DNA-protein cross-link formation mediated by oxanine. A novel genotoxic mechanism of nitric oxide-induced DNA damage.
about
Repair activity of base and nucleotide excision repair enzymes for guanine lesions induced by nitrosative stress.Chemical synthesis and thermodynamic characterization of oxanine-containing oligodeoxynucleotides.Looking beneath the surface to determine what makes DNA damage deleterious5-Hydroxy-5-methylhydantoin DNA lesion, a molecular trap for DNA glycosylasesDifferential specificity of human and Escherichia coli endonuclease III and VIII homologues for oxidative base lesionsOxanine DNA glycosylase activity from Mammalian alkyladenine glycosylaseRepair of DNA-polypeptide crosslinks by human excision nuclease.Reactivity of Nucleic Acid Radicals.Synthesis of site-specific DNA-protein conjugates and their effects on DNA replicationInhibition of short patch and long patch base excision repair by an oxidized abasic site.Rapid DNA-protein cross-linking and strand scission by an abasic site in a nucleosome core particle.Solution structure and stability of the DNA undecamer duplexes containing oxanine mismatch.Rapid determination of the active fraction of DNA repair glycosylases: a novel fluorescence assay for trapped intermediates.T7 RNA polymerases backed up by covalently trapped proteins catalyze highly error prone transcriptionDNA-Protein Cross-Links: Formation, Structural Identities, and Biological OutcomesTranslocation and stability of replicative DNA helicases upon encountering DNA-protein cross-links.Elucidating DNA damage and repair processes by independently generating reactive and metastable intermediates.DNA tandem lesion repair by strand displacement synthesis and nucleotide excision repair.Relatively small increases in the steady-state levels of nucleobase deamination products in DNA from human TK6 cells exposed to toxic levels of nitric oxideSynthesis of sequence-specific DNA-protein conjugates via a reductive amination strategy.Genetic analysis of repair and damage tolerance mechanisms for DNA-protein cross-links in Escherichia coli.DNA interstrand cross-link formation by the 1,4-dioxobutane abasic lesionHomologous recombination but not nucleotide excision repair plays a pivotal role in tolerance of DNA-protein cross-links in mammalian cells.Abasic and oxidized abasic site reactivity in DNA: enzyme inhibition, cross-linking, and nucleosome catalyzed reactions.Upregulation of N-acetylaspartic acid induces oxidative stress to contribute in disease pathophysiology.Cleavage of deoxyoxanosine-containing oligodeoxyribonucleotides by bacterial endonuclease V.Risky repair: DNA-protein crosslinks formed by mitochondrial base excision DNA repair enzymes acting on free radical lesions.Biochemical evaluation of genotoxic biomarkers for 2-deoxyribonolactone-mediated cross-link formation with histones.Characterization of the deoxyguanosine-lysine cross-link of methylglyoxal.Direct immobilization of DNA oligomers onto the amine-functionalized glass surface for DNA microarray fabrication through the activation-free reaction of oxanine.Importance of phenols structure on their activity as antinitrosating agents: A kinetic study.Bypass of DNA-Protein Cross-links Conjugated to the 7-Deazaguanine Position of DNA by Translesion Synthesis PolymerasesSynthesis of 2'-deoxyoxanosine from 2'-deoxyguanosine, conversion to its phosphoramidite, and incorporation into oxanine-containing oligodeoxynucleotides.Long-patch base excision DNA repair of 2-deoxyribonolactone prevents the formation of DNA-protein cross-links with DNA polymerase beta.Biophysical stability and enzymatic recognition of oxanine in DNA.Chemistry of Inflammation and DNA Damage: Biological Impact of Reactive Nitrogen SpeciesFormation of DNA‐protein cross‐links mediated by C1'‐oxidized abasic lesion in mouse embryonic fibroblast cell‐free extracts
P2860
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P2860
DNA-protein cross-link formation mediated by oxanine. A novel genotoxic mechanism of nitric oxide-induced DNA damage.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
DNA-protein cross-link formati ...... tric oxide-induced DNA damage.
@en
DNA-protein cross-link formati ...... tric oxide-induced DNA damage.
@nl
type
label
DNA-protein cross-link formati ...... tric oxide-induced DNA damage.
@en
DNA-protein cross-link formati ...... tric oxide-induced DNA damage.
@nl
prefLabel
DNA-protein cross-link formati ...... tric oxide-induced DNA damage.
@en
DNA-protein cross-link formati ...... tric oxide-induced DNA damage.
@nl
P2093
P2860
P356
P1476
DNA-protein cross-link formati ...... tric oxide-induced DNA damage.
@en
P2093
Aya Masaoka
Hiroaki Terato
Hiroshi Ide
Keisuke Makino
Kenjiro Asagoshi
Miho Mukuta
Toshiaki Nakano
Toshinori Suzuki
Yoshihiko Ohyama
P2860
P304
25264-25272
P356
10.1074/JBC.M212847200
P407
P577
2003-04-27T00:00:00Z