Psammaplins from the sponge Pseudoceratina purpurea: inhibition of both histone deacetylase and DNA methyltransferase.
about
Marine low molecular weight natural products as potential cancer preventive compoundsHistone deacetylase inhibitors for cancer therapy: An evolutionarily ancient resistance response may explain their limited successThe marine bromotyrosine derivativesSantacruzamate A, a potent and selective histone deacetylase inhibitor from the Panamanian marine cyanobacterium cf. Symploca spPsammaplin A as a general activator of cell-based signaling assays via HDAC inhibition and studies on some bromotyrosine derivativesAntiplasmodial activities of homogentisic acid derivative protein kinase inhibitors isolated from a Vanuatu marine sponge Pseudoceratina spPreclinical studies of chemotherapy using histone deacetylase inhibitors in endometrial cancerA selective account of effective paradigms and significant outcomes in the discovery of inspirational marine natural products.A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation.Epigenetic changes induced by curcumin and other natural compounds.Current limitations and future opportunities for epigenetic therapies.Psammaplin a improves development and quality of somatic cell nuclear transfer mouse embryos.Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor.Epigenetic drugs against cancer: an evolving landscape.Identification of kazinol Q, a natural product from Formosan plants, as an inhibitor of DNA methyltransferase.DNA demethylating antineoplastic strategies: a comparative point of viewBiological targets and mechanisms of action of natural products from marine cyanobacteria.Epigenetic therapy for breast cancer.Preclinical studies on histone deacetylase inhibitors as therapeutic reagents for endometrial and ovarian cancers.Targeting epigenetic regulatory mechanisms in cancer chemoprevention.Emerging drugs for the treatment of myelodysplastic syndrome.Additional insights on the bastadins: isolation of analogues from the sponge Ianthella cf. reticulata and exploration of the oxime configurations.Subereamolline A as a potent breast cancer migration, invasion and proliferation inhibitor and bioactive dibrominated alkaloids from the Red Sea sponge Pseudoceratina arabicaMarine-derived angiogenesis inhibitors for cancer therapy.DNA-intercalators causing rapid re-expression of methylated and silenced genes in cancer cellsInduction of apoptosis in endometrial cancer cells by psammaplysene A involves FOXO1.Discovery and mechanism of natural products as modulators of histone acetylation.Discovery and characterization of Isofistularin-3, a marine brominated alkaloid, as a new DNA demethylating agent inducing cell cycle arrest and sensitization to TRAIL in cancer cells.Potential of DNMT and its Epigenetic Regulation for Lung Cancer Therapy.The Bengamides: A Mini-Review of Natural Sources, Analogues, Biological Properties, Biosynthetic Origins, and Future Prospects.Survey of marine natural product structure revisions: a synergy of spectroscopy and chemical synthesis.The application of delivery systems for DNA methyltransferase inhibitors.Targeting epigenetic networks with polypharmacology: a new avenue to tackle cancer.DNA methyltransferase inhibitors in cancer: a chemical and therapeutic patent overview and selected clinical studies.Cancers with wrong HATs: the impact of acetylation.Perspectives on natural product epigenetic modulators in chemical biology and medicine.Natural product and natural product derived drugs in clinical trials.Biological and biochemical modulation of DNA methylation.Natural products as zinc-dependent histone deacetylase inhibitors.Natural Compounds: DNA Methyltransferase Inhibitors in Oral Squamous Cell Carcinoma.
P2860
Q27025660-5515C181-87EB-4B12-B5C8-ADAD5207DCB8Q28822336-E64E3916-47AE-45FD-A984-F8C700D35AC3Q28830285-FF855B23-A5F3-4D9E-A1DF-9D5EAC0DB197Q30684975-1A64CA4F-5356-409A-ABCB-11526E0ECF44Q33385924-9C57A57D-2D98-4D26-AB3B-2EFC605077C3Q33526249-0B8B7BD9-87ED-4563-8F25-555CEF488F3EQ33651762-732D6550-FFD5-4CCC-B140-1209B8CD0BB7Q33721944-526F5581-9BDA-4414-9C67-F3EF1BCFF069Q33901844-6655DBF7-E540-4A09-94DD-7B6CA9DF763EQ34180255-15AF32EF-E15A-44CF-99DB-431D144B22B1Q34195077-E0738E9E-D5D6-4818-8257-0FB9C84C13ACQ34231378-8E2A71F0-4AEC-4D77-8717-DF26AD3B0F02Q34257533-C49A09D6-F03E-4A46-834C-F63DE2F3EEB8Q34431964-80D62553-C855-4DA5-8AD5-FD11FA31CC1EQ34601752-B6AF2992-C1EA-4B4D-8A40-3B4D5F41A635Q34972245-02D8BBFB-5118-43E3-B4B9-F4D5C62964A7Q35130835-518EB48E-ED07-4B4E-BE96-248CDAEF391DQ35162148-FE993076-A0F6-4EC9-A129-8DC11A747B35Q35739684-F7F3E994-C643-4897-BA43-12368E1D4AFDQ36150848-90BD2DBD-D962-4D23-B02C-0EF01E511D14Q36219655-9B7D5A85-015B-4875-ADF4-77686A91BD1CQ36365864-DAF3268E-FF30-46BA-88AC-9DD147AE3C7CQ36432325-0DFE4F02-BB58-418F-A954-7C4F5E1D62FAQ36994177-B7211AC7-8F97-41C9-81E8-9E43E603044FQ37016577-8B8F1419-0D0C-46E6-A544-81113EA76B8DQ37144348-0D60A05C-6650-466C-9C9C-B48635AE5047Q37242496-8AA1F56F-0E5D-400E-BC23-7B723F23BD6FQ37269205-02C767B6-E7D9-4A5A-8DF2-565794E7E468Q37313424-FF0A2C62-C63F-4E1E-9708-DB812973C774Q37724092-65982C9E-F499-48F5-BA94-ECC1A15C2A53Q37895765-39B7E09E-8BEB-445B-B379-739622B53B72Q37911496-82E50C1E-4C7D-44F6-866A-1F971E9B0559Q37961798-BEC49D1E-2D7B-4E3C-B66E-FE91237ED85EQ38049175-385335D4-A6C4-4326-A175-E49DEBE4CDE9Q38074618-9E47FE80-CB1E-4173-B921-18F90971ABD4Q38080414-3E78D129-F8A9-44F1-8FA9-74003182F713Q38247457-C59A278F-248E-44D9-9575-5AAF3FD9CB1AQ38296738-5D862C74-AE6B-4E43-ABF3-7FED9F7262B7Q38315538-0FB2D260-51D2-471C-920F-A14E3E9AFC04Q38554299-D0207494-0081-4879-B51E-161FBE31E1DA
P2860
Psammaplins from the sponge Pseudoceratina purpurea: inhibition of both histone deacetylase and DNA methyltransferase.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Psammaplins from the sponge Ps ...... ase and DNA methyltransferase.
@en
Psammaplins from the sponge Ps ...... ase and DNA methyltransferase.
@nl
type
label
Psammaplins from the sponge Ps ...... ase and DNA methyltransferase.
@en
Psammaplins from the sponge Ps ...... ase and DNA methyltransferase.
@nl
prefLabel
Psammaplins from the sponge Ps ...... ase and DNA methyltransferase.
@en
Psammaplins from the sponge Ps ...... ase and DNA methyltransferase.
@nl
P2093
P356
P1476
Psammaplins from the sponge Ps ...... ase and DNA methyltransferase.
@en
P2093
Dennis France
Francis J Schmitz
Gui-Yang-Sheng Wang
Ivette C Piña
Jeffrey T Gautschi
Kenneth W Bair
Larry B Perez
Lidia C Sambucetti
Miranda L Sanders
Phillip Crews
P304
P356
10.1021/JO034248T
P407
P577
2003-05-01T00:00:00Z