Inactivation of homologous recombination suppresses defects in topoisomerase III-deficient mutants.
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BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediatesMus81 functions in the quality control of replication forks at the rDNA and is involved in the maintenance of rDNA repeat number in Saccharomyces cerevisiaeEvidence that the S.cerevisiae Sgs1 protein facilitates recombinational repair of telomeres during senescence.Structure and function of the regulatory HRDC domain from human Bloom syndrome proteinMutations in homologous recombination genes rescue top3 slow growth in Saccharomyces cerevisiae.Yeast Rmi1/Nce4 controls genome stability as a subunit of the Sgs1-Top3 complex.RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complexInfertility and aneuploidy in mice lacking a type IA DNA topoisomerase III betaTOPO3alpha influences antigenic variation by monitoring expression-site-associated VSG switching in Trypanosoma brucei.The HRDC domain of BLM is required for the dissolution of double Holliday junctionsThe dissolution of double Holliday junctions.Alternate pathways involving Sgs1/Top3, Mus81/ Mms4, and Srs2 prevent formation of toxic recombination intermediates from single-stranded gaps created by DNA replication.Top3-Rmi1 DNA single-strand decatenase is integral to the formation and resolution of meiotic recombination intermediates.DNA topoisomerase III localizes to centromeres and affects centromeric CENP-A levels in fission yeast.The absence of Top3 reveals an interaction between the Sgs1 and Pif1 DNA helicases in Saccharomyces cerevisiae.Schizosaccharomyces pombe checkpoint response to DNA interstrand cross-linksDevelopment of autoimmunity in mice lacking DNA topoisomerase 3betaRecql5 plays an important role in DNA replication and cell survival after camptothecin treatment.Smc5/6 complex regulates Sgs1 recombination functions.Pervasive and essential roles of the Top3-Rmi1 decatenase orchestrate recombination and facilitate chromosome segregation in meiosis.Top3 processes recombination intermediates and modulates checkpoint activity after DNA damage.Resolution of converging replication forks by RecQ and topoisomerase III.Shu proteins promote the formation of homologous recombination intermediates that are processed by Sgs1-Rmi1-Top3.Sgs1 regulates gene conversion tract lengths and crossovers independently of its helicase activity.Sgs1's roles in DNA end resection, HJ dissolution, and crossover suppression require a two-step SUMO regulation dependent on Smc5/6.Pathways for Holliday junction processing during homologous recombination in Saccharomyces cerevisiae.Roles of SGS1, MUS81, and RAD51 in the repair of lagging-strand replication defects in Saccharomyces cerevisiae.Role of Blm and collaborating factors in recombination and survival following replication stress in Ustilago maydis.The genetic consequences of ablating helicase activity and the Top3 interaction domain of Sgs1.Multi-invasions Are Recombination Byproducts that Induce Chromosomal Rearrangements.Viability of Escherichia coli topA mutants lacking DNA topoisomerase I.
P2860
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P2860
Inactivation of homologous recombination suppresses defects in topoisomerase III-deficient mutants.
description
2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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2002年学术文章
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2002年学术文章
@zh-hans
2002年学术文章
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2002年学术文章
@zh-sg
2002年學術文章
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2002年學術文章
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2002年學術文章
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name
Inactivation of homologous rec ...... omerase III-deficient mutants.
@en
Inactivation of homologous rec ...... omerase III-deficient mutants.
@nl
type
label
Inactivation of homologous rec ...... omerase III-deficient mutants.
@en
Inactivation of homologous rec ...... omerase III-deficient mutants.
@nl
prefLabel
Inactivation of homologous rec ...... omerase III-deficient mutants.
@en
Inactivation of homologous rec ...... omerase III-deficient mutants.
@nl
P2093
P1433
P1476
Inactivation of homologous rec ...... omerase III-deficient mutants.
@en
P2093
Adele Goodwin
Ian D Hickson
Thomas J Oakley
P304
P356
10.1016/S1568-7864(02)00032-0
P577
2002-06-01T00:00:00Z