labeled 4-phenylpiperidine-4-carbonitrile radioligand for σ1 receptor imaging.

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P2860

Low density of sigma1 receptors in early Alzheimer's disease.

http://www.wikidata.org/entity/Q44014199

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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name

Low density of sigma1 receptors in early Alzheimer's disease.

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Low density of sigma1 receptors in early Alzheimer's disease.

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type

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Low density of sigma1 receptors in early Alzheimer's disease.

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Low density of sigma1 receptors in early Alzheimer's disease.

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prefLabel

Low density of sigma1 receptors in early Alzheimer's disease.

@en

Low density of sigma1 receptors in early Alzheimer's disease.

@nl

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Annals of Nuclear Medicine

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Low density of sigma1 receptors in early Alzheimer's disease.

@en

P2093

Kazunori Kawamura

http://www.w3.org/2001/XMLSchema#string

Kei-ichi Oda

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Kenji Ishii

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Kiichi Ishiwata

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Masahiro Mishina

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Masashi Ohyama

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Shin Kitamura

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Shiro Kobayashi

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Toru Sasaki

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Yasuo Katayama

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P2860

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

Steroid binding at sigma receptors suggests a link between endocrine, nervous, and immune systems.

Protein markers for Alzheimer disease in the frontal cortex and cerebellum.

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151-156

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10.1007/S12149-007-0094-Z

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3

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