Serine proteases are involved in the pathogenesis of trauma-hemorrhagic shock-induced gut and lung injury.
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Protease activity increases in plasma, peritoneal fluid, and vital organs after hemorrhagic shock in ratsTransmural intestinal wall permeability in severe ischemia after enteral protease inhibition.Mesenteric lymph diversion abrogates 5-lipoxygenase activation in the kidney following trauma and hemorrhagic shockLoss of the intestinal mucus layer in the normal rat causes gut injury but not toxic mesenteric lymph nor lung injuryElimination of C5aR prevents intestinal mucosal damage and attenuates neutrophil infiltration in local and remote organs.Intestinal mucus layer preservation in female rats attenuates gut injury after trauma-hemorrhagic shock.Pancreatic trypsin increases matrix metalloproteinase-9 accumulation and activation during acute intestinal ischemia-reperfusion in the rat.Disruption of the mucosal barrier during gut ischemia allows entry of digestive enzymes into the intestinal wall.The use of animal models to study bacterial translocation during acute pancreatitisSyndecan 1 plays a novel role in enteral glutamine's gut-protective effects of the postischemic gut.Impaired small-bowel barrier integrity in the presence of lumenal pancreatic digestive enzymes leads to circulatory shockEstrogen: a novel therapeutic adjunct for the treatment of trauma-hemorrhage-induced immunological alterations.A journey with Tony Hugli up the inflammatory cascade towards the auto-digestion hypothesisMesenteric lymph duct ligation prevents trauma/hemorrhage shock-induced cardiac contractile dysfunction.Removal of luminal content protects the small intestine during hemorrhagic shock but is not sufficient to prevent lung injury.A simple taurocholate-induced model of severe acute pancreatitis in ratsThe autodigestion hypothesis for shock and multi-organ failure.Autodigestion: Proteolytic Degradation and Multiple Organ Failure in ShockIntraluminal tranexamic acid inhibits intestinal sheddases and mitigates gut and lung injury and inflammation in a rodent model of hemorrhagic shock.The mucus layer is critical in protecting against ischemia-reperfusion-mediated gut injury and in the restitution of gut barrier function.Oxidative modification of the intestinal mucus layer is a critical but unrecognized component of trauma hemorrhagic shock-induced gut barrier failure.The intestinal mucus layer is a critical component of the gut barrier that is damaged during acute pancreatitisPancreatic digestive enzyme blockade in the intestine increases survival after experimental shock.Cross-transfusion of postshock mesenteric lymph provokes acute lung injuryIntraluminal nonbacterial intestinal components control gut and lung injury after trauma hemorrhagic shock.2008 Landis Award lecture. Inflammation and the autodigestion hypothesis.Superior outcome of nafamostat mesilate as an anticoagulant in patients undergoing maintenance hemodialysis with intracerebral hemorrhage.Gender differences in small intestinal perfusion following trauma hemorrhage: the role of endothelin-1.Enteral tranexamic acid attenuates vasopressor resistance and changes in α1-adrenergic receptor expression in hemorrhagic shock.Vascular endothelial cell injury partly induced by mesenteric lymph in heat stroke.Pancreatic duct ligation reduces lung injury following trauma and hemorrhagic shock.
P2860
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P2860
Serine proteases are involved in the pathogenesis of trauma-hemorrhagic shock-induced gut and lung injury.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Serine proteases are involved ...... k-induced gut and lung injury.
@en
Serine proteases are involved ...... k-induced gut and lung injury.
@nl
type
label
Serine proteases are involved ...... k-induced gut and lung injury.
@en
Serine proteases are involved ...... k-induced gut and lung injury.
@nl
prefLabel
Serine proteases are involved ...... k-induced gut and lung injury.
@en
Serine proteases are involved ...... k-induced gut and lung injury.
@nl
P2093
P1433
P1476
Serine proteases are involved ...... k-induced gut and lung injury.
@en
P2093
Da Zhong Xu
Eleonora Feketeova
Han Ping Shi
P304
P356
10.1097/01.SHK.0000048899.46342.F6
P577
2003-05-01T00:00:00Z