The effect of valproic acid on drug and steroid glucuronidation by expressed human UDP-glucuronosyltransferases.
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Dosing Recommendations for Concomitant Medications During 3D Anti-HCV TherapyAnti-cancer drugs elicit re-expression of UDP-glucuronosyltransferases in melanoma cellsValproic acid pathway: pharmacokinetics and pharmacodynamics.High concentrations of commonly used drugs can inhibit the in vitro glucuronidation of bisphenol A and nonylphenol in rats.Required propofol dose for anesthesia and time to emerge are affected by the use of antiepileptics: prospective cohort study.Requirements for generic anti-epileptic medicines: a regulatory perspective.Influence of valproate on the required dose of propofol for anesthesia during electroconvulsive therapy of bipolar affective disorder patients.Soybean greatly reduces valproic acid plasma concentrations: a food-drug interaction studyThe effect of carbapenem antibiotics on plasma concentrations of valproic acid.Functional impact and prevalence of polymorphisms involved in the hepatic glucuronidation of valproic acid.Substrate selectivity of human intestinal UDP-glucuronosyltransferases (UGTs): in silico and in vitro insights.Pharmacokinetic Interactions between Valproic Acid and Lorazepam (PIVOtAL Study): A Review of Site-Specific Practices.Cytochrome P450-mediated metabolism of triclosan attenuates its cytotoxicity in hepatic cells.Effect of aging on glucuronidation of valproic acid in human liver microsomes and the role of UDP-glucuronosyltransferase UGT1A4, UGT1A8, and UGT1A10Effects of ketoconazole and valproic acid on the pharmacokinetics of the next generation NNRTI, lersivirine (UK-453,061), in healthy adult subjects.Variation in glucuronidation of lamotrigine in human liver microsomes.Influence of UDP-glucuronosyltransferase polymorphisms on valproic acid pharmacokinetics in Chinese epilepsy patients.Phenobarbital and phenytoin increased acetaminophen hepatotoxicity due to inhibition of UDP-glucuronosyltransferases in cultured human hepatocytes.Possible interaction between lopinavir/ritonavir and valproic Acid exacerbates bipolar disorder.The influence of oral VPA on the required dose of propofol for sedation during dental treatment in patients with mental retardation: a prospective observer-blinded cohort study.A population pharmacokinetic model of valproic acid in pediatric patients with epilepsy: a non-linear pharmacokinetic model based on protein-binding saturation.Expression of UGT1A subfamily in rat brain.Association of genetic variants in six candidate genes with valproic acid therapy optimization.CYP2C9 polymorphisms in epilepsy: influence on phenytoin treatment.Mechanisms and the clinical relevance of complex drug-drug interactions
P2860
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P2860
The effect of valproic acid on drug and steroid glucuronidation by expressed human UDP-glucuronosyltransferases.
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2003年学术文章
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name
The effect of valproic acid on ...... UDP-glucuronosyltransferases.
@en
The effect of valproic acid on ...... UDP-glucuronosyltransferases.
@nl
type
label
The effect of valproic acid on ...... UDP-glucuronosyltransferases.
@en
The effect of valproic acid on ...... UDP-glucuronosyltransferases.
@nl
prefLabel
The effect of valproic acid on ...... UDP-glucuronosyltransferases.
@en
The effect of valproic acid on ...... UDP-glucuronosyltransferases.
@nl
P2093
P1476
The effect of valproic acid on ...... UDP-glucuronosyltransferases.
@en
P2093
Brian Burchell
Brian T Ethell
Gail D Anderson
P304
P356
10.1016/S0006-2952(03)00076-5
P407
P577
2003-05-01T00:00:00Z