Novel 18F-Labeled κ-Opioid Receptor Antagonist as PET Radiotracer: Synthesis and In Vivo Evaluation of 18F-LY2459989 in Nonhuman Primates.

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Downregulation of the neuronal opioid gene expression concomitantly with neuronal decline in dorsolateral prefrontal cortex of human alcoholics.Anti-stress neuropharmacological mechanisms and targets for addiction treatment: A translational framework

P2860

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Novel 18F-Labeled κ-Opioid Receptor Antagonist as PET Radiotracer: Synthesis and In Vivo Evaluation of 18F-LY2459989 in Nonhuman Primates.

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http://www.wikidata.org/entity/Q44347602

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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name

Novel 18F-Labeled κ-Opioid Rec ...... Y2459989 in Nonhuman Primates.

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Novel 18F-Labeled κ-Opioid Rec ...... Y2459989 in Nonhuman Primates.

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type

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Novel 18F-Labeled κ-Opioid Rec ...... Y2459989 in Nonhuman Primates.

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Novel 18F-Labeled κ-Opioid Rec ...... Y2459989 in Nonhuman Primates.

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Novel 18F-Labeled κ-Opioid Rec ...... Y2459989 in Nonhuman Primates.

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Novel 18F-Labeled κ-Opioid Rec ...... Y2459989 in Nonhuman Primates.

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P1476

Novel 18F-Labeled κ-Opioid Rec ...... LY2459989 in Nonhuman Primates

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P2093

Antonio Navarro

http://www.w3.org/2001/XMLSchema#string

Daniel Holden

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David Labaree

http://www.w3.org/2001/XMLSchema#string

Jim Ropchan

http://www.w3.org/2001/XMLSchema#string

Michael Kapinos

http://www.w3.org/2001/XMLSchema#string

Ming-Qiang Zheng

http://www.w3.org/2001/XMLSchema#string

Shu-Fei Lin

http://www.w3.org/2001/XMLSchema#string

Songye Li

http://www.w3.org/2001/XMLSchema#string

Teresa Lara-Jaime

http://www.w3.org/2001/XMLSchema#string

Yiyun Huang

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P2860

Psychotomimesis mediated by kappa opiate receptors

A method to determine the ability of drugs to diffuse through the blood-brain barrier.

Evaluation of the agonist PET radioligand [¹¹C]GR103545 to image kappa opioid receptor in humans: kinetic model selection, test-retest reproducibility and receptor occupancy by the antagonist PF-04455242.

Identification of the first trans-(3R,4R)- dimethyl-4-(3-hydroxyphenyl)piperidine derivative to possess highly potent and selective opioid kappa receptor antagonist activity.

Discovery of aminobenzyloxyarylamides as κ opioid receptor selective antagonists: application to preclinical development of a κ opioid receptor antagonist receptor occupancy tracer.

Positron emission tomography compartmental models.

An Improved Antagonist Radiotracer for the κ-Opioid Receptor: Synthesis and Characterization of (11)C-LY2459989.

Fluorine-18-Labeled Antagonist for PET Imaging of Kappa Opioid Receptors.

Consensus nomenclature for in vivo imaging of reversibly binding radioligands.

Kinetic modeling of (11)C-LY2795050, a novel antagonist radiotracer for PET imaging of the kappa opioid receptor in humans.

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140-146

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scholarly article

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10.2967/JNUMED.117.195586

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English

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M Naganawa

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2017-07-26T00:00:00Z

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28747521

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Novel 18F-Labeled κ-Opioid Receptor Antagonist as PET Radiotracer: Synthesis and In Vivo Evaluation of 18F-LY2459989 in Nonhuman Primates.

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P2860

P2860

Novel 18F-Labeled κ-Opioid Receptor Antagonist as PET Radiotracer: Synthesis and In Vivo Evaluation of 18F-LY2459989 in Nonhuman Primates.

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