Inhibition of allergic inflammation in the airways using aerosolized antisense to Syk kinase. - Wikidata - awgldk - TriplyDB

Inhibition of allergic inflammation in the airways using aerosolized antisense to Syk kinase.

Inhibition of allergic inflammation in the airways using aerosolized antisense to Syk kinase.

http://www.wikidata.org/entity/Q44050002

about

Functional classes of bronchial mucosa genes that are differentially expressed in asthma Delivery of RNAi Therapeutics to the Airways-From Bench to Bedside Activation of Syk by protein kinase C-delta regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via tyrosine phosphorylation of RelA/p65.A rat model of exercise-induced asthma: a nonspecific response to a specific immunogen.Syk tyrosine kinase participates in beta1-integrin signaling and inflammatory responses in airway epithelial cells.Eupatilin blocks mediator release via tyrosine kinase inhibition in activated guinea pig lung mast cells.Nanomedicine in pulmonary delivery Getting Syk: spleen tyrosine kinase as a therapeutic target.Frontline: Inhibition of allergen-induced pulmonary inflammation by the tripeptide feG: a mimetic of a neuro-endocrine pathway.A review of antisense therapeutic interventions for molecular biological targets in asthma.New asthma drugs acting on gene expression.Biochemical assessment of intracellular signal transduction pathways in eosinophils: implications for pharmacotherapy.Effects of nebulized ketamine on allergen-induced airway hyperresponsiveness and inflammation in actively sensitized Brown-Norway rats Targeting Syk as a treatment for allergic and autoimmune disorders.The immunoglobulin E receptor: expression and regulation.Syk Regulates Neutrophilic Airway Hyper-Responsiveness in a Chronic Mouse Model of Allergic Airways Inflammation.Spleen tyrosine kinase (Syk) as a novel target for allergic asthma and rhinitis.Liposomes in the treatment of inflammatory disorders.Antisense- and RNA interference-based therapeutic strategies in allergy.The future of antisense oligonucleotides in the treatment of respiratory diseases.Syk activation in dendritic cells is essential for airway hyperresponsiveness and inflammation.Inhibition of spleen tyrosine kinase prevents mast cell activation and airway hyperresponsiveness TIM-3 is not essential for development of airway inflammation induced by house dust mite antigens.Therapeutic prospect of Syk inhibitors.Emerging oligonucleotide therapies for asthma and chronic obstructive pulmonary disease.Gene therapy for allergic airway diseases.Design and development of antisense drugs.Pulmonary Delivery of siRNA via Polymeric Vectors as Therapies of Asthma Kinases as Novel Therapeutic Targets in Asthma and Chronic Obstructive Pulmonary Disease.Inhibitory effect of the branches of Hovenia dulcis Thunb. and its constituent pinosylvin on the activities of IgE-mediated mast cells and passive cutaneous anaphylaxis in mice.Homoisoflavanone prevents mast cell activation and allergic responses by inhibition of Syk signaling pathway.Oligonucleotide Therapy for Obstructive and Restrictive Respiratory Diseases.PRT062607 Achieves Complete Inhibition of the Spleen Tyrosine Kinase at Tolerated Exposures Following Oral Dosing in Healthy Volunteers Sustained activation of the tyrosine kinase Syk by antigen in mast cells requires local Ca2+ influx through Ca2+ release-activated Ca2+ channels.Involvement of Syk protein tyrosine kinase in LPS-induced responses in macrophages.Spleen tyrosine kinase inhibition blocks airway constriction and protects from Th2-induced airway inflammation and remodeling.Inhibition of spleen tyrosine kinase attenuates IgE-mediated airway contraction and mediator release in human precision cut lung slices.Antiinflammatory effects of genistein, a tyrosine kinase inhibitor, on a guinea pig model of asthma.The intratracheal administration of locked nucleic acid containing antisense oligonucleotides induced gene silencing and an immune-stimulatory effect in the murine lung.Inhibition of spleen tyrosine kinase attenuates allergen-mediated airway constriction.

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P2860

Inhibition of allergic inflammation in the airways using aerosolized antisense to Syk kinase.

http://www.wikidata.org/entity/Q44050002

description

2002 nî lūn-bûn

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2002年の論文

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年學術文章

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2002年學術文章

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name

Inhibition of allergic inflamm ...... lized antisense to Syk kinase.

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Inhibition of allergic inflamm ...... lized antisense to Syk kinase.

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type

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Inhibition of allergic inflamm ...... lized antisense to Syk kinase.

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Inhibition of allergic inflamm ...... lized antisense to Syk kinase.

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prefLabel

Inhibition of allergic inflamm ...... lized antisense to Syk kinase.

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Inhibition of allergic inflamm ...... lized antisense to Syk kinase.

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JIMMUNOL.169.2.1028

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Journal of Immunology

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Inhibition of allergic inflamm ...... lized antisense to Syk kinase.

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A Dean Befus

http://www.w3.org/2001/XMLSchema#string

Alan D Schreiber

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Deborah James

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Grant R Stenton

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Lakshmi Puttagunta

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Marina Ulanova

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Mark Gilchrist

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Moo-Kyung Kim

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René E Déry

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Shaheed Merani

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1028-1036

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scholarly article

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2002-07-01T00:00:00Z

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