Development of an in vitro screen for compound bioaccumulation in Haemonchus contortus.

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Anthelmintic drug discovery: into the future.

P2860

Q38316710-AEB0A34E-B399-4D50-B293-0CAF0B56F14F

P2860

Development of an in vitro screen for compound bioaccumulation in Haemonchus contortus.

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http://www.wikidata.org/entity/Q44326814

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Development of an in vitro screen for compound bioaccumulation in Haemonchus contortus.

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Development of an in vitro screen for compound bioaccumulation in Haemonchus contortus.

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Item

label

Development of an in vitro screen for compound bioaccumulation in Haemonchus contortus.

@en

Development of an in vitro screen for compound bioaccumulation in Haemonchus contortus.

@nl

prefLabel

Development of an in vitro screen for compound bioaccumulation in Haemonchus contortus.

@en

Development of an in vitro screen for compound bioaccumulation in Haemonchus contortus.

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P1476

Development of an in vitro screen for compound bioaccumulation in Haemonchus contortus.

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P2093

Alan A Marchiondo

http://www.w3.org/2001/XMLSchema#string

Bernard D Hummel

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Christopher S Knauer

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David P Thompson

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Dawn A Merritt

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Debra J Woods

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Jinxia Nancy Deng

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Julie K Lorenz

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Matthew J Zaya

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Steven X Hu

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P2860

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Theoretical calculation and prediction of drug transport processes using simple parameters and partial least squares projections to latent structures (PLS) statistics. The use of electrotopological state indices.

Anthelmintics are substrates and activators of nematode P glycoprotein.

Analysis and comparison of 2D fingerprints: insights into database screening performance using eight fingerprint methods.

Molecular properties that influence the oral bioavailability of drug candidates.

Ivermectin resistance in nematodes may be caused by alteration of P-glycoprotein homolog.

The challenges of developing novel antiparasitic drugs.

Xenobiotic metabolizing enzymes and metabolism of anthelminthics in helminths.

Improving drug candidates by design: a focus on physicochemical properties as a means of improving compound disposition and safety.

Development of a new permeability assay using low-efflux MDCKII cells.

P304

848-855

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P31

scholarly article

P356

10.1645/14-556.1

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P433

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P478

100

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P577

2014-12-01T00:00:00Z

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P698

25116000

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Development of an in vitro screen for compound bioaccumulation in Haemonchus contortus.

about

P2860

P2860

Development of an in vitro screen for compound bioaccumulation in Haemonchus contortus.

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P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698