Interaction of human NAD(P)H:quinone oxidoreductase 1 (NQO1) with the tumor suppressor protein p53 in cells and cell-free systems.
about
Implications of NQO1 in cancer therapyQuercetin as an Emerging Anti-Melanoma Agent: A Four-Focus Area Therapeutic Development StrategyNAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotectorA mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73Influence of cell cycle on responses of MCF-7 cells to benzo[a]pyreneImpairment of antioxidant defenses as a contributor to arsenite-induced cell transformationTime- and concentration-dependent changes in gene expression induced by benzo(a)pyrene in two human cell lines, MCF-7 and HepG2.ATBF1 and NQO1 as candidate targets for allelic loss at chromosome arm 16q in breast cancer: absence of somatic ATBF1 mutations and no role for the C609T NQO1 polymorphismIn vitro gene regulatory networks predict in vivo function of liverRelationships between metabolic and non-metabolic susceptibility factors in benzene toxicity.K12-biotinylated histone H4 is enriched in telomeric repeats from human lung IMR-90 fibroblasts.Inhibition of NAD(P)H:quinone oxidoreductase 1 activity and induction of p53 degradation by the natural phenolic compound curcumin.NAD(P)H:quinone oxidoreductase 1 is induced by progesterone in cardiomyocytes.Inactivation of the quinone oxidoreductases NQO1 and NQO2 strongly elevates the incidence and multiplicity of chemically induced skin tumors.P53 hot-spot mutants are resistant to ubiquitin-independent degradation by increased binding to NAD(P)H:quinone oxidoreductase 1Ubiquitin proteasomal pathway mediated degradation of p53 in melanomaPrognostic significance of NQO1 expression in intrahepatic cholangiocarcinoma.Calorie restriction up-regulates the plasma membrane redox system in brain cells and suppresses oxidative stress during agingRole of gene knockout and transgenic mice in the study of xenobiotic metabolism.A direct interaction between NQO1 and a chemotherapeutic dimeric naphthoquinone.Quinone reductases multitasking in the metabolic world.Excess transmission of the NAD(P)H:quinone oxidoreductase 1 (NQO1) C609T polymorphism in families of children with acute lymphoblastic leukemia.Osteopontin is an endogenous modulator of the constitutively activated phenotype of pulmonary adventitial fibroblasts in hypoxic pulmonary hypertension.Versatile functions of p53 protein in multicellular organismsArtemis is a negative regulator of p53 in response to oxidative stressActivation of NQO1 in NQO1*2 polymorphic human leukemic HL-60 cells by diet-derived sulforaphaneRedox modulation of p53: mechanisms and functional significance.NAD(P)H: quinone oxidoreductase 1 and its potential protective role in cardiovascular diseases and related conditions.Using DNA devices to track anticancer drug activity.DNA damage signalling barrier, oxidative stress and treatment-relevant DNA repair factor alterations during progression of human prostate cancer.NQO1 suppresses NF-κB-p300 interaction to regulate inflammatory mediators associated with prostate tumorigenesis.Genetic polymorphisms of NQO1, CYP1A1 and TPMT and susceptibility to acute lymphoblastic leukemia in a Tunisian population.Up-regulation of plasma membrane-associated redox activities in neuronal cells lacking functional mitochondria.Can dicoumarol be used as a gonad-safe anticancer agent: an in vitro and in vivo experimental study.The two common polymorphic forms of human NRH-quinone oxidoreductase 2 (NQO2) have different biochemical properties.Site-to-site interdomain communication may mediate different loss-of-function mechanisms in a cancer-associated NQO1 polymorphism.Benzene toxicity: The role of the susceptibility factor NQO1 in bone marrow endothelial cell signaling and function.Clonal haemopoiesis may occur after conventional chemotherapy and is associated with accelerated telomere shortening and defects in the NQO1 pathway; possible mechanisms leading to an increased risk of t-AML/MDS.Genetic polymorphism of NAD(P)H:quinone oxidoreductase is associated with an increased risk of infant acute lymphoblastic leukemia without MLL gene rearrangements.NAD(P)H:quinone oxidoreductase 1 NQO1*2 genotype (P187S) is a strong prognostic and predictive factor in breast cancer.
P2860
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P2860
Interaction of human NAD(P)H:quinone oxidoreductase 1 (NQO1) with the tumor suppressor protein p53 in cells and cell-free systems.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Interaction of human NAD
@nl
Interaction of human NAD(P)H:q ...... n cells and cell-free systems.
@en
type
label
Interaction of human NAD
@nl
Interaction of human NAD(P)H:q ...... n cells and cell-free systems.
@en
prefLabel
Interaction of human NAD
@nl
Interaction of human NAD(P)H:q ...... n cells and cell-free systems.
@en
P2093
P2860
P356
P1476
Interaction of human NAD(P)H:q ...... n cells and cell-free systems.
@en
P2093
Adil Anwar
David Ross
David Siegel
Donna Dehn
Jadwiga K Kepa
Luo Jia Tang
P2860
P304
10368-10373
P356
10.1074/JBC.M211981200
P407
P577
2003-01-14T00:00:00Z