Production of "authentic" poliovirus RNA-dependent RNA polymerase (3D(pol)) by ubiquitin-protease-mediated cleavage in Escherichia coli.
about
Human rhinovirus type 14 gain-of-function mutants for oriI utilization define residues of 3C(D) and 3Dpol that contribute to assembly and stability of the picornavirus VPg uridylylation complexStructural dynamics as a contributor to error-prone replication by an RNA-dependent RNA polymerase.Crystal Structure of Poliovirus 3CD Protein: Virally Encoded Protease and Precursor to the RNA-Dependent RNA PolymeraseStructural basis for active site closure by the poliovirus RNA-dependent RNA polymeraseDeubiquitinase function of arterivirus papain-like protease 2 suppresses the innate immune response in infected host cellsStructures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contactsCrystal Structure of the full-length Japanese encephalitis virus NS5 reveals a conserved methyltransferase-polymerase interfacePoliovirus RNA-dependent RNA polymerase (3Dpol): structural, biochemical, and biological analysis of conserved structural motifs A and BDipyridamole reversibly inhibits mengovirus RNA replicationViral reorganization of the secretory pathway generates distinct organelles for RNA replication.Calicivirus translation initiation requires an interaction between VPg and eIF 4 E.Perturbation in the conserved methyltransferase-polymerase interface of flavivirus NS5 differentially affects polymerase initiation and elongationStructural basis of viral RNA-dependent RNA polymerase catalysis and translocationRETRACTED: Norovirus RNA synthesis is modulated by an interaction between the viral RNA-dependent RNA polymerase and the major capsid protein, VP1.Norovirus proteinase-polymerase and polymerase are both active forms of RNA-dependent RNA polymeraseCytoplasmic viral RNA-dependent RNA polymerase disrupts the intracellular splicing machinery by entering the nucleus and interfering with Prp8Development and validation of a high-throughput screening assay for the hepatitis C virus p7 viroporin.Proteinase-polymerase precursor as the active form of feline calicivirus RNA-dependent RNA polymerase.Expanding the proteome of an RNA virus by phosphorylation of an intrinsically disordered viral protein.RNA virus population diversity, an optimum for maximal fitness and virulence.Crystal structure of the Middle East respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppressionStructure-function relationships underlying the replication fidelity of viral RNA-dependent RNA polymerases.Remote site control of an active site fidelity checkpoint in a viral RNA-dependent RNA polymerase.Two proton transfers in the transition state for nucleotidyl transfer catalyzed by RNA- and DNA-dependent RNA and DNA polymerasesMutational robustness of an RNA virus influences sensitivity to lethal mutagenesis.Lethal mutagenesis of poliovirus mediated by a mutagenic pyrimidine analogue.Cell-Based High-Throughput Screening Assay Identifies 2',2'-Difluoro-2'-deoxycytidine Gemcitabine as a Potential Antipoliovirus Agent.Small ubiquitin-like modifying protein isopeptidase assay based on poliovirus RNA polymerase activity.Synthesis and antiviral activity of 5-substituted cytidine analogues: identification of a potent inhibitor of viral RNA-dependent RNA polymerases.Coxsackievirus B3 mutator strains are attenuated in vivo.Motif D of viral RNA-dependent RNA polymerases determines efficiency and fidelity of nucleotide additionPicornavirus genome replication: assembly and organization of the VPg uridylylation ribonucleoprotein (initiation) complex.Structure-function relationships of the viral RNA-dependent RNA polymerase: fidelity, replication speed, and initiation mechanism determined by a residue in the ribose-binding pocketA Polymerase mechanism-based strategy for viral attenuation and vaccine development.Lethal mutagenesis of picornaviruses with N-6-modified purine nucleoside analogues.Poliovirus RNA-dependent RNA polymerase (3Dpol): kinetic, thermodynamic, and structural analysis of ribonucleotide selection.Poliovirus RNA-dependent RNA polymerase (3Dpol): pre-steady-state kinetic analysis of ribonucleotide incorporation in the presence of Mn2+.Poliovirus RNA-dependent RNA polymerase (3Dpol): pre-steady-state kinetic analysis of ribonucleotide incorporation in the presence of Mg2+.Polyprotein context regulates the activity of poliovirus 2CATPase bound to bilayer nanodiscs.Human mitochondrial RNA polymerase: evaluation of the single-nucleotide-addition cycle on synthetic RNA/DNA scaffolds.
P2860
Q24681570-396295E4-5B76-47C5-8EB4-8087D594D0E0Q27313945-55461D5A-2B73-4DDD-BA70-B4AFA694923CQ27643650-A90E6CB4-6B26-4E91-91FC-D59BC6036ADDQ27666339-594E647D-F9AD-46BE-9EEF-6594BA0462B1Q27676341-ADDEFC8E-132B-4C32-8658-DD6E9A9B3100Q27678100-B6542A1A-14DC-4F27-BAE4-C78DD5B4AC12Q27679697-98D25B5A-FE5A-4ED1-8253-9E1551C9C851Q28145203-9C716A6B-F519-438E-8285-7870EFCA3E04Q28267559-CE8C9594-EAAB-4BB3-AA8D-4F365A178359Q28283814-62F00ECC-F05C-45CF-A8C9-2BD5B468B32CQ28507110-33188E82-0DF2-4137-910D-16BF18F099EAQ28651848-AC486935-E716-40E0-9E45-878AE4CAB8CAQ28829956-F7305572-F3D4-4686-8694-9D8136B2D5D3Q30155275-DA481D63-DBA1-40B2-A10A-9ECCBB257816Q33781094-50C39306-23EB-4F11-8D27-A8649BF6C1D2Q33812774-2F5A5BE8-F598-4252-BF36-22A5AA8A476DQ33827260-01FC1B48-8AFB-45A6-89BD-3210FCB48862Q33836064-F265A6A3-F737-4CD1-918F-BCEA0F963786Q34107289-CD1F5A21-B471-4631-96A6-D988FFC72EF9Q34396730-E39AA905-803B-4AEB-8305-7C8EBABFF6ACQ34683256-C6DDF253-7A53-43AC-8D42-AA8A08469BD5Q34992586-E590151F-8DBD-4BBB-8442-E6BEFA559D97Q35012405-5066F49E-CBC2-4757-8D39-972A721776D2Q35721277-B45006B8-809B-46F2-B04B-C0BAFCCC7BDCQ35826103-98B39762-DFA3-46DF-81B7-BB7A306ADDBBQ36099285-B7A129D4-B035-4138-9DEB-379E4660DB11Q36161679-7E0F6829-1C33-4EB4-8570-19BBD44EE2FFQ36168994-DC14A836-661D-4A07-A2F2-64D25B72F948Q36168999-A3DDF221-5268-43C4-9C68-AE0E10D02DB2Q36187182-302B4AC4-CE35-4238-BED7-68241E6ECAC2Q36223299-6A38B763-A387-45C2-8F5F-9E527D1F61BCQ36225116-ED982D60-1EF9-4745-B631-FC143645D786Q36225123-3A014C4A-97CC-4AF1-8DC7-6AB1E5D9F8C6Q36234666-D0D39272-70B0-486A-BCE0-B09FE37DED8EQ36482715-DED6B9D0-E0A3-4ECC-B4D5-141241873193Q36718286-AB658AB1-0429-4A7E-BFBE-20CE2D5AAB02Q36718297-E5E35D52-948D-4C22-A51D-94D1AB633197Q36718302-9303C9CE-0A77-4371-A38A-9D66AB27F389Q36827409-69586D83-AC52-47A3-9BD6-C91CD38BCD49Q36972846-04B787A7-B430-4749-9CC1-D8B0FF13296F
P2860
Production of "authentic" poliovirus RNA-dependent RNA polymerase (3D(pol)) by ubiquitin-protease-mediated cleavage in Escherichia coli.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh-hant
name
Production of "authentic" poli ...... cleavage in Escherichia coli.
@en
Production of "authentic" poliovirus RNA-dependent RNA polymerase
@nl
type
label
Production of "authentic" poli ...... cleavage in Escherichia coli.
@en
Production of "authentic" poliovirus RNA-dependent RNA polymerase
@nl
prefLabel
Production of "authentic" poli ...... cleavage in Escherichia coli.
@en
Production of "authentic" poliovirus RNA-dependent RNA polymerase
@nl
P2093
P356
P1476
Production of "authentic" poli ...... d cleavage in Escherichia coli
@en
P2093
P304
P356
10.1006/PREP.1999.1100
P577
1999-10-01T00:00:00Z