Substrate-dependent, non-hyperbolic kinetics of pig brain prolyl oligopeptidase and its tight binding inhibition by JTP-4819.
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Beneficial effect of prolyl oligopeptidase inhibition on spatial memory in young but not in old scopolamine-treated ratsMolecular dynamics study of prolyl oligopeptidase with inhibitor in binding cavity.Biological evaluation of RBx-0128, a potent and selective dipeptidyl peptidase-IV inhibitor in type 2 diabetes genetic modelDistribution of prolyl oligopeptidase in human peripheral tissues and in ovarian and colorectal tumorsProlyl oligopeptidase and its role in the organism: attention to the most promising and clinically relevant inhibitors.Slow-binding inhibitors of prolyl oligopeptidase with different functional groups at the P1 site.Nature of action of Sitagliptin, the dipeptidyl peptidase-IV inhibitor in diabetic animals.Enhancement of fibrinolysis by inhibiting enzymatic cleavage of precursor α2-antiplasmin.Primary structure, recombinant expression and homology modelling of human brain prolyl oligopeptidase, an important therapeutic target in the treatment of neuropsychiatric diseases.Characterization of membrane-bound prolyl endopeptidase from brain.Fibroblast activation protein-α in fibrogenic disorders and cancer: more than a prolyl-specific peptidase?Brain pharmacokinetics of two prolyl oligopeptidase inhibitors, JTP-4819 and KYP-2047, in the rat.Sequential expression, activity and nuclear localization of prolyl oligopeptidase protein in the developing rat brain.
P2860
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P2860
Substrate-dependent, non-hyperbolic kinetics of pig brain prolyl oligopeptidase and its tight binding inhibition by JTP-4819.
description
2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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2002年学术文章
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@zh-hans
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name
Substrate-dependent, non-hyper ...... inding inhibition by JTP-4819.
@en
Substrate-dependent, non-hyper ...... inding inhibition by JTP-4819.
@nl
type
label
Substrate-dependent, non-hyper ...... inding inhibition by JTP-4819.
@en
Substrate-dependent, non-hyper ...... inding inhibition by JTP-4819.
@nl
prefLabel
Substrate-dependent, non-hyper ...... inding inhibition by JTP-4819.
@en
Substrate-dependent, non-hyper ...... inding inhibition by JTP-4819.
@nl
P2093
P50
P1476
Substrate-dependent, non-hyper ...... binding inhibition by JTP-4819
@en
P2093
Jarkko I Venäläinen
Jukka Gynther
Risto O Juvonen
P304
P356
10.1016/S0006-2952(02)01184-X
P407
P577
2002-08-01T00:00:00Z