Th2 activities induced during virgin T cell priming in the absence of IL-4, IL-13, and B cells.
about
Regulation of germinal center B-cell differentiationThe differential expression of IL-4 and IL-13 and its impact on type-2 immunitymicroRNA-155 regulates the generation of immunoglobulin class-switched plasma cellsHelios is associated with CD4 T cells differentiating to T helper 2 and follicular helper T cells in vivo independently of Foxp3 expression.Extrafollicular antibody responses.T-cell subsets in the germinal center.Natural and vaccine-mediated immunity to Salmonella Typhimurium is impaired by the helminth Nippostrongylus brasiliensis.CD31 is required on CD4+ T cells to promote T cell survival during Salmonella infectionType 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic non-eosinophil cells of the innate immune system.ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity.The porin OmpD from nontyphoidal Salmonella is a key target for a protective B1b cell antibody responseThe mechanisms of action of vaccines containing aluminum adjuvants: an in vitro vs in vivo paradigm.Cutting edge: basophils are transiently recruited into the draining lymph nodes during helminth infection via IL-3, but infection-induced Th2 immunity can develop without basophil lymph node recruitment or IL-3.IL-4 directs both CD4 and CD8 T cells to produce Th2 cytokines in vitro, but only CD4 T cells produce these cytokines in response to alum-precipitated protein in vivo.Cognate interactions: extrafollicular IL-4 drives germinal-center reactions, a new role for an old cytokine.Loss of CD154 impairs the Th2 extrafollicular plasma cell response but not early T cell proliferation and interleukin-4 induction.Pinpointing IL-4-independent acquisition and IL-4-influenced maintenance of Th2 activity by CD4 T cells.IgG1 Is Required for Optimal Protection after Immunization with the Purified Porin OmpD from Salmonella Typhimurium.Early simultaneous production of intranodal CD4 Th2 effectors and recirculating rapidly responding central-memory-like CD4 T cells.Soluble flagellin, FliC, induces an Ag-specific Th2 response, yet promotes T-bet-regulated Th1 clearance of Salmonella typhimurium infection.Responses to the soluble flagellar protein FliC are Th2, while those to FliC on Salmonella are Th1.Recirculating CD4 memory T cells mount rapid secondary responses without major contributions from follicular CD4 effectors and B cells.Type I cytokine profiles of human naïve and memory B lymphocytes: a potential for memory cells to impact polarization.Ligation of CD11c during vaccination promotes germinal centre induction and robust humoral responses without adjuvant.
P2860
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P2860
Th2 activities induced during virgin T cell priming in the absence of IL-4, IL-13, and B cells.
description
2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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2002年学术文章
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2002年学术文章
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name
Th2 activities induced during ...... e of IL-4, IL-13, and B cells.
@en
Th2 activities induced during ...... e of IL-4, IL-13, and B cells.
@nl
type
label
Th2 activities induced during ...... e of IL-4, IL-13, and B cells.
@en
Th2 activities induced during ...... e of IL-4, IL-13, and B cells.
@nl
prefLabel
Th2 activities induced during ...... e of IL-4, IL-13, and B cells.
@en
Th2 activities induced during ...... e of IL-4, IL-13, and B cells.
@nl
P2093
P1476
Th2 activities induced during ...... ce of IL-4, IL-13, and B cells
@en
P2093
Adam F Cunningham
Andrew N McKenzie
Hans Acha-Orbea
Ian C M MacLennan
Mahmood Khan
Sonia Vacheron
P304
P356
10.4049/JIMMUNOL.169.6.2900
P407
P577
2002-09-01T00:00:00Z