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Molecular basis for the progeroid variant of Ehlers-Danlos syndrome. Identification and characterization of two mutations in galactosyltransferase I geneMolecular cloning and expression of mouse GD1alpha/GT1aalpha/GQ1balpha synthase (ST6GalNAc VI) geneMolecular cloning of globotriaosylceramide/CD77 synthase, a glycosyltransferase that initiates the synthesis of globo series glycosphingolipidsRegulation of type 1 protein phosphatase/inhibitor-2 complex by glycogen synthase kinase-3beta in intact cellsAn Eps homology (EH) domain protein that binds to the Ral-GTPase target, RalBP1Complex formation of Plk1 and INCENP required for metaphase-anaphase transitionMolecular cloning of brain-specific GD1alpha synthase (ST6GalNAc V) containing CAG/Glutamine repeatsMitotic kinase Aurora-B is regulated by SUMO-2/3 conjugation/deconjugation during mitosisTargeted disruption of Gb3/CD77 synthase gene resulted in the complete deletion of globo-series glycosphingolipids and loss of sensitivity to verotoxinsExpression cloning of human globoside synthase cDNAs. Identification of beta 3Gal-T3 as UDP-N-acetylgalactosamine:globotriaosylceramide beta 1,3-N-acetylgalactosaminyltransferase.Impaired hypoglossal nerve regeneration in mutant mice lacking complex gangliosides: down-regulation of neurotrophic factors and receptors as possible mechanisms.The blood group P1 synthase gene is identical to the Gb3/CD77 synthase gene. A clue to the solution of the P1/P2/p puzzle.Mechanism of Aurora-B degradation and its dependency on intact KEN and A-boxes: identification of an aneuploidy-promoting propertyGanglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells.Loss of CpG methylation is strongly correlated with loss of histone H3 lysine 9 methylation at DMR-LIT1 in patients with Beckwith-Wiedemann syndrome.DNA-RNA hybrid formation mediates RNAi-directed heterochromatin formation.Hairpin RNA induces secondary small interfering RNA synthesis and silencing in trans in fission yeast.Raf1 Is a DCAF for the Rik1 DDB1-like protein and has separable roles in siRNA generation and chromatin modificationPhosphorylation of Ser-446 determines stability of MKP-7.Expression profile of LIT1/KCNQ1OT1 and epigenetic status at the KvDMR1 in colorectal cancers.Gene amplification and overexpression of PRDM14 in breast cancers.Splicing factors facilitate RNAi-directed silencing in fission yeast.Synthetic heterochromatin bypasses RNAi and centromeric repeats to establish functional centromeres.Trichoplein and Aurora A block aberrant primary cilia assembly in proliferating cells.Cdc2p controls the forkhead transcription factor Fkh2p by phosphorylation during sexual differentiation in fission yeastNucleophosmin: a versatile molecule associated with hematological malignancies.Overexpression of caveolin-1 in a human melanoma cell line results in dispersion of ganglioside GD3 from lipid rafts and alteration of leading edges, leading to attenuation of malignant properties.A chromodomain protein, Chp1, is required for the establishment of heterochromatin in fission yeast.Metastatic potential of mouse Lewis lung cancer cells is regulated via ganglioside GM1 by modulating the matrix metalloprotease-9 localization in lipid rafts.PIAS proteins are involved in the SUMO-1 modification, intracellular translocation and transcriptional repressive activity of RET finger protein.The essential role of histone H3 Lys9 di-methylation and MeCP2 binding in MGMT silencing with poor DNA methylation of the promoter CpG island.Epigenetic inactivation of class II transactivator (CIITA) is associated with the absence of interferon-gamma-induced HLA-DR expression in colorectal and gastric cancer cells.Overexpressed GM1 suppresses nerve growth factor (NGF) signals by modulating the intracellular localization of NGF receptors and membrane fluidity in PC12 cells.GD3 synthase gene expression in PC12 cells results in the continuous activation of TrkA and ERK1/2 and enhanced proliferation.The nuclear scaffold protein SAF-A is required for kinetochore-microtubule attachment and contributes to the targeting of Aurora-A to mitotic spindles.Mitotic regulation of the stability of microtubule plus-end tracking protein EB3 by ubiquitin ligase SIAH-1 and Aurora mitotic kinases.Analysis of the role of Aurora B on the chromosomal targeting of condensin I.Role of DNA methylation and histone H3 lysine 27 methylation in tissue-specific imprinting of mouse Grb10.Usage of tautomycetin, a novel inhibitor of protein phosphatase 1 (PP1), reveals that PP1 is a positive regulator of Raf-1 in vivo.Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation.
P50
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P50
description
Japanese biochemist
@en
biochemicus
@nl
name
Takeshi Urano
@ast
Takeshi Urano
@en
Takeshi Urano
@es
Takeshi Urano
@nl
type
label
Takeshi Urano
@ast
Takeshi Urano
@en
Takeshi Urano
@es
Takeshi Urano
@nl
prefLabel
Takeshi Urano
@ast
Takeshi Urano
@en
Takeshi Urano
@es
Takeshi Urano
@nl
P106
P1153
7201420574
P21
P31
P496
0000-0003-3383-3554
P569
2000-01-01T00:00:00Z