A3 adenosine receptor knockout mice are protected against ischemia- and myoglobinuria-induced renal failure. - Wikidata - awgldk - TriplyDB

A3 adenosine receptor knockout mice are protected against ischemia- and myoglobinuria-induced renal failure.

A3 adenosine receptor knockout mice are protected against ischemia- and myoglobinuria-induced renal failure.

http://www.wikidata.org/entity/Q44185781

about

Adenosine receptors as therapeutic targets Purinergic signalling in the kidney in health and disease Role of the adenosine(2A) receptor-epoxyeicosatrienoic acid pathway in the development of salt-sensitive hypertension Adenosine receptors and the kidney Adenosine A3 receptor activation attenuates lung ischemia-reperfusion injury.Targeting of adenosine receptors in ischemia-reperfusion injury.Structural determinants of efficacy at A3 adenosine receptors: modification of the ribose moiety.Immune mechanisms and novel pharmacological therapies of acute kidney injury.Cytoprotective effects of adenosine and inosine in an in vitro model of acute tubular necrosis.Adenosine A(3) receptors regulate heart rate, motor activity and body temperature.A3 and P2Y2 receptors control the recruitment of neutrophils to the lungs in a mouse model of sepsis Adenosine receptors and renal ischaemia reperfusion injury.Adenosine, lidocaine and Mg2+ improves cardiac and pulmonary function, induces reversible hypotension and exerts anti-inflammatory effects in an endotoxemic porcine model.A3 adenosine receptors and mitogen-activated protein kinases in lung injury following in vivo reperfusion.Adenosine A(2A) receptors play a role in the pathogenesis of hepatic cirrhosis Enhanced neurodegeneration after a high dose of methamphetamine in adenosine A3 receptor null mutant mice Adenosine and protection from acute kidney injury.A1 adenosine receptor allosteric enhancer PD-81723 protects against renal ischemia-reperfusion injury Intestinal ischemia-reperfusion injury alters purinergic receptor expression in clinically relevant extraintestinal organs.Investigational A₃ adenosine receptor targeting agents.Sevoflurane protects against renal ischemia and reperfusion injury in mice via the transforming growth factor-beta1 pathway Adora2b adenosine receptor signaling protects during acute kidney injury via inhibition of neutrophil-dependent TNF-α release Renoprotective Effects of a Highly Selective A3 Adenosine Receptor Antagonist in a Mouse Model of Adriamycin-induced Nephropathy Genetic Abrogation of Adenosine A3 Receptor Prevents Uninephrectomy and High Salt-Induced Hypertension.Synthesis and anti-renal fibrosis activity of conformationally locked truncated 2-hexynyl-N(6)-substituted-(N)-methanocarba-nucleosides as A3 adenosine receptor antagonists and partial agonists.Novel aspects of pharmacological therapies for acute renal failure.The A3 adenosine receptor as multifaceted therapeutic target: pharmacology, medicinal chemistry, and in silico approaches.The CD39-adenosinergic axis in the pathogenesis of renal ischemia-reperfusion injury.Region-specific alterations of adenosine receptors expression level in kidney of diabetic rat.Adenosine produced from adenine nucleotides through an interaction between apoptotic cells and engulfing macrophages contributes to the appearance of transglutaminase 2 in dying thymocytes.Activation of A3 adenosine receptor provides lung protection against ischemia-reperfusion injury associated with reduction in apoptosis.A(1) and A(3) adenosine receptors alter glutathione status in an organ-specific manner and influence the changes after inhibition of gamma-glutamylcysteine ligase.Short- and long-term A3 adenosine receptor activation inhibits the Na+/H+ exchanger NHE3 activity and expression in opossum kidney cells.Renal interstitial adenosine is increased in angiotensin II-induced hypertensive rats.Isoflurane protects against renal ischemia and reperfusion injury and modulates leukocyte infiltration in mice.Orally active, species-independent novel A3 adenosine receptor antagonist protects against kidney injury in db/db mice.

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P2860

A3 adenosine receptor knockout mice are protected against ischemia- and myoglobinuria-induced renal failure.

http://www.wikidata.org/entity/Q44185781

description

2002 nî lūn-bûn

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2002年の論文

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年學術文章

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2002年學術文章

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name

A3 adenosine receptor knockout ...... binuria-induced renal failure.

@en

A3 adenosine receptor knockout ...... binuria-induced renal failure.

@nl

type

label

A3 adenosine receptor knockout ...... binuria-induced renal failure.

@en

A3 adenosine receptor knockout ...... binuria-induced renal failure.

@nl

prefLabel

A3 adenosine receptor knockout ...... binuria-induced renal failure.

@en

A3 adenosine receptor knockout ...... binuria-induced renal failure.

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AJPRENAL.00271.2002

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American Journal of Physiology - Renal Physiology

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A3 adenosine receptor knockout ...... binuria-induced renal failure.

@en

P2093

Ayuko Ota-Setlik

http://www.w3.org/2001/XMLSchema#string

Charles W Emala

http://www.w3.org/2001/XMLSchema#string

H Thomas Lee

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Hua Xu

http://www.w3.org/2001/XMLSchema#string

Marlene A Jacobson

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Vivette D D'Agati

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P2860

Pharmacological characterization of adenosine receptors in PGT-beta mouse pineal gland tumour cells

Targeted deletion of the A3 adenosine receptor confers resistance to myocardial ischemic injury and does not prevent early preconditioning

Pharmacological characterization of novel A3 adenosine receptor-selective antagonists

Disruption of the A(3) adenosine receptor gene in mice and its effect on stimulated inflammatory cells

Targeted deletion of A(3) adenosine receptors improves tolerance to ischemia-reperfusion injury in mouse myocardium.

Nucleoside-induced arteriolar constriction: a mast cell-dependent response.

Adenosine receptor ligands: potential as therapeutic agents in asthma and COPD.

Adenosine A3 receptors: novel ligands and paradoxical effects.

Adenosine and inosine increase cutaneous vasopermeability by activating A(3) receptors on mast cells

Induction of apoptosis in cardiac myocytes by an A3 adenosine receptor agonist.

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