Trypanosoma cruzi genome encodes a pteridine reductase 2 protein.
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Discovery of potent pteridine reductase inhibitors to guide antiparasite drug developmentPreclinical Evaluation of the Antifolate QN254, 5-Chloro- N'6'-(2,5-Dimethoxy-Benzyl)-Quinazoline-2,4,6-Triamine, as an Antimalarial Drug CandidateLipophilic antifolate trimetrexate is a potent inhibitor of Trypanosoma cruzi: prospect for chemotherapy of Chagas' disease.Crystallization and preliminary crystallographic studies of dihydrofolate reductase-thymidylate synthase from Trypanosoma cruzi, the Chagas disease pathogen.Inactivation of the Leishmania tarentolae pterin transporter (BT1) and reductase (PTR1) genes leads to viable parasites with changes in folate metabolism and hypersensitivity to the antifolate methotrexate.
P2860
Trypanosoma cruzi genome encodes a pteridine reductase 2 protein.
description
2003 nî lūn-bûn
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2003年の論文
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Trypanosoma cruzi genome encodes a pteridine reductase 2 protein.
@en
Trypanosoma cruzi genome encodes a pteridine reductase 2 protein.
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type
label
Trypanosoma cruzi genome encodes a pteridine reductase 2 protein.
@en
Trypanosoma cruzi genome encodes a pteridine reductase 2 protein.
@nl
prefLabel
Trypanosoma cruzi genome encodes a pteridine reductase 2 protein.
@en
Trypanosoma cruzi genome encodes a pteridine reductase 2 protein.
@nl
P2093
P1476
Trypanosoma cruzi genome encodes a pteridine reductase 2 protein.
@en
P2093
Biswajit Pal
Debasish Chattopadhyay
Norbert Schormann
Olga Senkovich
P356
10.1016/S0166-6851(02)00309-2
P577
2003-03-01T00:00:00Z