E-Tmod capping of actin filaments at the slow-growing end is required to establish mouse embryonic circulation.
about
Leiomodin 1, a new serum response factor-dependent target gene expressed preferentially in differentiated smooth muscle cellsTropomodulin capping of actin filaments in striated muscle development and physiologyRestricted inactivation of serum response factor to the cardiovascular systemKnockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethalityDeficiency of Myo18B in mice results in embryonic lethality with cardiac myofibrillar aberrationsAberrant myofibril assembly in tropomodulin1 null mice leads to aborted heart development and embryonic lethalityTropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiologyTmod1 and CP49 synergize to control the fiber cell geometry, transparency, and mechanical stiffness of the mouse lensLmod2 piggyBac mutant mice exhibit dilated cardiomyopathy.Tropomodulin 1-null mice have a mild spherocytic elliptocytosis with appearance of tropomodulin 3 in red blood cells and disruption of the membrane skeletonThe minus-end actin capping protein, UNC-94/tropomodulin, regulates development of the Caenorhabditis elegans intestineNew components of the Drosophila fusome suggest it plays novel roles in signaling and transport.Tropomyosin is required for cardiac morphogenesis, myofibril assembly, and formation of adherens junctions in the developing mouse embryoPhosphorylation of tropomodulin1 contributes to the regulation of actin filament architecture in cardiac muscle.Erythrocyte tropomodulin isoforms with and without the N-terminal actin-binding domainDynamic regulation of sarcomeric actin filaments in striated muscleIdentification of residues within tropomodulin-1 responsible for its localization at the pointed ends of the actin filaments in cardiac myocytes.Leiomodin 3 and tropomodulin 4 have overlapping functions during skeletal myofibrillogenesis.Cytoplasmic gamma-actin and tropomodulin isoforms link to the sarcoplasmic reticulum in skeletal muscle fibers.Defective erythroid maturation in gelsolin mutant mice.Molecular basis of tropomyosin binding to tropomodulin, an actin-capping protein.The interaction of tropomodulin with tropomyosin stabilizes thin filaments in cardiac myocytes.Tropomodulins and tropomyosins: working as a teamRole of Active Contraction and Tropomodulins in Regulating Actin Filament Length and Sarcomere Structure in Developing Zebrafish Skeletal Muscle.Sarcomeric actin organization is synergistically promoted by tropomodulin, ADF/cofilin, AIP1 and profilin in C. elegansErythroid development in the mammalian embryo.The modern primitives: applying new technological approaches to explore the biology of the earliest red blood cellsDesigning heart performance by gene transfer.Tropomodulin1 is required in the heart but not the yolk sac for mouse embryonic development.Tropomodulin1 is required for membrane skeleton organization and hexagonal geometry of fiber cells in the mouse lens.Tropomodulins: pointed-end capping proteins that regulate actin filament architecture in diverse cell types.The cardiomyopathy-associated K15N mutation in tropomyosin alters actin filament pointed end dynamics.Tropomodulins and Leiomodins: Actin Pointed End Caps and Nucleators in Muscles.Actin in striated muscle: recent insights into assembly and maintenanceOverview of the Muscle Cytoskeleton.Leiomodin-2 is an antagonist of tropomodulin-1 at the pointed end of the thin filaments in cardiac muscle.Formation, contraction, and mechanotransduction of myofribrils in cardiac development: clues from genetics.Tropomodulin protects α-catenin-dependent junctional-actin networks under stress during epithelial morphogenesisThe influence of fluid shear stress on the remodeling of the embryonic primary capillary plexus.Characterizing interaction forces between actin and proteins of the tropomodulin family reveals the presence of the N-terminal actin-binding site in leiomodin.
P2860
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P2860
E-Tmod capping of actin filaments at the slow-growing end is required to establish mouse embryonic circulation.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
E-Tmod capping of actin filame ...... h mouse embryonic circulation.
@en
E-Tmod capping of actin filame ...... h mouse embryonic circulation.
@nl
type
label
E-Tmod capping of actin filame ...... h mouse embryonic circulation.
@en
E-Tmod capping of actin filame ...... h mouse embryonic circulation.
@nl
prefLabel
E-Tmod capping of actin filame ...... h mouse embryonic circulation.
@en
E-Tmod capping of actin filame ...... h mouse embryonic circulation.
@nl
P2093
P1476
E-Tmod capping of actin filame ...... h mouse embryonic circulation.
@en
P2093
Carlos Vera
K-L Paul Sung
Lanping Amy Sung
Mary C Reedy
P304
P356
10.1152/AJPHEART.00947.2002
P577
2003-01-23T00:00:00Z