Fibronectin fragments and blocking antibodies to alpha2beta1 and alpha5beta1 integrins stimulate mitogen-activated protein kinase signaling and increase collagenase 3 (matrix metalloproteinase 13) production by human articular chondrocytes.
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Prolactin-induced protein mediates cell invasion and regulates integrin signaling in estrogen receptor-negative breast cancerOctacalcium phosphate crystals directly stimulate expression of inducible nitric oxide synthase through p38 and JNK mitogen-activated protein kinases in articular chondrocytes.Pathophysiology of osteoarthritis: canonical NF-κB/IKKβ-dependent and kinase-independent effects of IKKα in cartilage degradation and chondrocyte differentiationAlcohol stimulates activation of Snail, epidermal growth factor receptor signaling, and biomarkers of epithelial-mesenchymal transition in colon and breast cancer cellsAlpha 5 Integrin Mediates Osteoarthritic Changes in Mouse Knee JointsFibronectin fragment activation of proline-rich tyrosine kinase PYK2 mediates integrin signals regulating collagenase-3 expression by human chondrocytes through a protein kinase C-dependent pathwayIdentification of a gene regulatory network associated with prion replication.Integrin-dependent neutrophil migration in the injured mouse cornea.Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes.Alphav and beta1 integrins regulate dynamic compression-induced proteoglycan synthesis in 3D gel culture by distinct complementary pathwaysSynoviocyte-derived angiopoietin-like protein 2 contributes to synovial chronic inflammation in rheumatoid arthritisInhibitory effects of insulin-like growth factor-1 and osteogenic protein-1 on fibronectin fragment- and interleukin-1beta-stimulated matrix metalloproteinase-13 expression in human chondrocytes.NF-kappa B mediates the stimulation of cytokine and chemokine expression by human articular chondrocytes in response to fibronectin fragmentsp38gamma mitogen-activated protein kinase suppresses chondrocyte production of MMP-13 in response to catabolic stimulationIncreased matrix metalloproteinase-13 production with aging by human articular chondrocytes in response to catabolic stimuli.Use of cartilage derived from murine induced pluripotent stem cells for osteoarthritis drug screening.Endogenous production of reactive oxygen species is required for stimulation of human articular chondrocyte matrix metalloproteinase production by fibronectin fragmentsA New Application of Parallel Synthesis Strategy for Discovery of Amide-Linked Small Molecules as Potent Chondroprotective Agents in TNF-α-Stimulated Chondrocytes.The Interaction of CD154 with the α5β1 Integrin Inhibits Fas-Induced T Cell DeathLessons from genetic forms of osteoarthritis for the pathogenesis of the diseaseFibronectin fragment-induced expression of matrix metalloproteinases is mediated by MyD88-dependent TLR-2 signaling pathway in human chondrocytes.Regulation of alpha5beta1 integrin conformation and function by urokinase receptor binding.Comparison of marker gene expression in chondrocytes from patients receiving autologous chondrocyte transplantation versus osteoarthritis patientsIntegrins and chondrocyte-matrix interactions in articular cartilageCartilage destruction by matrix degradation productsInflammation and ischemia: macrophages activated by fibronectin fragments enhance the survival of injured cardiac myocytesHuman articular chondrocytes produce IL-7 and respond to IL-7 with increased production of matrix metalloproteinase-13.Cysteine-Mediated Redox Regulation of Cell Signaling in Chondrocytes Stimulated With Fibronectin Fragments.Rac1 is required for matrix metalloproteinase 13 production by chondrocytes in response to fibronectin fragmentsInterleukin-7 stimulates secretion of S100A4 by activating the JAK/STAT signaling pathway in human articular chondrocytesMitogen-activated protein kinases as therapeutic targets in osteoarthritis.Basic science of osteoarthritis.Immunomodulatory and anti-inflammatory effects of chondroitin sulphate.Beta1 integrin deficiency results in multiple abnormalities of the knee joint.MicroRNA-9 regulates survival of chondroblasts and cartilage integrity by targeting protogenin.Analysing the role of endogenous matrix molecules in the development of osteoarthritis.α5β1 integrin induces the expression of noncartilaginous procollagen gene expression in articular chondrocytes cultured in monolayers.Low oxygen tension increased fibronectin fragment induced catabolic activities--response prevented with biomechanical signalsBiology and pathology of Rho GTPase, PI-3 kinase-Akt, and MAP kinase signaling pathways in chondrocytes.Syndecans in cartilage breakdown and synovial inflammation.
P2860
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P2860
Fibronectin fragments and blocking antibodies to alpha2beta1 and alpha5beta1 integrins stimulate mitogen-activated protein kinase signaling and increase collagenase 3 (matrix metalloproteinase 13) production by human articular chondrocytes.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Fibronectin fragments and bloc ...... human articular chondrocytes.
@en
Fibronectin fragments and bloc ...... ing and increase collagenase 3
@nl
type
label
Fibronectin fragments and bloc ...... human articular chondrocytes.
@en
Fibronectin fragments and bloc ...... ing and increase collagenase 3
@nl
prefLabel
Fibronectin fragments and bloc ...... human articular chondrocytes.
@en
Fibronectin fragments and bloc ...... ing and increase collagenase 3
@nl
P2093
P2860
P356
P1476
Fibronectin fragments and bloc ...... human articular chondrocytes.
@en
P2093
Christopher B Forsyth
Judit Pulai
Richard F Loeser
P2860
P304
P356
10.1002/ART.10502
P577
2002-09-01T00:00:00Z