Identification of an inhibitor binding site of poly(ADP-ribose) glycohydrolase.
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The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolaseStructures of the Human Poly (ADP-Ribose) Glycohydrolase Catalytic Domain Confirm Catalytic Mechanism and Explain Inhibition by ADP-HPD DerivativesStructure of mammalian poly(ADP-ribose) glycohydrolase reveals a flexible tyrosine clasp as a substrate-binding elementCrystallographic and biochemical analysis of the mouse poly(ADP-ribose) glycohydrolaseFailure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality.Identification of a regulatory segment of poly(ADP-ribose) glycohydrolase.Inhibition of the transient receptor potential melastatin-2 channel causes increased DNA damage and decreased proliferation in breast adenocarcinoma cellsStructural biology of the writers, readers, and erasers in mono- and poly(ADP-ribose) mediated signaling.The recognition and removal of cellular poly(ADP-ribose) signals.Identification of three critical acidic residues of poly(ADP-ribose) glycohydrolase involved in catalysis: determining the PARG catalytic domain.Mono-galloyl glucose derivatives are potent poly(ADP-ribose) glycohydrolase (PARG) inhibitors and partially reduce PARP-1-dependent cell death.
P2860
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P2860
Identification of an inhibitor binding site of poly(ADP-ribose) glycohydrolase.
description
2003 nî lūn-bûn
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2003年の論文
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name
Identification of an inhibitor binding site of poly
@nl
Identification of an inhibitor binding site of poly(ADP-ribose) glycohydrolase.
@en
type
label
Identification of an inhibitor binding site of poly
@nl
Identification of an inhibitor binding site of poly(ADP-ribose) glycohydrolase.
@en
prefLabel
Identification of an inhibitor binding site of poly
@nl
Identification of an inhibitor binding site of poly(ADP-ribose) glycohydrolase.
@en
P2093
P356
P1433
P1476
Identification of an inhibitor binding site of poly(ADP-ribose) glycohydrolase.
@en
P2093
Chandra N Patel
David W Koh
James T Slama
Marcos A Oliveira
Myron K Jacobson
Sushma Ramsinghani
P304
P356
10.1021/BI0272048
P407
P577
2003-05-01T00:00:00Z