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Inhibition of retrograde transport modulates misfolded protein accumulation and clearance in motoneuron diseases.Rotenone upregulates alpha-synuclein and myocyte enhancer factor 2D independently from lysosomal degradation inhibition.Impairment of glutamate transport and increased vulnerability to oxidative stress in neuroblastoma SH-SY5Y cells expressing a Cu,Zn superoxide dismutase typical of familial amyotrophic lateral sclerosis.Leber hereditary optic neuropathy mtDNA mutations disrupt glutamate transport in cybrid cell lines.Glutamate transporters in platelets: EAAT1 decrease in aging and in Alzheimer's disease.Valproate Treatment in an ALS Patient Carrying a c.194G>A Spastin Mutation and SMN2 Homozygous Deletion.Mitochondrial dysfunction due to mutant copper/zinc superoxide dismutase associated with amyotrophic lateral sclerosis is reversed by N-acetylcysteine.Reduced expression of the chaperone-mediated autophagy carrier hsc70 protein in lymphomonocytes of patients with Parkinson's disease.Rotenone down-regulates HSPA8/hsc70 chaperone protein in vitro: A new possible toxic mechanism contributing to Parkinson's disease.Lack of evidence for oxidative stress in sporadic amyotrophic lateral sclerosis fibroblasts.Peripheral cytokine release in Alzheimer patients: correlation with disease severity.Huntington's disease and HDACi: would sulpiride and valproate be of therapeutic value?Whole-blood global DNA methylation is increased in amyotrophic lateral sclerosis independently of age of onset.Pravastatin acute neuroprotective effects depend on blood brain barrier integrity in experimental cerebral ischemia.Acute lipophilicity-dependent effect of intravascular simvastatin in the early phase of focal cerebral ischemia.Valproate and HDAC inhibition: a new epigenetic strategy to mitigate phenotypic severity in ALS?Nerve growth factor and transforming growth factor-beta serum levels in acute stroke patients. Possible involvement of neurotrophins in cerebrovascular disease.MEF2D and MEF2C pathways disruption in sporadic and familial ALS patients.Partial mitochondrial complex I inhibition induces oxidative damage and perturbs glutamate transport in primary retinal cultures. Relevance to Leber Hereditary Optic Neuropathy (LHON).A panel of macroautophagy markers in lymphomonocytes of patients with amyotrophic lateral sclerosisHSC70 expression is reduced in lymphomonocytes of sporadic ALS patients and contributes to TDP-43 accumulation
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հետազոտող
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Gessica Sala
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Gessica Sala
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Gessica Sala
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Gessica Sala
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Gessica Sala
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Gessica Sala
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Gessica Sala
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Gessica Sala
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Gessica Sala
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Gessica Sala
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Gessica Sala
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Gessica Sala
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Gessica Sala
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Gessica Sala
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Gessica Sala
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0000-0003-3573-7523