Amino acids Glu323, Tyr324, Glu330, and Val331 of factor Va heavy chain are essential for expression of cofactor activity.

Amino acids Glu323, Tyr324, Glu330, and Val331 of factor Va heavy chain are essential for expression of cofactor activity.

Item
http://www.wikidata.org/entity/Q44435259
Contribution of Amino Acid Region 659−663 of Factor Va Heavy Chain to the Activity of Factor Xa within Prothrombinase,Cleavage at both Arg306 and Arg506 is required and sufficient for timely and efficient inactivation of factor Va by activated protein C.Amino acid region 1000-1008 of factor V is a dynamic regulator for the emergence of procoagulant activity.The Dual Regulatory Role of Amino Acids Leu480 and Gln481 of Prothrombin.Mapping of the factor Xa binding site on factor Va by site-directed mutagenesisRole of the acidic hirudin-like COOH-terminal amino acid region of factor Va heavy chain in the enhanced function of prothrombinase.Cooperative regulation of the activity of factor Xa within prothrombinase by discrete amino acid regions from factor Va heavy chain.Contribution of amino acid region 334-335 from factor Va heavy chain to the catalytic efficiency of prothrombinase.The contribution of amino acid region ASP695-TYR698 of factor V to procofactor activation and factor Va function.Identification of a factor Xa-interactive site within residues 337-372 of the factor VIII heavy chain.Exosite-interactive regions in the A1 and A2 domains of factor VIII facilitate thrombin-catalyzed cleavage of heavy chain.Spellbinding Effects of the Acidic COOH-Terminus of Factor Va Heavy Chain on Prothrombinase Activity and Function.Differences in prethrombin-1 activation with human or bovine factor Va can be attributed to the heavy chain.Characterization of a factor Xa binding site on factor Va near the Arg-506 activated protein C cleavage site.Incorporation of factor Va into prothrombinase is required for coordinated cleavage of prothrombin by factor Xa.
P2860

Amino acids Glu323, Tyr324, Glu330, and Val331 of factor Va heavy chain are essential for expression of cofactor activity.

Item
http://www.wikidata.org/entity/Q44435259
description
2003 nî lūn-bûn
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2003年の論文
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name
Amino acids Glu323, Tyr324, Gl ...... pression of cofactor activity.
@en
Amino acids Glu323, Tyr324, Gl ...... pression of cofactor activity.
@nl
type
label
Amino acids Glu323, Tyr324, Gl ...... pression of cofactor activity.
@en
Amino acids Glu323, Tyr324, Gl ...... pression of cofactor activity.
@nl
prefLabel
Amino acids Glu323, Tyr324, Gl ...... pression of cofactor activity.
@en
Amino acids Glu323, Tyr324, Gl ...... pression of cofactor activity.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Amino acids Glu323, Tyr324, Gl ...... pression of cofactor activity.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698