CXCR4 chemokine receptors (CD184) and alpha4beta1 integrins mediate spontaneous migration of human CD34+ progenitors and acute myeloid leukaemia cells beneath marrow stromal cells (pseudoemperipolesis).
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VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic nicheExosomes: The Link between GPCR Activation and Metastatic Potential?MLL-rearranged acute lymphoblastic leukaemia stem cell interactions with bone marrow stroma promote survival and therapeutic resistance that can be overcome with CXCR4 antagonismHigh expression of the very late antigen-4 integrin independently predicts reduced risk of relapse and improved outcome in pediatric acute myeloid leukemia: a report from the children's oncology groupPlerixafor as a chemosensitizing agent in pediatric acute lymphoblastic leukemia: efficacy and potential mechanisms of resistance to CXCR4 inhibition.The N-terminal CEBPA mutant in acute myeloid leukemia impairs CXCR4 expressionProteomic profiling identifies distinct protein patterns in acute myelogenous leukemia CD34+CD38- stem-like cells.CXCR4 expression on pathogenic T cells facilitates their bone marrow infiltration in a mouse model of aplastic anemiaHigh VLA-4 expression is associated with adverse outcome and distinct gene expression changes in childhood B-cell precursor acute lymphoblastic leukemia at first relapse.Homing of cancer cells to the boneHierarchy of molecular-pathway usage in bone marrow homing and its shift by cytokines.POL5551, a novel and potent CXCR4 antagonist, enhances sensitivity to chemotherapy in pediatric ALLVery late antigen-4 function of myeloblasts correlates with improved overall survival for patients with acute myeloid leukemia.Dynamic chemotherapy-induced upregulation of CXCR4 expression: a mechanism of therapeutic resistance in pediatric AML.Anti-apoptotic ARC protein confers chemoresistance by controlling leukemia-microenvironment interactions through a NFκB/IL1β signaling network.The critical role of SDF-1/CXCR4 axis in cancer and cancer stem cells metastasis.The bone marrow microenvironment and leukemia: biology and therapeutic targeting.Crosstalk between Stem and Progenitor Cellular Mediators with Special Emphasis on Vasculogenesis.VLA-4 and CXCR4 expression levels show contrasting prognostic impact (favorable and unfavorable, respectively) in acute myeloid leukemia.Oxygen tension plays a critical role in the hematopoietic microenvironment in vitro.CXCR4 antagonists suppress small cell lung cancer progression.Modeling the marrow stem cell niche in vitro: is proximity the key to reproduction?Therapeutic Antibodies for Myeloid Neoplasms-Current Developments and Future Directions.Dependence of acute myeloid leukemia on adhesion within the bone marrow microenvironment.
P2860
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P2860
CXCR4 chemokine receptors (CD184) and alpha4beta1 integrins mediate spontaneous migration of human CD34+ progenitors and acute myeloid leukaemia cells beneath marrow stromal cells (pseudoemperipolesis).
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
CXCR4 chemokine receptors (CD1 ...... l cells (pseudoemperipolesis).
@en
CXCR4 chemokine receptors
@nl
type
label
CXCR4 chemokine receptors (CD1 ...... l cells (pseudoemperipolesis).
@en
CXCR4 chemokine receptors
@nl
prefLabel
CXCR4 chemokine receptors (CD1 ...... l cells (pseudoemperipolesis).
@en
CXCR4 chemokine receptors
@nl
P2093
P2860
P1476
CXCR4 chemokine receptors (CD1 ...... l cells (pseudoemperipolesis).
@en
P2093
Anne Dwenger
Dirk Behringer
Jan A Burger
Meike Burger
P2860
P304
P356
10.1046/J.1365-2141.2003.04466.X
P407
P577
2003-08-01T00:00:00Z