Inducible, brain region-specific expression of a dominant negative mutant of c-Jun in transgenic mice decreases sensitivity to cocaine.
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Transcriptional mechanisms of drug addictionMolecular neurobiology of addiction: what’s all the (Δ)FosB about?ΔFosB in the nucleus accumbens is critical for reinforcing effects of sexual rewardReview. Transcriptional mechanisms of addiction: role of DeltaFosBDistinct patterns of DeltaFosB induction in brain by drugs of abuseBrain regional differences in CB1 receptor adaptation and regulation of transcriptionPhosphorylation of DARPP-32 at Threonine-34 is required for cocaine actionQuinine enhances the behavioral stimulant effect of cocaine in mice.Striatal overexpression of DeltaJunD resets L-DOPA-induced dyskinesia in a primate model of Parkinson disease.Gene Network Dysregulation in Dorsolateral Prefrontal Cortex Neurons of Humans with Cocaine Use Disorder.DeltaFosB in brain reward circuits mediates resilience to stress and antidepressant responses.Threonine 149 phosphorylation enhances ΔFosB transcriptional activity to control psychomotor responses to cocaine.Delta FosB and AP-1-mediated transcription modulate cannabinoid CB₁ receptor signaling and desensitization in striatal and limbic brain regions.Regulation of gene expression and cocaine reward by CREB and DeltaFosB.∆FosB: a transcriptional regulator of stress and antidepressant responses.A Role for Mitogen- and Stress-Activated Kinase 1 in L-DOPA-Induced Dyskinesia and ∆FosB ExpressionPSMC5, a 19S Proteasomal ATPase, Regulates Cocaine Action in the Nucleus AccumbensEffect of ΔFosB overexpression on opioid and cannabinoid receptor-mediated signaling in the nucleus accumbens.FosB is essential for the enhancement of stress tolerance and antagonizes locomotor sensitization by ΔFosB.Preventive role of social interaction for cocaine conditioned place preference: correlation with FosB/DeltaFosB and pCREB expression in rat mesocorticolimbic areasSerum response factor and cAMP response element binding protein are both required for cocaine induction of ΔFosB.The "ups and downs" of signaling cascades in addiction.Acute and chronic dose-response effect of methylphenidate on ventral tegmental area neurons correlated with animal behavior.Behavioral and structural responses to chronic cocaine require a feedforward loop involving ΔFosB and calcium/calmodulin-dependent protein kinase II in the nucleus accumbens shell.Neuroplasticity mediated by altered gene expression.Inhibiting activator protein-1 activity alters cocaine-induced gene expression and potentiates sensitization.Essential role of SIRT1 signaling in the nucleus accumbens in cocaine and morphine action.Delta FosB overexpression in the nucleus accumbens enhances sexual reward in female Syrian hamsters.ΔJunD overexpression in the nucleus accumbens prevents sexual reward in female Syrian hamstersThe striatal balancing act in drug addiction: distinct roles of direct and indirect pathway medium spiny neurons.Neuroplasticity in addiction: cellular and transcriptional perspectives.Small molecule screening identifies regulators of the transcription factor ΔFosBEnergy expenditure and bone formation share a common sensitivity to AP-1 transcription in the hypothalamus.Δ9-Tetrahydrocannabinol Experience Influences ΔFosB and Downstream Gene Expression in Prefrontal Cortex.Regulation of fosB and DeltafosB mRNA expression: in vivo and in vitro studies.DeltaFosB induction in orbitofrontal cortex potentiates locomotor sensitization despite attenuating the cognitive dysfunction caused by cocaine.An essential role for DeltaFosB in the nucleus accumbens in morphine action.ΔFosB Decreases Excitability of Dorsal Hippocampal CA1 Neurons
P2860
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P2860
Inducible, brain region-specific expression of a dominant negative mutant of c-Jun in transgenic mice decreases sensitivity to cocaine.
description
2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年学术文章
@zh-hans
2003年学术文章
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name
Inducible, brain region-specif ...... reases sensitivity to cocaine.
@en
Inducible, brain region-specif ...... reases sensitivity to cocaine.
@nl
type
label
Inducible, brain region-specif ...... reases sensitivity to cocaine.
@en
Inducible, brain region-specif ...... reases sensitivity to cocaine.
@nl
prefLabel
Inducible, brain region-specif ...... reases sensitivity to cocaine.
@en
Inducible, brain region-specif ...... reases sensitivity to cocaine.
@nl
P2093
P1433
P1476
Inducible, brain region-specif ...... reases sensitivity to cocaine.
@en
P2093
McNeish JD
Nestler EJ
Peakman MC
P356
10.1016/S0006-8993(03)02230-3
P407
P577
2003-04-01T00:00:00Z