In vitro mass production of human erythroid cells from the blood of normal donors and of thalassemic patients.
about
A highly conserved SOX6 double binding site mediates SOX6 gene downregulation in erythroid cellsConcise review: stem cell-derived erythrocytes as upcoming players in blood transfusionManufacturing blood ex vivo: a futuristic approach to deal with the supply and safety concernsEx vivo generation of fully mature human red blood cells from hematopoietic stem cellsGlobal increase in replication fork speed during a p57KIP2-regulated erythroid cell fate switchRecovery and Biodistribution of Ex Vivo Expanded Human Erythroblasts Injected into NOD/SCID/IL2Rγ miceErythroid progenitor cells expanded from peripheral blood without mobilization or preselection: molecular characteristics and functional competence.β-globin gene transfer to human bone marrow for sickle cell disease.EPO receptor gain-of-function causes hereditary polycythemia, alters CD34 cell differentiation and increases circulating endothelial precursors.Transcriptional silencing of {gamma}-globin by BCL11A involves long-range interactions and cooperation with SOX6.A zinc-finger transcriptional activator designed to interact with the gamma-globin gene promoters enhances fetal hemoglobin production in primary human adult erythroblastsProof of principle for transfusion of in vitro-generated red blood cells.hsa-miR-503 is downregulated in β thalassemia major.Erythropoiesis: development and differentiation.Therapeutic levels of fetal hemoglobin in erythroid progeny of β-thalassemic CD34+ cells after lentiviral vector-mediated gene transfer.GABP controls a critical transcription regulatory module that is essential for maintenance and differentiation of hematopoietic stem/progenitor cells.A synthetic model of human beta-thalassemia erythropoiesis using CD34+ cells from healthy adult donors.The dominant negative β isoform of the glucocorticoid receptor is uniquely expressed in erythroid cells expanded from polycythemia vera patients.HIV-1 Nef impairs key functional activities in human macrophages through CD36 downregulation.The role of glucocorticoid receptor (GR) polymorphisms in human erythropoiesis.Humanized culture medium for clinical expansion of human erythroblasts.The new self-inactivating lentiviral vector for thalassemia gene therapy combining two HPFH activating elements corrects human thalassemic hematopoietic stem cells.Stem cell-derived erythrocytes as upcoming players in blood transfusion.Krüppel-Like Transcription Factor KLF1 Is Required for Optimal γ- and β-Globin Expression in Human Fetal Erythroblasts.Correction of beta-thalassemia major by gene transfer in haematopoietic progenitors of pediatric patients.Ex vivo-generated CD36+ erythroid progenitors are highly permissive to human parvovirus B19 replicationDexamethasone targeted directly to macrophages induces macrophage niches that promote erythroid expansion.Novel, high-yield red blood cell production methods from CD34-positive cells derived from human embryonic stem, yolk sac, fetal liver, cord blood, and peripheral bloodTranscriptomic and phospho-proteomic analyzes of erythroblasts expanded in vitro from normal donors and from patients with polycythemia vera.Interaction between the glucocorticoid and erythropoietin receptors in human erythroid cellsPolyurethane scaffolds seeded with CD34(+) cells maintain early stem cells whilst also facilitating prolonged egress of haematopoietic progenitors.NF-E2 overexpression delays erythroid maturation and increases erythrocyte production.Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiationMononuclear cells from a rare blood donor, after freezing under good manufacturing practice conditions, generate red blood cells that recapitulate the rare blood phenotypeEx-vivo expansion of red blood cells: how real for transfusion in humans?Molecular mechanisms of pathology and treatment in Diamond Blackfan Anaemia.Concise review: production of cultured red blood cells from stem cells.Concise review: stem cell-based approaches to red blood cell production for transfusion.A genomic analysis of RNA polymerase II modification and chromatin architecture related to 3' end RNA polyadenylation.Human fetal liver: an in vitro model of erythropoiesis.
P2860
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P2860
In vitro mass production of human erythroid cells from the blood of normal donors and of thalassemic patients.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
In vitro mass production of hu ...... s and of thalassemic patients.
@en
In vitro mass production of hu ...... s and of thalassemic patients.
@nl
type
label
In vitro mass production of hu ...... s and of thalassemic patients.
@en
In vitro mass production of hu ...... s and of thalassemic patients.
@nl
prefLabel
In vitro mass production of hu ...... s and of thalassemic patients.
@en
In vitro mass production of hu ...... s and of thalassemic patients.
@nl
P2093
P50
P356
P1476
In vitro mass production of hu ...... s and of thalassemic patients.
@en
P2093
Anna Rita Migliaccio
Liliana Maccioni
Renzo Galanello
Thalia Papayannopoulou
Viviana di Giacomo
P304
P356
10.1006/BCMD.2002.0502
P577
2002-03-01T00:00:00Z