Chronic opioid use is associated with increased DNA methylation correlating with increased clinical pain.
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LINE-1 hypomethylation in spermatozoa is associated with Bisphenol A exposureEpigenetic regulation of persistent painMultigenerational and transgenerational inheritance of drug exposure: The effects of alcohol, opiates, cocaine, marijuana, and nicotineHigh-Throughput Analysis of Global DNA Methylation Using Methyl-Sensitive DigestionDisagreement between two common biomarkers of global DNA methylationPain vulnerability: a neurobiological perspective.DNA methylation at the mu-1 opioid receptor gene (OPRM1) promoter predicts preoperative, acute, and chronic postsurgical pain after spine fusion.Increased methylation of the MOR gene proximal promoter in primary sensory neurons plays a crucial role in the decreased analgesic effect of opioids in neuropathic pain.Epigenetic variation in the mu-opioid receptor gene in infants with neonatal abstinence syndromeEpigenetics across the human lifespan.Effects of methyl donor diets on incisional pain in mice.Epigenetics in the perioperative period.DNA Methylation Modulates Nociceptive Sensitization after Incision.Two-hit exposure to polychlorinated biphenyls at gestational and juvenile life stages: 2. Sex-specific neuromolecular effects in the brain.Overlapping signatures of chronic pain in the DNA methylation landscape of prefrontal cortex and peripheral T cellsMorphine paradoxically prolongs neuropathic pain in rats by amplifying spinal NLRP3 inflammasome activationThe role for epigenetic modifications in pain and analgesia response.A Framework to Examine the Role of Epigenetics in Health Disparities among Native AmericansTargeting Opioid-Induced Hyperalgesia in Clinical Treatment: Neurobiological Considerations.Pharmacoepigenomics of opiates and methadone maintenance treatment: current data and perspectives.Targeting Epigenetic Mechanisms for Chronic Pain: A Valid Approach for the Development of Novel Therapeutics.Drugging the pain epigenome.Transmission pathways and mediators as the basis for clinical pharmacology of pain.Correlation Between DNA Methylation of TRPA1 and Chronic Pain States in Human Whole Blood Cells.A computational functional genomics based self-limiting self-concentration mechanism of cell specialization as a biological role of jumping genes.DNMT3a methylation in neuropathic pain.Pharmacoepigenetics of the role of DNA methylation in μ-opioid receptor expression in different human brain regions.Elevated levels of DNA methylation at the OPRM1 promoter region in men with opioid use disorder.Chronic postsurgical pain: is there a possible genetic link?Transgenerational modification of hippocampus TNF-α and S100B levels in the offspring of rats chronically exposed to morphine during adolescence.Methadone induces hypermethylation of human DNA.Variability of response to methadone: genome-wide DNA methylation analysis in two independent cohorts.Psychosocial and demographic factors influencing pain scores of patients with knee osteoarthritis.Molecular Genetics and New Medication Strategies for Opioid AddictionWill Widespread Synthetic Opioid Consumption Induce Epigenetic Consequences in Future Generations?Plasma Concentration of Norepinephrine, β-endorphin, and Substance P in Lame Dairy CowsElevated methylation of OPRM1 and OPRL1 genes in Alzheimer's disease
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P2860
Chronic opioid use is associated with increased DNA methylation correlating with increased clinical pain.
description
2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
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2013年学术文章
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name
Chronic opioid use is associat ...... with increased clinical pain.
@en
Chronic opioid use is associat ...... with increased clinical pain.
@nl
type
label
Chronic opioid use is associat ...... with increased clinical pain.
@en
Chronic opioid use is associat ...... with increased clinical pain.
@nl
prefLabel
Chronic opioid use is associat ...... with increased clinical pain.
@en
Chronic opioid use is associat ...... with increased clinical pain.
@nl
P2093
P921
P1433
P1476
Chronic opioid use is associat ...... with increased clinical pain.
@en
P2093
Alexandra Doehring
Bruno Georg Oertel
Reinhard Sittl
P356
10.1016/J.PAIN.2012.06.011
P407
P50
P577
2013-01-01T00:00:00Z