Signal transduction pathways regulated by prolactin and Src result in different conformations of activated Stat5b.

Signal transduction pathways regulated by prolactin and Src result in different conformations of activated Stat5b.

Item
http://www.wikidata.org/entity/Q44350734
Signal transducer and activator of transcription 5b: a new target of breast tumor kinase/protein tyrosine kinase 6Role of STATs as downstream signal transducers in Src family kinase-mediated tumorigenesisActin filament-associated protein 1 is required for cSrc activity and secretory activation in the lactating mammary glandS731 in the transactivation domain modulates STAT5b activity.STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytesThe transcriptional STAT3 is a potential target, whereas transcriptional STAT5A/5B/6 are new biomarkers for prognosis in human breast carcinoma.Glucocorticoids and tumor necrosis factor alpha cooperatively regulate toll-like receptor 2 gene expression.The elements of human cyclin D1 promoter and regulation involved.Prolactin receptor antagonism reduces the clonogenic capacity of breast cancer cells and potentiates doxorubicin and paclitaxel cytotoxicity.Prolactin signals via Stat5 and Oct-1 to the proximal cyclin D1 promoter.Synergistic effect of EMS1-shRNA and sorafenib on proliferation, migration, invasion and endocytosis of SMMC-7721.Co-overexpression of Janus kinase 2 and signal transducer and activator of transcription 5a promotes differentiation of mammary cancer cells through reversal of epithelial-mesenchymal transition.Stat5 promotes homotypic adhesion and inhibits invasive characteristics of human breast cancer cells.Src family kinases interfere with dimerization of STAT5A through a phosphotyrosine-SH2 domain interaction.c-Src tyrosine kinase co-associates with and phosphorylates signal transducer and activator of transcription 5b which mediates the proliferation of normal human B lymphocytes.Rankl Impairs Lactogenic Differentiation Through Inhibition of the Prolactin/Stat5 Pathway at Midgestation.STAT5 signaling is required for the efficient induction and maintenance of CML in mice.
P2860

Signal transduction pathways regulated by prolactin and Src result in different conformations of activated Stat5b.

Item
http://www.wikidata.org/entity/Q44350734
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Signal transduction pathways r ...... ormations of activated Stat5b.
@en
Signal transduction pathways r ...... ormations of activated Stat5b.
@nl
type
label
Signal transduction pathways r ...... ormations of activated Stat5b.
@en
Signal transduction pathways r ...... ormations of activated Stat5b.
@nl
prefLabel
Signal transduction pathways r ...... ormations of activated Stat5b.
@en
Signal transduction pathways r ...... ormations of activated Stat5b.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Signal transduction pathways r ...... ormations of activated Stat5b.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698