Importance of conserved N-domain residues Thr441, Glu442, Lys515, Arg560, and Leu562 of sarcoplasmic reticulum Ca2+-ATPase for MgATP binding and subsequent catalytic steps. Plasticity of the nucleotide-binding site.
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Solution structure of the N-domain of Wilson disease protein: distinct nucleotide-binding environment and effects of disease mutationsCyclopiazonic Acid Is Complexed to a Divalent Metal Ion When Bound to the Sarcoplasmic Reticulum Ca2+-ATPaseCarbonylation contributes to SERCA2a activity loss and diastolic dysfunction in a rat model of type 1 diabetesConformational Transitions and Alternating-Access Mechanism in the Sarcoplasmic Reticulum Calcium Pump.Roles of conserved P domain residues and Mg2+ in ATP binding in the ground and Ca2+-activated states of sarcoplasmic reticulum Ca2+-ATPase.Modulatory ATP binding affinity in intermediate states of E2P dephosphorylation of sarcoplasmic reticulum Ca2+-ATPase.Gating of TRP channels: a voltage connection?Concerted conformational effects of Ca2+ and ATP are required for activation of sequential reactions in the Ca2+ ATPase (SERCA) catalytic cycle.CRISPR-directed mitotic recombination enables genetic mapping without crosses.Protective effects of Hsp70 on the structure and function of SERCA2a expressed in HEK-293 cells during heat stress.Molecular modelling of the nucleotide-binding domain of Wilson's disease protein: location of the ATP-binding site, domain dynamics and potential effects of the major disease mutations.Decavanadate modulates gating of TRPM4 cation channels.Dissection of the functional differences between sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) 1 and 2 isoforms and characterization of Darier disease (SERCA2) mutants by steady-state and transient kinetic analyses.Probing nucleotide-binding effects on backbone dynamics and folding of the nucleotide-binding domain of the sarcoplasmic/endoplasmic-reticulum Ca2+-ATPase.Modulatory and catalytic modes of ATP binding by the calcium pumpThe nucleotide-binding domain of the Zn2+-transporting P-type ATPase from Escherichia coli carries a glycine motif that may be involved in binding of ATP.Deletions of any single residues in Glu40-Ser48 loop connecting a domain and the first transmembrane helix of sarcoplasmic reticulum Ca(2+)-ATPase result in almost complete inhibition of conformational transition and hydrolysis of phosphoenzyme inteThe amino acid sequence 442GDASE446 in Na/K-ATPase is an important motif in forming the high and low affinity ATP binding pockets.Critical interaction of actuator domain residues arginine 174, isoleucine 188, and lysine 205 with modulatory nucleotide in sarcoplasmic reticulum Ca2+-ATPase.Crystal structure of the calcium pump with a bound ATP analogue.The holo-form of the nucleotide binding domain of the KdpFABC complex from Escherichia coli reveals a new binding mode.Mutations Phe785Leu and Thr618Met in Na+,K+-ATPase, associated with familial rapid-onset dystonia parkinsonism, interfere with Na+ interaction by distinct mechanisms.Comprehensive analysis of expression and function of 51 sarco(endo)plasmic reticulum Ca2+-ATPase mutants associated with Darier disease.ATP-binding modes and functionally important interdomain bonds of sarcoplasmic reticulum Ca2+-ATPase revealed by mutation of glycine 438, glutamate 439, and arginine 678.
P2860
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P2860
Importance of conserved N-domain residues Thr441, Glu442, Lys515, Arg560, and Leu562 of sarcoplasmic reticulum Ca2+-ATPase for MgATP binding and subsequent catalytic steps. Plasticity of the nucleotide-binding site.
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2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
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2003年学术文章
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2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
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2003年學術文章
@zh-hant
name
Importance of conserved N-doma ...... f the nucleotide-binding site.
@en
Importance of conserved N-doma ...... f the nucleotide-binding site.
@nl
type
label
Importance of conserved N-doma ...... f the nucleotide-binding site.
@en
Importance of conserved N-doma ...... f the nucleotide-binding site.
@nl
prefLabel
Importance of conserved N-doma ...... f the nucleotide-binding site.
@en
Importance of conserved N-doma ...... f the nucleotide-binding site.
@nl
P2093
P2860
P356
P1476
Importance of conserved N-doma ...... f the nucleotide-binding site.
@en
P2093
Bente Vilsen
David B McIntosh
David G Woolley
Jens Peter Andersen
Johannes D Clausen
P2860
P304
20245-20258
P356
10.1074/JBC.M301122200
P407
P577
2003-03-20T00:00:00Z