Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial. - Wikidata - awgldk - TriplyDB

Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial.

Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial.

http://www.wikidata.org/entity/Q44121424

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Statins for the treatment of dementia Statins for the treatment of dementia Statin adverse effects : a review of the literature and evidence for a mitochondrial mechanism Simvastatin is associated with a reduced incidence of dementia and Parkinson's disease The "Statinth" wonder of the world: a panacea for all illnesses or a bubble about to burst.Targeting innate immunity for neurodegenerative disorders of the central nervous system Do statins impair cognition? A systematic review and meta-analysis of randomized controlled trials Neuroinflammation in Alzheimer's disease ApoAI deficiency results in marked reductions in plasma cholesterol but no alterations in amyloid-beta pathology in a mouse model of Alzheimer's disease-like cerebral amyloidosis Dose-specific effect of simvastatin on hypoxia-induced HIF-1α and BACE expression in Alzheimer's disease cybrid cells.Possible modification of Alzheimer's disease by statins in midlife: interactions with genetic and non-genetic risk factors The role of biomarkers in clinical trials for Alzheimer disease Changing concepts of cerebrospinal fluid hydrodynamics: role of phase-contrast magnetic resonance imaging and implications for cerebral microvascular disease.Cholesterol-modifying strategies for Alzheimer's disease.Simvastatin enhances hippocampal long-term potentiation in C57BL/6 mice.Neuroinflammatory challenges compromise neuronal function in the aging brain: Postoperative cognitive delirium and Alzheimer's disease.Toward onset prevention of cognitive decline in adults with Down syndrome (the TOP-COG study): study protocol for a randomized controlled trial.Secretory phospholipase A2 type III enhances alpha-secretase-dependent amyloid precursor protein processing through alterations in membrane fluidity.Association of statin use with cognitive decline in elderly African Americans.Geranylgeranyl pyrophosphate stimulates gamma-secretase to increase the generation of Abeta and APP-CTFgamma.Journal Club: a randomized, double-blind, placebo-controlled trial of simvastatin to treat Alzheimer disease.Statin-associated memory loss: analysis of 60 case reports and review of the literature.Simvastatin treatment enhances NMDAR-mediated synaptic transmission by upregulating the surface distribution of the GluN2B subunit.Cochrane review on 'Statins for the treatment of dementia'.Current and emerging drug treatment options for Alzheimer's disease: a systematic review.Therapy for Alzheimer's Disease: How Effective are Current Treatments?Treatment of vascular risk factors in patients with a diagnosis of Alzheimer's disease: a systematic review.Gamma-secretase-dependent amyloid-beta is increased in Niemann-Pick type C: a cross-sectional study Long-term high-dose atorvastatin decreases brain oxidative and nitrosative stress in a preclinical model of Alzheimer disease: a novel mechanism of action.Prevention and treatment of dementia or Alzheimer's disease by statins: a meta-analysis.Prevention of Alzheimer disease. Encouraging evidence.Molecular mechanisms underlying the effects of statins in the central nervous system.Systematic review of atorvastatin for the treatment of Alzheimer's disease High dietary cholesterol facilitates classical conditioning of the rabbit's nictitating membrane response.Cholesterol-independent neuroprotective and neurotoxic activities of statins: perspectives for statin use in Alzheimer disease and other age-related neurodegenerative disorders 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors in the treatment of central nervous system diseases.The microglial NADPH oxidase complex as a source of oxidative stress in Alzheimer's disease A randomized, double-blind, placebo-controlled trial of simvastatin to treat Alzheimer disease.Clinically tested drugs for Alzheimer's disease.Age-varying association between statin use and incident Alzheimer's disease.

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Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial.

http://www.wikidata.org/entity/Q44121424

description

2002 nî lūn-bûn

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Annals of Neurology

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Dieter Lütjohann

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Frank Schwärzler

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Henning Wormstall

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346-350

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10.1002/ANA.10292

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3

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Konrad Beyreuther

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2002-09-01T00:00:00Z

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12205648

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