Squalene synthase inhibitors suppress triglyceride biosynthesis through the farnesol pathway in rat hepatocytes.
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Increased cholesterol biosynthesis and hypercholesterolemia in mice overexpressing squalene synthase in the liverA novel bisphosphonate inhibitor of squalene synthase combined with a statin or a nitrogenous bisphosphonate in vitroPlasma cholesterol-lowering and transient liver dysfunction in mice lacking squalene synthase in the liverThe glucagon receptor is required for the adaptive metabolic response to fastingGenome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease.Soymorphin-5, a soy-derived μ-opioid peptide, decreases glucose and triglyceride levels through activating adiponectin and PPARα systems in diabetic KKAy mice.Recent developments in the treatment of atherosclerosis.Nonsterol Isoprenoids Activate Human Constitutive Androstane Receptor in an Isoform-Selective Manner in Primary Cultured Mouse Hepatocytes.Cholesterol and chronic hepatitis C virus infection.Regulation of fatty acid synthesis by farnesyl pyrophosphate.Lapaquistat acetate, a squalene synthase inhibitor, changes macrophage/lipid-rich coronary plaques of hypercholesterolaemic rabbits into fibrous lesions.Differential Regulation of Gene Expression by Cholesterol Biosynthesis Inhibitors That Reduce (Pravastatin) or Enhance (Squalestatin 1) Nonsterol Isoprenoid Levels in Primary Cultured Mouse and Rat HepatocytesIn vitro activities of ER-119884 and E5700, two potent squalene synthase inhibitors, against Leishmania amazonensis: antiproliferative, biochemical, and ultrastructural effects.Synthetic arylquinuclidine derivatives exhibit antifungal activity against Candida albicans, Candida tropicalis and Candida parapsilopsis.Farnesol, an isoprenoid, improves metabolic abnormalities in mice via both PPARα-dependent and -independent pathways.
P2860
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P2860
Squalene synthase inhibitors suppress triglyceride biosynthesis through the farnesol pathway in rat hepatocytes.
description
2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年學術文章
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name
Squalene synthase inhibitors s ...... ol pathway in rat hepatocytes.
@en
Squalene synthase inhibitors s ...... ol pathway in rat hepatocytes.
@nl
type
label
Squalene synthase inhibitors s ...... ol pathway in rat hepatocytes.
@en
Squalene synthase inhibitors s ...... ol pathway in rat hepatocytes.
@nl
prefLabel
Squalene synthase inhibitors s ...... ol pathway in rat hepatocytes.
@en
Squalene synthase inhibitors s ...... ol pathway in rat hepatocytes.
@nl
P2093
P2860
P1476
Squalene synthase inhibitors s ...... ol pathway in rat hepatocytes.
@en
P2093
Daisuke Shinmyo
Hironobu Hiyoshi
Hironori Ikuta
Hiroshi Tanaka
Ichiro Yoshida
Keigo Tanaka
Mamoru Yanagimachi
Masashi Ito
Nobuyuki Kurusu
Nobuyuki Yasuda
P2860
P304
P356
10.1194/JLR.M200316-JLR200
P577
2003-01-01T00:00:00Z