Agonist-induced signaling and trafficking of the mu-opioid receptor: role of serine and threonine residues in the third cytoplasmic loop and C-terminal domain.
about
Engineered G protein coupled receptors reveal independent regulation of internalization, desensitization and acute signalingNonselective coupling of the human mu-opioid receptor to multiple inhibitory G-protein isoformsAcute opioid receptor desensitization and tolerance: is there a link?Mutational analysis of the structure and function of opioid receptors.Confined diffusion without fences of a g-protein-coupled receptor as revealed by single particle tracking.Cellular signalling of non-synonymous single-nucleotide polymorphisms of the human μ-opioid receptor (OPRM1)Post-transcriptional regulation of opioid receptors in the nervous system.Chronic morphine treatment up-regulates mu opioid receptor binding in cells lacking filamin A.Role for G protein-coupled receptor kinase in agonist-specific regulation of mu-opioid receptor responsivenessSharpening the edges of understanding the structure/function of the LPA1 receptor: expression in cancer and mechanisms of regulation.Diffusion of the mu opioid receptor at the surface of human neuroblastoma SH-SY5Y cells is restricted to permeable domains.Effect of the A118G polymorphism on binding affinity, potency and agonist-mediated endocytosis, desensitization, and resensitization of the human mu-opioid receptor.Phosphorylation of Ser363, Thr370, and Ser375 residues within the carboxyl tail differentially regulates mu-opioid receptor internalization.Deltorphin II-induced rapid desensitization of delta-opioid receptor requires both phosphorylation and internalization of the receptor.The absence of a direct correlation between the loss of [D-Ala2, MePhe4,Gly5-ol]Enkephalin inhibition of adenylyl cyclase activity and agonist-induced mu-opioid receptor phosphorylation.Identification of serine 356 and serine 363 as the amino acids involved in etorphine-induced down-regulation of the mu-opioid receptor.Specific activation of the mu opioid receptor (MOR) by endomorphin 1 and endomorphin 2.Opioid agonists have different efficacy profiles for G protein activation, rapid desensitization, and endocytosis of mu-opioid receptors.U50,488H-induced internalization of the human kappa opioid receptor involves a beta-arrestin- and dynamin-dependent mechanism. Kappa receptor internalization is not required for mitogen-activated protein kinase activation.
P2860
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P2860
Agonist-induced signaling and trafficking of the mu-opioid receptor: role of serine and threonine residues in the third cytoplasmic loop and C-terminal domain.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh-hant
name
Agonist-induced signaling and ...... ic loop and C-terminal domain.
@en
Agonist-induced signaling and ...... ic loop and C-terminal domain.
@nl
type
label
Agonist-induced signaling and ...... ic loop and C-terminal domain.
@en
Agonist-induced signaling and ...... ic loop and C-terminal domain.
@nl
prefLabel
Agonist-induced signaling and ...... ic loop and C-terminal domain.
@en
Agonist-induced signaling and ...... ic loop and C-terminal domain.
@nl
P2093
P2860
P1433
P1476
Agonist-induced signaling and ...... mic loop and C-terminal domain
@en
P2093
P2860
P304
P356
10.1016/S0014-5793(97)01124-1
P407
P50
P577
1997-09-01T00:00:00Z