The EBNA-3 gene family proteins disrupt the G2/M checkpoint. - Wikidata - awgldk - TriplyDB

The EBNA-3 gene family proteins disrupt the G2/M checkpoint.

The EBNA-3 gene family proteins disrupt the G2/M checkpoint.

http://www.wikidata.org/entity/Q44036145

about

Role of EBNA-3 Family Proteins in EBV Associated B-cell Lymphomagenesis Cyclin A/cdk2 coordinates centrosomal and nuclear mitotic events Kaposi sarcoma herpes virus latency associated nuclear antigen protein release the G2/M cell cycle blocks by modulating ATM/ATR mediated checkpoint pathway Epstein-Barr virus nuclear antigen 2 (EBNA2) gene deletion is consistently linked with EBNA3A, -3B, and -3C expression in Burkitt's lymphoma cells and with increased resistance to apoptosis.Upregulation of the cell-cycle regulator RGC-32 in Epstein-Barr virus-immortalized cells.Epstein-Barr virus Latent Membrane Protein LMP1 reduces p53 protein levels independent of the PI3K-Akt pathway.Epstein-Barr virus nuclear antigen 3A promotes cellular proliferation by repression of the cyclin-dependent kinase inhibitor p21WAF1/CIP1.Modulation of enhancer looping and differential gene targeting by Epstein-Barr virus transcription factors directs cellular reprogramming.The ATM/ATR signaling effector Chk2 is targeted by Epstein-Barr virus nuclear antigen 3C to release the G2/M cell cycle block Viral manipulation of DNA repair and cell cycle checkpoints Nucleoside diphosphate kinase/Nm23 and Epstein-Barr virus.How does Epstein-Barr virus (EBV) complement the activation of Myc in the pathogenesis of Burkitt's lymphoma?Histone deacetylase inhibitors in the generation of the anti-tumour immune response.Deregulation of the cell cycle machinery by Epstein-Barr virus nuclear antigen 3C.Epstein-Barr virus EBNA-3C is targeted to and regulates expression from the bidirectional LMP-1/2B promoter.Downregulation of integrin receptor-signaling genes by Epstein-Barr virus EBNA 3C via promoter-proximal and -distal binding elements Epstein-barr virus-induced resistance to drugs that activate the mitotic spindle assembly checkpoint in Burkitt's lymphoma cells.Inhibition of S/G2 phase CDK4 reduces mitotic fidelity.Epstein-Barr virus selectively deregulates DNA damage responses in normal B cells but has no detectable effect on regulation of the tumor suppressor p53.Epstein-Barr virus lytic replication elicits ATM checkpoint signal transduction while providing an S-phase-like cellular environment.Defective cell cycle checkpoints as targets for anti-cancer therapies.Gene variations of Epstein-Barr virus nuclear antigen 3A in nasopharyngeal carcinomas, gastric carcinomas and healthy carriers in northern China.Therapeutic Strategies against Epstein-Barr Virus-Associated Cancers Using Proteasome Inhibitors.Pumilio directs deadenylation-associated translational repression of the cyclin-dependent kinase 1 activator RGC-32.Counteracting survival functions of EBNA3C in Epstein-Barr virus (EBV)-driven lymphoproliferative diseases by combination of SAHA and bortezomib.

P2860

Q26752541-649120FE-D1BD-4819-B48E-201013EAEAD9 Q28274303-75D80B90-45F2-4C57-91CA-A6A8643CC5B5 Q28540116-29B64364-BD8C-4157-9C24-6DE11E0DC033 Q33911843-E4FEC3A0-4A55-42D7-A29E-115662E26E13 Q34097970-8D623A6C-2038-4603-AD6D-6D65CCDD5869 Q34106993-35E9CEE0-709C-42D3-BE5A-0CEA99D86C38 Q34283174-76C066D3-303C-4E6F-837A-7F65682B742C Q34998243-5584CED1-2C43-4D9A-A738-3BB5BEF13C38 Q35857290-05AC3905-49A7-4613-987C-8CC2A54FEF5F Q37301053-D9A0EEBE-7779-42CE-8624-70A04CE51DB6 Q37468665-CF370797-87DD-4515-87E1-4C346CA3CF3D Q37563700-3CA7BA3A-6C99-4977-AA94-9CA3988A4634 Q37953826-DE403C2F-33E3-4005-A966-E25E6957DDC9 Q38337443-D2E7FFDC-234B-4EEA-AAEC-73296C611157 Q39306073-0938D328-19AE-4976-98EB-710B4A441BBE Q39392125-B5CB5144-FC30-4D8A-95F8-0A4CB0FBF221 Q40221184-9854F795-E7FA-44F7-86F6-81A18CC437E9 Q40316740-1A839274-351E-4ACD-94B7-F1518230C9C9 Q40333155-26BDFAB5-7B94-4407-A4F7-79CD930A2627 Q40478598-A6C4DE76-DDF4-46A9-A243-474AC98637A6 Q40794273-7F7F67EA-6DD3-4A8D-8E0E-AF03BA3D189E Q44547945-0E0CE8C2-10BC-4C22-A009-D4EE424B623F Q45324502-A8EC1B5B-D0A9-4AAE-A250-9FC6A1E08C21 Q47547593-D7DB9E15-ED63-485D-BBBF-1458CAF63EE7 Q55221402-C941CB38-0717-40B8-B5E8-A317A0F53C0D

P2860

The EBNA-3 gene family proteins disrupt the G2/M checkpoint.

http://www.wikidata.org/entity/Q44036145

description

2004 nî lūn-bûn

@nan

2004年の論文

@ja

2004年学术文章

@wuu

2004年学术文章

@zh-cn

2004年学术文章

@zh-hans

2004年学术文章

@zh-my

2004年学术文章

@zh-sg

2004年學術文章

@yue

2004年學術文章

@zh

2004年學術文章

@zh-hant

name

The EBNA-3 gene family proteins disrupt the G2/M checkpoint.

@en

The EBNA-3 gene family proteins disrupt the G2/M checkpoint.

@nl

type

label

The EBNA-3 gene family proteins disrupt the G2/M checkpoint.

@en

The EBNA-3 gene family proteins disrupt the G2/M checkpoint.

@nl

prefLabel

The EBNA-3 gene family proteins disrupt the G2/M checkpoint.

@en

The EBNA-3 gene family proteins disrupt the G2/M checkpoint.

@nl

P1433

Q44036145-F7458A20-F4BB-4DF6-A184-98F41961D1CD

P1476

Q44036145-0F438073-30C3-4D3A-B401-9673242A9B39

P2093

Q44036145-4F6E7028-CDEF-4259-89A1-D9E682F67555

Q44036145-BE6283A0-D5F0-4D42-BD96-3AC7EFBCDDA3

Q44036145-CAF74273-0771-4D89-A536-83A8FA84362A

Q44036145-D6ABAE02-75A3-4473-9175-C44E3F0DEF4D

Q44036145-F38DDD86-558E-429A-B5E4-2A2C9E4EBFD6

P2860

Q44036145-153E7A00-952F-483B-A23C-6C7C8E45AF1F

Q44036145-17537BE8-B674-4E68-99A0-10B602877162

Q44036145-197F4329-4811-4298-B445-AD97FAC783C5

Q44036145-1EE0C27E-621E-4459-B1F1-85C69002D61E

Q44036145-23A6FAFC-1D96-46A8-9730-062297ADCE09

Q44036145-42B0CAC7-1FF1-4629-ABFE-A03BEDB47A36

Q44036145-498FE591-EAEA-474F-8625-81BD05794995

Q44036145-531CDEDA-D914-4009-B514-F06008302B22

Q44036145-558EF0D1-FBED-4663-94F0-FF4B7FB6EB55

Q44036145-6002025F-A5D7-442F-B5FF-04F23975FA0E

P2888

Q44036145-4006E0FC-08FB-4081-B9C7-C1863D3F01DC

P304

Q44036145-D4F04B0C-9C09-4D1D-A399-A46544D89143

P31

Q44036145-0B980057-0FFC-4D64-889F-B426CEE0E71E

P356

Q44036145-22E88679-CA6F-4D57-BF96-3D4E4BA73D1B

P407

Q44036145-0CFFAF4B-A247-4FAD-9C81-9FC51A8A6829

P433

Q44036145-F383D9C2-38D9-4997-96FC-A5F30E09907F

P478

Q44036145-6EA418F7-09C8-49A4-90AB-2DF8EBC01F60

P50

Q44036145-BA4AABF4-167C-4310-9627-673A931BE2D6

P577

Q44036145-89E667EB-D1D2-40CD-A579-0D210AA99DA4

P5875

Q44036145-A9D65800-1352-4A79-9DB2-7CC3053CB520

P698

Q44036145-391E185B-2496-47B2-8C9E-0BD1AA8D38CC

P356

P1433

P1476

The EBNA-3 gene family proteins disrupt the G2/M checkpoint.

@en

P2093

Brian Gabrielli

http://www.w3.org/2001/XMLSchema#string

James Flanagan

http://www.w3.org/2001/XMLSchema#string

Kenia G Krauer

http://www.w3.org/2001/XMLSchema#string

Marion Buck

http://www.w3.org/2001/XMLSchema#string

Tom B Sculley

http://www.w3.org/2001/XMLSchema#string

P2860

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

Characterization of DP103, a novel DEAD box protein that binds to the Epstein-Barr virus nuclear proteins EBNA2 and EBNA3C

Cloning of cDNAs for M-phase phosphoproteins recognized by the MPM2 monoclonal antibody and determination of the phosphorylated epitope

S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe

The DNA damage response: putting checkpoints in perspective

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

The G2-phase DNA-damage checkpoint

Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

Caffeine inhibits the checkpoint kinase ATM

Cell cycle checkpoints: preventing an identity crisis

P2888

P304

1342-1353

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/SJ.ONC.1207253

http://www.w3.org/2001/XMLSchema#string

P407

P433

7

http://www.w3.org/2001/XMLSchema#string

P478

23

http://www.w3.org/2001/XMLSchema#string

P50

P577

2004-02-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

8925305

http://www.w3.org/2001/XMLSchema#string

P698

14716295

http://www.w3.org/2001/XMLSchema#string