Frequent genetic alterations in EGFR- and HER2-driven pathways in breast cancer brain metastases.
about
PI3K pathway inhibitors for the treatment of brain metastases with a focus on HER2+ breast cancerBreast cancer brain metastases: biology and new clinical perspectivesThe molecular genomics of metastatic brain tumours.Using the MCF10A/MCF10CA1a Breast Cancer Progression Cell Line Model to Investigate the Effect of Active, Mutant Forms of EGFR in Breast Cancer Development and Treatment Using Gefitinib.Cell type of origin as well as genetic alterations contribute to breast cancer phenotypesCytogenomic profiling of breast cancer brain metastases reveals potential for repurposing targeted therapeutics.EGFR and HER2 signaling in breast cancer brain metastasis.Changing molecular profile of brain metastases compared with matched breast primary cancers and impact on clinical outcomesClinicopathological significance of PTEN and PI3K/AKT signal transduction pathway in non-small cell lung cancerPTEN mediates the cross talk between breast and glial cells in brain metastases leading to rapid disease progression.Biology, detection, and clinical implications of circulating tumor cells.Integrated genomic and transcriptomic analysis of human brain metastases identifies alterations of potential clinical significance.Mutation distributions and clinical correlations of PIK3CA gene mutations in breast cancer.Metabolic advantages and vulnerabilities in brain metastases.Breast cancer brain metastasis: molecular mechanisms and directions for treatment
P2860
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P2860
Frequent genetic alterations in EGFR- and HER2-driven pathways in breast cancer brain metastases.
description
2013 nî lūn-bûn
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name
Frequent genetic alterations i ...... reast cancer brain metastases.
@en
Frequent genetic alterations i ...... reast cancer brain metastases.
@nl
type
label
Frequent genetic alterations i ...... reast cancer brain metastases.
@en
Frequent genetic alterations i ...... reast cancer brain metastases.
@nl
prefLabel
Frequent genetic alterations i ...... reast cancer brain metastases.
@en
Frequent genetic alterations i ...... reast cancer brain metastases.
@nl
P2093
P50
P1476
Frequent genetic alterations i ...... reast cancer brain metastases.
@en
P2093
Ina Hohensee
Isabell Witzel
Katrin Lamszus
Klaus Pantel
Manfred Westphal
Sabine Riethdorf
Sönke Meyer-Staeckling
Volkmar Müller
P356
10.1016/J.AJPATH.2013.03.023
P407
P577
2013-05-09T00:00:00Z