Insights into MLC pathogenesis: GlialCAM is an MLC1 chaperone required for proper activation of volume-regulated anion currents.
about
Protein homeostasis at the plasma membraneGlialCAM, a CLC-2 Cl(-) channel subunit, activates the slow gate of CLC chloride channels.HepaCAM associates with connexin 43 and enhances its localization in cellular junctions.Regulatory-auxiliary subunits of CLC chloride channel-transport proteins.MLC1 protein: a likely link between leukodystrophies and brain channelopathies.Structural determinants of interaction, trafficking and function in the ClC-2/MLC1 subunit GlialCAM involved in leukodystrophy.Megalencephalic leukoencephalopathy with subcortical cysts protein 1 regulates glial surface localization of GLIALCAM from fish to humans.Megalencephalic leukoencephalopathy with cysts: the Glialcam-null mouse modelLeukoencephalopathy-causing CLCN2 mutations are associated with impaired Cl- channel function and trafficking.Functional analyses of mutations in HEPACAM causing megalencephalic leukoencephalopathy.Depolarization causes the formation of a ternary complex between GlialCAM, MLC1 and ClC-2 in astrocytes: implications in megalencephalic leukoencephalopathy.Disrupting MLC1 and GlialCAM and ClC-2 interactions in leukodystrophy entails glial chloride channel dysfunction.Seizures and disturbed brain potassium dynamics in the leukodystrophy megalencephalic leukoencephalopathy with subcortical cysts.Megalencephalic leukoencephalopathy with subcortical cysts: Characterization of disease variants.
P2860
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P2860
Insights into MLC pathogenesis: GlialCAM is an MLC1 chaperone required for proper activation of volume-regulated anion currents.
description
2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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name
Insights into MLC pathogenesis ...... lume-regulated anion currents.
@en
Insights into MLC pathogenesis ...... lume-regulated anion currents.
@nl
type
label
Insights into MLC pathogenesis ...... lume-regulated anion currents.
@en
Insights into MLC pathogenesis ...... lume-regulated anion currents.
@nl
prefLabel
Insights into MLC pathogenesis ...... lume-regulated anion currents.
@en
Insights into MLC pathogenesis ...... lume-regulated anion currents.
@nl
P2093
P2860
P50
P356
P1476
Insights into MLC pathogenesis ...... olume-regulated anion currents
@en
P2093
Gerard Callejo
Sònia Sirisi
Tania López-Hernández
Tanit Arnedo
Virginia Nunes
Xavier Capdevila-Nortes
P2860
P304
P356
10.1093/HMG/DDT290
P577
2013-06-20T00:00:00Z