Both tissue inhibitors of metalloproteinases-1 (TIMP-1) and TIMP-2 activate Ras but through different pathways.
about
The tissue inhibitors of metalloproteinases (TIMPs): an ancient family with structural and functional diversitySilencing the hsp25 gene eliminates migration capability of the highly metastatic murine 4T1 breast adenocarcinoma cell.TIMP-1 Inhibits Apoptosis in Lung Adenocarcinoma Cells via Interaction with Bcl-2.Comparison of metalloproteinase protein and activity profiling.Prognostic significance of tissue inhibitor of metalloproteinase-1 in breast cancer.Tissue Inhibitor of Metalloproteinase-1: Actions beyond Matrix Metalloproteinase Inhibition.Growth-stimulatory activity of TIMP-2 is mediated through c-Src activation followed by activation of FAK, PI3-kinase/AKT, and ERK1/2 independent of MMP inhibition in lung adenocarcinoma cellsTissue inhibitors of metalloproteinases in cell signaling: metalloproteinase-independent biological activities.Neurogenic differentiation factor NeuroD confers protection against radiation-induced intestinal injury in mice.Biology and potential clinical implications of tissue inhibitor of metalloproteinases-1 in colorectal cancer treatment.Nuclear localization of catalytically active MMP-2 in endothelial cells and neurons.Tissue inhibitor of metalloproteinase-1 promotes NIH3T3 fibroblast proliferation by activating p-Akt and cell cycle progression.TIMP-1 is under regulation of the EGF signaling axis and promotes an aggressive phenotype in KRAS-mutated colorectal cancer cells: a potential novel approach to the treatment of metastatic colorectal cancer.Cytokine functions of TIMP-1.Tissue inhibitor of metalloproteinase-1 stimulates proliferation of human cancer cells by inhibiting a metalloproteinaseTIMP-1 overexpression in lung carcinoma enhances tumor kinetics and angiogenesis in brain metastasis.Enhanced migration of tissue inhibitor of metalloproteinase overexpressing hepatoma cells is attributed to gelatinases: relevance to intracellular signaling pathwaysTissue inhibitor of metalloproteinase 1 activates normal human granulocytes, protects them from apoptosis, and blocks their transmigration during inflammation.Tissue inhibitor of metalloproteinases-1 signalling pathway leading to erythroid cell survival.Chikungunya virus dissemination from the midgut of Aedes aegypti is associated with temporal basal lamina degradation during bloodmeal digestionOverexpression of endogenous TIMP-2 increases the proliferation of BeWo choriocarcinoma cells through the MAPK-signaling pathway.Neuroprotective effect of adenoviral-mediated gene transfer of TIMP-1 and -2 in ischemic brain injury.Comparative studies of tissue inhibitor of metalloproteinases-1 in plasma, serum and tumour tissue extracts from patients with primary colorectal cancer.Low expression of tissue inhibitor of metalloproteinases-1 (TIMP-1) in glioblastoma predicts longer patient survival.Relationship of biomarkers of extracellular matrix with myocardial function in Type 2 diabetes mellitus.The Many Facets of Metzincins and Their Endogenous Inhibitors: Perspectives on Ovarian Cancer Progression.
P2860
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P2860
Both tissue inhibitors of metalloproteinases-1 (TIMP-1) and TIMP-2 activate Ras but through different pathways.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Both tissue inhibitors of meta ...... ut through different pathways.
@en
Both tissue inhibitors of metalloproteinases-1
@nl
type
label
Both tissue inhibitors of meta ...... ut through different pathways.
@en
Both tissue inhibitors of metalloproteinases-1
@nl
prefLabel
Both tissue inhibitors of meta ...... ut through different pathways.
@en
Both tissue inhibitors of metalloproteinases-1
@nl
P2093
P1476
Both tissue inhibitors of meta ...... ut through different pathways.
@en
P2093
Kazushi Iwata
Kyoko Yamashita
Taro Hayakawa
P304
P356
10.1016/S0006-291X(02)00741-6
P407
P577
2002-08-01T00:00:00Z