Identification and characterization of the single channel function of human mucolipin-1 implicated in mucolipidosis type IV, a disorder affecting the lysosomal pathway.
about
A model of lysosomal pH regulationClarifying lysosomal storage diseasesNeurologic, gastric, and opthalmologic pathologies in a murine model of mucolipidosis type IVTRP channel Ca(2+) sparklets: fundamental signals underlying endothelium-dependent hyperpolarizationThe role of TRPMLs in endolysosomal trafficking and functionPermeation, regulation and control of expression of TRP channels by trace metal ionsMucolipidosis type IV: an updateRegulation of calcium signaling by polycystin-2Identification and analysis of cation channel homologues in human pathogenic fungiSystematic screens for proteins that interact with the mucolipidosis type IV protein TRPML1Accumulation of glycosphingolipids in Niemann-Pick C disease disrupts endosomal transportMacroautophagy is defective in mucolipin-1-deficient mouse neuronsReconstitution and characterization of a nicotinic acid adenine dinucleotide phosphate (NAADP)-sensitive Ca2+ release channel from liver lysosomes of ratsTRP channelsPlasticity of mouse renal collecting duct in response to potassium depletion.Lysosomal trafficking functions of mucolipin-1 in murine macrophagesRoles of CUP-5, the Caenorhabditis elegans orthologue of human TRPML1, in lysosome and gut granule biogenesis.Aberrant Ca2+ handling in lysosomal storage disordersMucolipins: Intracellular TRPML1-3 channelsTRP channels of intracellular membranesTwo-pore channels: Regulation by NAADP and customized roles in triggering calcium signalsThe calcium channel mucolipin-3 is a novel regulator of trafficking along the endosomal pathwayThe TRP superfamily of cation channels.TRP-ML1 is a lysosomal monovalent cation channel that undergoes proteolytic cleavage.Two di-leucine motifs regulate trafficking of mucolipin-1 to lysosomesThe cation channel mucolipin-1 is a bifunctional protein that facilitates membrane remodeling via its serine lipase domain.Up-regulation of lysosomal TRPML1 channels is essential for lysosomal adaptation to nutrient starvation.Regulation of TRPML1 function.The cell biology of lysosomal storage disorders.Loss of lysosomal ion channel transient receptor potential channel mucolipin-1 (TRPML1) leads to cathepsin B-dependent apoptosis.Role of protein kinase d in Golgi exit and lysosomal targeting of the transmembrane protein, Mcoln1.Hair-Cell Mechanotransduction Persists in TRP Channel Knockout Mice.TRP channels in disease.Acidic Ca2+ stores in neurodegeneration.TRPpathies.ESCRT-Dependent Cell Death in a Caenorhabditis elegans Model of the Lysosomal Storage Disorder Mucolipidosis Type IV.Membrane traffic and turnover in TRP-ML1-deficient cells: a revised model for mucolipidosis type IV pathogenesisAutophagic dysfunction in mucolipidosis type IV patients.TRP-ML1 functions as a lysosomal NAADP-sensitive Ca2+ release channel in coronary arterial myocytesGlycosphingolipid storage leads to the enhanced degradation of the B cell receptor in Sandhoff disease mice.
P2860
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P2860
Identification and characterization of the single channel function of human mucolipin-1 implicated in mucolipidosis type IV, a disorder affecting the lysosomal pathway.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Identification and characteriz ...... fecting the lysosomal pathway.
@en
Identification and characteriz ...... fecting the lysosomal pathway.
@nl
type
label
Identification and characteriz ...... fecting the lysosomal pathway.
@en
Identification and characteriz ...... fecting the lysosomal pathway.
@nl
prefLabel
Identification and characteriz ...... fecting the lysosomal pathway.
@en
Identification and characteriz ...... fecting the lysosomal pathway.
@nl
P2093
P2860
P1433
P1476
Identification and characteriz ...... fecting the lysosomal pathway.
@en
P2093
Edward M Brown
Janice M LaPlante
John Falardeau
Marie Kanazirska
Peter M Vassilev
Susan A Slaugenhaupt
P2860
P304
P356
10.1016/S0014-5793(02)03670-0
P407
P577
2002-12-01T00:00:00Z