Molecular crowding stabilizes both the intrinsically disordered calcium-free state and the folded calcium-bound state of a repeat in toxin (RTX) protein.
about
Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs)What macromolecular crowding can do to a proteinStructural models of intrinsically disordered and calcium-bound folded states of a protein adapted for secretionDisorder-to-order transition in the CyaA toxin RTX domain: implications for toxin secretionThe Redox State Regulates the Conformation of Rv2466c to Activate the Antitubercular Prodrug TP053.Calcium, acylation, and molecular confinement favor folding of Bordetella pertussis adenylate cyclase CyaA toxin into a monomeric and cytotoxic formThe Differential Response of Proteins to Macromolecular CrowdingReconstituting Intracellular Vesicle Fusion Reactions: The Essential Role of Macromolecular CrowdingDigested disorder: Quarterly intrinsic disorder digest (July-August-September, 2013)Molecular Modeling of the Catalytic Domain of CyaA Deepened the Knowledge of Its Functional Dynamics.Negatively charged residues of the segment linking the enzyme and cytolysin moieties restrict the membrane-permeabilizing capacity of adenylate cyclase toxin.Stability, structural and functional properties of a monomeric, calcium-loaded adenylate cyclase toxin, CyaA, from Bordetella pertussis.Allosteric activation of Bordetella pertussis adenylyl cyclase by calmodulin: molecular dynamics and mutagenesis studiesAn optimized strategy to measure protein stability highlights differences between cold and hot unfolded states.Characterization of a membrane-active peptide from the Bordetella pertussis CyaA toxin.Membrane-Active Properties of an Amphitropic Peptide from the CyaA Toxin Translocation Region.SEC-SAXS and HDX-MS: A powerful combination. The case of the calcium-binding domain of a bacterial toxin.Calmodulin fishing with a structurally disordered bait triggers CyaA catalysis.Mechanistic insights into the allosteric regulation of bacterial ADP-glucose pyrophosphorylases.
P2860
Q26823798-7579C980-6057-4003-BA25-237F1E50C484Q27012942-67E4E88F-ED28-4839-AD48-6A799CD69460Q27308665-5B7ABFEE-A77A-4961-A326-8D37D2173EE4Q28083580-C16F3E78-91E0-46A6-894A-88A8C4A11C7EQ30692645-50A2DCF1-1BD3-4D3F-B55D-FD1FAE14FB1BQ35260287-4CA07862-2534-499E-B66D-2E4F75F8CFC3Q36089426-EDFF5850-74BB-4EA0-B4A6-4DC3E20509C4Q36263474-F21B67DF-54AB-4D2A-B8A7-94443F99F093Q39148653-74E20D1C-69EB-4451-BB25-B69C44532334Q39411650-3A7F7F68-6164-4B25-8D76-7615CF87FE65Q40991060-08C17566-20AE-4AE4-9B5E-3A77115009ACQ41882978-5F19E3BE-4BD1-4622-908E-BAD9E452E9C6Q41891782-C1F4E69D-83EB-4AEF-8A15-534F1A58C512Q42229952-0A72C94B-504E-45D5-8DDA-142AFC31FF31Q42917720-6FEAD8FE-2CD4-4998-8354-C458E2D1C475Q47128421-9CF1E2B6-A11A-4BE3-A115-273CABE14A6CQ47997009-26C6FBAD-34C0-4841-B28A-0EC39094273FQ48331099-B06367BF-615E-4A7E-913B-60DA00348117Q51128457-2E7BD6F3-3000-4EB4-BD0C-1E158AC19CAD
P2860
Molecular crowding stabilizes both the intrinsically disordered calcium-free state and the folded calcium-bound state of a repeat in toxin (RTX) protein.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh-hant
name
Molecular crowding stabilizes ...... repeat in toxin (RTX) protein.
@en
Molecular crowding stabilizes ...... und state of a repeat in toxin
@nl
type
label
Molecular crowding stabilizes ...... repeat in toxin (RTX) protein.
@en
Molecular crowding stabilizes ...... und state of a repeat in toxin
@nl
prefLabel
Molecular crowding stabilizes ...... repeat in toxin (RTX) protein.
@en
Molecular crowding stabilizes ...... und state of a repeat in toxin
@nl
P2093
P356
P1476
Molecular crowding stabilizes ...... repeat in toxin (RTX) protein
@en
P2093
Ana-Cristina Sotomayor-Pérez
Audrey Hessel
Orso Subrini
P304
11929-11934
P356
10.1021/JA404790F
P407
P577
2013-07-31T00:00:00Z