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Synthesis of cortistatins A, J, K and L.Total synthesis of (±)-cortistatin J from furan.A hypervalent iodine-induced double annulation enables a concise synthesis of the pentacyclic core structure of the cortistatins.Synthetic studies toward (+)-cortistatin AConstructing molecular complexity and diversity: total synthesis of natural products of biological and medicinal importance.A concise synthesis of the cortistatin core.A novel α,β-unsaturated nitrone-aryne [3+2] cycloaddition and its application in the synthesis of the cortistatin core.Catalytic skeletal reorganization of enynes through electrophilic activation of alkynes: double cleavage of C-C double and triple bonds.Chemoselectivity: the mother of invention in total synthesis.Synthesis of the Cortistatin Pentacyclic Core by Alkoxide-Directed Metallacycle-Mediated Annulative Cross-Coupling.Cortistatin A is a high-affinity ligand of protein kinases ROCK, CDK8, and CDK11.Stereodivergent synthesis of 17-alpha and 17-beta-alpharyl steroids: application and biological evaluation of D-ring cortistatin analogues.Synthesis and anti-angiogenic activity of cortistatin analogs.Ga(III)-catalyzed cycloisomerization approach to (+/-)-icetexone and (+/-)-epi-icetexone.Formal total synthesis of (±)-cortistatin AScalable synthesis of cortistatin A and related structures.Improved synthesis of 8-oxabicyclo[3.2.1]octanes via tandem C-H oxidation/oxa-[3,3] Cope rearrangement/aldol cyclization.Vinylogous Nicholas reactions in the synthesis of bi- and tricyclic cycloheptynedicobalt complexes.A model study for the concise construction of the oxapentacyclic core of cortistatins through intramolecular Diels-Alder and oxidative dearomatization-cyclization reactions.
P2860
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P2860
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Rapid construction of the cortistatin pentacyclic core.
@en
Rapid construction of the cortistatin pentacyclic core.
@nl
type
label
Rapid construction of the cortistatin pentacyclic core.
@en
Rapid construction of the cortistatin pentacyclic core.
@nl
prefLabel
Rapid construction of the cortistatin pentacyclic core.
@en
Rapid construction of the cortistatin pentacyclic core.
@nl
P2093
P356
P1476
Rapid construction of the cortistatin pentacyclic core
@en
P2093
Alison R Hardin
Richmond Sarpong
Xuelei Guo
P304
P356
10.1002/ANIE.200802203
P407
P50
P577
2008-01-01T00:00:00Z